145631-84-1

Basic information

• Product Name: L-threo-Pentonic acid, 2,3-anhydro-4,5-dideoxy-4-methyl-, ethyl ester (9CI)
• Synonyms: L-threo-Pentonic acid, 2,3-anhydro-4,5-dideoxy-4-methyl-, ethyl ester (9CI)
• CAS NO: 145631-84-1
• Molecular Formula: C₈H₁₄O₃
• Molecular Weight: 158.19496
• Product Categories: ISOPROPYL
• Mol File: 145631-84-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: L-threo-Pentonic acid, 2,3-anhydro-4,5-dideoxy-4-methyl-, ethyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: L-threo-Pentonic acid, 2,3-anhydro-4,5-dideoxy-4-methyl-, ethyl ester (9CI)(145631-84-1)
• EPA Substance Registry System: L-threo-Pentonic acid, 2,3-anhydro-4,5-dideoxy-4-methyl-, ethyl ester (9CI)(145631-84-1)

Safety Data

• Hazardous Substances Data: 145631-84-1(Hazardous Substances Data)

Upstream product

• 124716-76-3 ethyl 4-methyl-2-<(p-nitrobenzenesulfonyl)oxy>-3-hydroxypentanoate 
• 124716-76-3 ethyl 4-methyl-2-<(p-nitrobenzenesulfonyl)oxy>-3-hydroxypentanoate 
• 105-39-5 chloroacetic acid ethyl ester 
• 78-84-2 isobutyraldehyde 
• 124716-80-9 Ethyl 2-<<(p-nitrophenyl)sulfonyl>oxy>-2-isobutyrylacetate 
• 136890-98-7 4-methyl-1,3-bis<(trimethylsilyl)oxy>-1-ethoxy-1-pentene 
• 15790-86-0 ethyl-4-methyl-2-(E)-penteneoate 

Downstream Products

• 139618-65-8 Ethyl trans-3-isopropylaziridine-2-carboxylate 
• 139618-85-2 (2S,3R)-1-(3,5-Dinitro-benzoyl)-3-isopropyl-aziridine-2-carboxylic acid ethyl ester 

Relevant articles and documents

A convenient synthesis of aziridine-2-carboxylic esters

Optically active oxirane-2-carboxylic esters, prepared from allylic alcohols employing the Sharpless epoxidation, were treated with sodium azide.The azido alcohols obtained were subsequently converted into aziridine-2-carboxylic esters by reaction with triphenylphosphine, in good yields and with high optical purity.Various racemic oxirane-2-carboxylic esters were subjected to the same sequence of reactions.

Synthesis and Reactions of 3-Hydroxy-2-nosyloxy Esters Produced by the Stereoselective Reduction of 2-Nosyloxy-3-keto Esters

The reduction of 2-nosyloxy-3-keto esters is an effective method for the preparation of 3-hydroxy-2-nosyloxy esters.The reduction is stereoselective for the syn isomer.The anti isomer can be produced as the major product by the addition of p-nitrobenzenesulfonyl peroxide to ketene bis-silyl acetal derivatives of 3-hydroxy esters.The diastereomers are separable chromatographically and can be converted stereospecifically to glycidic esters and 2-azido-3-hydroxy esters.As such they appear to have excellent potential as versatile synthetic intermediates for the synthesis of 1,2,3-trifunctional substances.

AN IMPROVED PROCEDURE FOR THE SYNTHESIS OF GLYCIDIC ESTERS

Aromatic and aliphatic aldehydes and ketones readily undergo Darzens condensation on reaction with NaH and chloroacetate in CH3CN.