138538-42-8 Usage
Uses
Used in Pharmaceutical Industry:
4-Pyrimidinecarboxylic acid, 6-methyl(9CI) is used as a key intermediate in the synthesis of pyrimidine-based drugs. Its unique structure allows for the development of new medications with potential applications in treating various diseases and conditions.
Used in Agrochemical Industry:
In the agrochemical sector, 4-Pyrimidinecarboxylic acid, 6-methyl(9CI) is utilized as a building block for the creation of novel agrochemicals. Its incorporation into these compounds can lead to the development of more effective and targeted pest control solutions.
Used in Medical Research:
4-Pyrimidinecarboxylic acid, 6-methyl(9CI) is employed in medical research for its potential anti-inflammatory and anti-tumor properties. Researchers are exploring its use in the development of new therapeutic agents that could offer innovative treatment options for patients suffering from inflammatory conditions and cancer.
Used in Drug Development:
As a compound with demonstrated biological activities, 4-Pyrimidinecarboxylic acid, 6-methyl(9CI) is a valuable asset in drug development. Its potential to contribute to the creation of new pharmaceuticals makes it an important component in the ongoing quest to discover and produce more effective treatments for a wide range of health issues.
Check Digit Verification of cas no
The CAS Registry Mumber 138538-42-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,8,5,3 and 8 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 138538-42:
(8*1)+(7*3)+(6*8)+(5*5)+(4*3)+(3*8)+(2*4)+(1*2)=148
148 % 10 = 8
So 138538-42-8 is a valid CAS Registry Number.
138538-42-8Relevant articles and documents
Reaction of β-alkoxyvinyl α-ketoesters with acyclic NCN binucleophiles – Scalable approach to novel functionalized pyrimidines
Stepaniuk, Oleksandr O.,Rudenko, Tymofii V.,Vashchenko, Bohdan V.,Matvienko, Vitalii O.,Kondratov, Ivan S.,Tolmachev, Andrey A.,Grygorenko, Oleksandr O.
supporting information, p. 3472 - 3478 (2019/05/17)
Two protocols for synthesis of series of low-molecular-weight di- and tri-substituted pyrimidines bearing a functional group at the 4th position, which rely on a base-mediated condensation of amidines or guanidines with β-alkoxyvinyl α-keto esters, have been developed. This approach allowed for multigram preparation of novel pyrimidine-4-carboxylates in 21–90% yield. The synthetic utility of these compounds was demonstrated by some standard functional group transformations providing promising building blocks for organic synthesis and drug discovery.
METALLOPROTEASE INHIBITORS
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Page/Page column 67, (2008/06/13)
The present invention relates to amide containing aromatic MMP inhibiting compounds with a mono-amide heteroaromatic group, of formulas I and II:
