141815-43-2 Usage
Uses
Used in Pharmaceutical Research:
C-(4-PYRIDIN-3-YLMETHYL-MORPHOLIN-2-YL)-METHYLAMINE TRIHYDROCHLORIDE is used as a research chemical for the development of new pharmaceutical agents. Its unique structure may provide specific binding affinities or interactions with biological targets, making it a candidate for drug discovery and medicinal chemistry studies.
Used in Chemical Synthesis:
In the chemical synthesis industry, C-(4-PYRIDIN-3-YLMETHYL-MORPHOLIN-2-YL)-METHYLAMINE TRIHYDROCHLORIDE is used as a building block or intermediate in the creation of more complex molecules. Its functional groups and structural features can be further modified to produce a variety of chemical products with different applications.
Safety and Handling:
It is crucial to handle C-(4-PYRIDIN-3-YLMETHYL-MORPHOLIN-2-YL)-METHYLAMINE TRIHYDROCHLORIDE with care due to its potential health hazards. It should be used in a controlled laboratory environment with appropriate safety measures, including personal protective equipment and proper disposal methods, to minimize risks to researchers and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 141815-43-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,1,8,1 and 5 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 141815-43:
(8*1)+(7*4)+(6*1)+(5*8)+(4*1)+(3*5)+(2*4)+(1*3)=112
112 % 10 = 2
So 141815-43-2 is a valid CAS Registry Number.
141815-43-2Relevant articles and documents
Novel benzamides as selective and potent gastrokinetic agents. III. Synthesis and structure-activity relationships of 4-amino-5-chloro-2-methoxy- and 2-ethoxy-N-[(4-substituted 2-morpholinyl)methyl]-benzamides
Kato,Morie,Harada,Yoshida,Matsumoto
, p. 652 - 660 (2007/10/02)
A series of 4-amino-5-chloro-2-methoxy- and 2-ethoxy-N-[(4-substituted 2-morpholinyl)methyl]benzamides (11-44) were prepared and evaluated for gastrokinetic activity by determining their effects on the gastric emptying of phenol red semisolid meal in rats. The N-4 substituent includes alkyl, phenoxyalkyl, (4-fluorobenzoyl)alkyl, and heteroarylmethyl groups. The benzamide derivatives, having an isopropyl, isoamyl, neopentyl, 3-(4-chlorophenoxy)propyl, or pyridylmethyl group at N-4, showed potent in vivo gastric emptying activity. In particular, 4-amino-5-chloro-2-ethoxy-N-[[4-(3-pyridylmethyl)-2-morpholinyl]methyl ]benzamide (57b) was equipotent to the 4-fluorobenzyl analogue 1b (AS-4370 as its citrate) in the gastrokinetic activity on phenol red semisolid meal in rats and mice, and on resin pellet solid meal in rats. Moreover, compound 57b was free from dopamine D2 receptor antagonistic activity in both in vitro ([3H]spiperone binding) and in vivo (apomorphine-induced emesis in dogs) tests. Structure-activity relationships of compounds with various substituents at N-4 are also discussed.
