1455037-43-0 Usage
Uses
Used in Pharmaceutical Industry:
Trans-3-fluoro-3-methylcyclobutane-1-carboxylic acid serves as a key intermediate in the synthesis of various pharmaceuticals. Its unique cyclobutane ring structure and functional groups contribute to the development of new drugs with specific therapeutic properties.
Used in Organic Chemistry Research:
As a building block in organic chemistry, trans-3-fluoro-3-methylcyclobutane-1-carboxylic acid is utilized for the synthesis of complex organic compounds. Its distinct structure allows for the exploration of novel chemical reactions and the creation of new molecules with potential applications in various fields.
Used in Drug Discovery Research:
In drug discovery, trans-3-fluoro-3-methylcyclobutane-1-carboxylic acid plays a crucial role as a starting material for the development of new therapeutic agents. Its unique structural features enable the design and synthesis of innovative compounds with improved pharmacological properties and selectivity.
Check Digit Verification of cas no
The CAS Registry Mumber 1455037-43-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,5,5,0,3 and 7 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1455037-43:
(9*1)+(8*4)+(7*5)+(6*5)+(5*0)+(4*3)+(3*7)+(2*4)+(1*3)=150
150 % 10 = 0
So 1455037-43-0 is a valid CAS Registry Number.
1455037-43-0Relevant articles and documents
Synthesis and Physicochemical Properties of 3-Fluorocyclobutylamines
Chernykh, Anton V.,Radchenko, Dmytro S.,Chernykh, Alla V.,Kondratov, Ivan S.,Tolmachova, Nataliya A.,Datsenko, Olexandr P.,Kurkunov, Maxim A.,Zozulya, Sergey X.,Kheylik, Yuri P.,Bartels, Katharina,Daniliuc, Constantin G.,Haufe, Günter
, p. 6466 - 6471 (2015/10/19)
Hitherto unknown cis- and trans-3-alkyl- and 3-aryl-3-fluorocycobutylamines have been synthesised selectively from 3-oxocyclobutane carboxylic acid in six or seven steps. Comparison of their pKa and logD values with those of the fluorine-free p
N-Acyl-N'-(pyridin-2-yl) Ureas and Analogs Exhibiting Anti-Cancer and Anti-Proliferative Activities
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Paragraph 0410, (2014/09/30)
Described are compounds of Formula I which find utility in the treatment of cancer, autoimmune diseases and metabolic bone disorders through inhibition of c-FMS (CSF-1R), c-KIT, and/or PDGFR kinases. These compounds also find utility in the treatment of other mammalian diseases mediated by c-FMS, c-KIT, or PDGFR kinases.
RAF INHIBITOR COMPOUNDS
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Page/Page column 79-80, (2013/09/26)
This invention provides compounds of Formula (I) or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising a compound of Formula (I); and use of a compound of Formula (I) for treating specified cancers.
