142062-27-9

Basic information

• Product Name: 3-(methoxydimethylsilyl)-N,N-dimethylpropan-1-amine
• Synonyms: 3-(methoxydimethylsilyl)-N,N-dimethylpropan-1-amine
• CAS NO: 142062-27-9
• Molecular Formula: C₈H₂₁NOSi
• Molecular Weight: 175.34394
• Mol File: 142062-27-9.mol

Chemical Properties

• Boiling Point: 166.4±23.0 °C(Predicted)
• Appearance: /
• Density: 0.835±0.06 g/cm3(Predicted)
• PKA: 9.63±0.28(Predicted)
• CAS DataBase Reference: 3-(methoxydimethylsilyl)-N,N-dimethylpropan-1-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(methoxydimethylsilyl)-N,N-dimethylpropan-1-amine(142062-27-9)
• EPA Substance Registry System: 3-(methoxydimethylsilyl)-N,N-dimethylpropan-1-amine(142062-27-9)

Safety Data

• Hazardous Substances Data: 142062-27-9(Hazardous Substances Data)

Usage

Uses

Used in Materials Science:
3-(Methoxydimethylsilyl)-N,N-dimethylpropan-1-amine is used as a component in the development of new materials due to its organosilicon nature, which can influence the properties of materials in various ways.
Used in Polymers:
3-(methoxydimethylsilyl)-N,N-dimethylpropan-1-amine is used as a monomer or a modifier in the synthesis of polymers, where its unique structure can impart specific characteristics to the resulting polymers.
Used in Surfactants:
3-(Methoxydimethylsilyl)-N,N-dimethylpropan-1-amine is used as a surfactant or a component in surfactant formulations, potentially improving the performance of these compounds in various applications.
Used as a Protecting Group in Organic Synthesis:
The methoxydimethylsilyl functional group in this molecule may serve as a protecting group in organic synthesis, allowing for selective reactions and protecting certain functional groups during the synthesis process.

Upstream product

• 2530-86-1 <3-(dimethylamino)propyl>trimethoxysilane 
• 676-58-4 methylmagnesium chloride 
• 18171-14-7 γ-chloropropylmethoxydimethylsilane 
• 124-40-3 dimethyl amine 

Relevant articles and documents

Silicon α-effect: A systematic experimental and computational study of the hydrolysis of Cα- and Cγ-functionalized alkoxytriorganylsilanes of the formula type ROSiMe2(CH 2)nX (R = Me, Et; N = 1, 3; X = functional group)

To understand the silicon α-effect in terms of an enhanced reactivity of the Si-OC bond of α-silanes of the formula type ROSiMe 2CH2X compared to analogous γ-silanes ROSiMe 2(CH2)3X (R = Me, Et; X = functional group), a systematic experimental and computational study of the kinetics and mechanisms of hydrolysis of such compounds was performed. For this purpose, a series of suitable model compounds was synthesized and studied for their hydrolysis kinetics in CD3CN/D2O under basic and acidic conditions, using 1H NMR spectroscopy as the analytical tool. To get more information about the reaction mechanisms, the experimental investigations were complemented by computational studies. These investigations demonstrated that the silicon α-effect cannot be rationalized in terms of a special single effect. The reactivities observed rather result from a summation of different components, such as electronic and steric effects, pD dependence, and hydrogen bonds between the functional group (or even protonated functional group) and the alkoxy leaving group. Therefore, the term silicon α-effect should not be used furthermore to explain the hydrolysis reactivity at the silicon atom of alkoxyorganylsilanes with functional groups in α- or γ-position of the organyl groups (so-called α- or γ-silanes).

TOPICAL DELIVERY OF PHTHALOCYANINES

The invention relates to topical pharmaceutical compositions comprising a phthalocyanine, wherein a diamagnetic metal ion moiety is either coordinated or covalently bound to the phthalocyanine core. The invention also relates to methods for destroying cancer tissue, precancerous cells, photo-aged cells, damaged cells, or otherwise pathologic cells, or activated cells, such as lymphocytes or other cells of the immune system, or activated or inflamed tissue cells comprising topically administering to the cancer tissue or surrounding tissue an effective amount of a phthalocyanine composition.