141901-74-8Relevant articles and documents
Nonsteroidal antiinflammatory agents. Part 21: Optically active stereoisomers of p-trifluoromethylphenyl- and p-thioanisyl-biphenylyl-hydroxypropionic acids
Varoli,Burnelli,Guarnieri,Scapini,Andrisano,Lumachi
, p. 174 - 177 (2007/10/02)
The synthesis, diastereomeric separation, assignment to erythro- and threo-configuration by 1HNMR, and optical resolution of 3-(p-trifluoromethyl-phenyl)- and (p-thioanisyl)-2-biphenylyl-3-hydroxypropionic acids are described. The enantiomers were submitted to a preliminary assay to determine antiinflammatory activity.