ZnO-beta zeolite mediated simple and efficient
method for the one-pot synthesis of quinoxaline
derivatives at room temperature
Table 4. Reusability of ZnO-beta zeolite catalyst for the synthesis of
Table 5. Comparison of ZnO-beta zeolite with other catalyst for the
a
a
2
, 3-diphenylquinoxaline (Table 3, Entry 1).
synthesis of 2,3 diphenylquinoxaline (Table 3, Entry 3a) .
Entry
Cycle
1
2
3
Second
97
4
Entry Catalyst/Solvent
Time Yield
Refer-
ence
(min)
(%)
Fresh
98
First
98
Third
96
1
2
3
4
5
ZnO-beta/EtOH
8
98
Present
[35]
Yield (%)
Polyaniline sulphate salt/CH Cl2
20
95
2
a
All reactions carried out at RT in EtOH
Isolated yields.
CuSO .5H O/CH COOH
10
95
[31]
b
4
2
3
I2/DMSO
35
95
[29]
A comparison of the catalytic efficiency of ZnO-
beta zeolite with selected previously known catalysts
is collected in Table 5 to demonstrate that the present
protocol is indeed superior to several of the other
protocols. Most of the protocols listed take either longer
reaction times or use high temperatures.
Mont. K-10/water
150
100
[32]
a
All reaction was carried out at RT
Isolated yields.
b
Acknowledgements
The authors are thankful to the Head, Department of
Chemistry, Dr. Babasaheb Ambedkar Marathwada
University,Aurangabad-431004(MS), Indiaforproviding
4
. Conclusion
In summary, the present study confirms the applicability the laboratory facility.
of modified beta zeolite as an effective and reusable
catalyst for one-pot synthesis of quinoxalines. The
proposed method has several benefits, such as short
reaction time, mild reaction condition, easy work-up
procedure and minimum amount of catalyst loading.
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