Divergent Asymmetric Syntheses of Dioxolane Nucleoside Analogues
Oxidative degradation of benzyloxymethylacetals derived from D-mannitol or L-ascorbic acid provides dioxolane intermediate 6 and 7 useful in the synthesis of all the stereoisomers of dioxolane nucleoside analogues.
Evans, Colleen A.,Dixit, Dilip M.,Siddiqui, M. Arshad,Jin, Haolun,Tse, H. L. Allan,et al.
p. 2319 - 2322
(2007/10/02)
Oxidative Degradation of L-Ascorbic Acid Acetals to 2',3'-Dideoxy-3'-Oxaribofuranosides. Synthesis of Enantiomerically Pure 2',3'-Dideoxy-3'-Oxacytidine Stereoisomers as Potential Antiviral Agents
Enantiomerically pure 2',3'-dideoxy-3'-oxacytidine nucleoside analogues were synthesized from L-ascorbic acid in eight steps and good overall yield.
Belleau, Bernard R.,Evans, Colleen A.,Tse, H. L. Allan,Jin, Haolun,Dixit, Dilip M.,Mansour, Tarek S.
p. 6949 - 6952
(2007/10/02)
More Articles about upstream products of 145876-08-0