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1-Bromo-4-chloro-2-fluoro-5-methoxy-benzene is a chemical compound with the molecular formula C7H5BrClFOMe. It is a substituted benzene derivative featuring a bromine, chlorine, fluorine, and methoxy group attached to the benzene ring. This versatile compound is known for its wide range of potential applications in the field of chemistry and materials science.

146447-18-9

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146447-18-9 Usage

Uses

Used in Organic Synthesis:
1-Bromo-4-chloro-2-fluoro-5-methoxy-benzene is used as a starting material in the production of various pharmaceuticals and agrochemicals. Its unique structure allows for the synthesis of a variety of compounds with different biological activities and properties.
Used in the Development of New Materials and Polymers:
1-Bromo-4-chloro-2-fluoro-5-methoxy-benzene serves as a building block in the development of new materials and polymers. Its presence in these materials can impart specific characteristics, such as improved stability, enhanced properties, or novel functionalities.
Used in the Chemical Industry:
1-Bromo-4-chloro-2-fluoro-5-methoxy-benzene is utilized in the chemical industry for various applications, including the synthesis of intermediates, catalysts, and other specialty chemicals. Its unique combination of functional groups makes it a valuable component in the development of innovative products and processes.

Check Digit Verification of cas no

The CAS Registry Mumber 146447-18-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,6,4,4 and 7 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 146447-18:
(8*1)+(7*4)+(6*6)+(5*4)+(4*4)+(3*7)+(2*1)+(1*8)=139
139 % 10 = 9
So 146447-18-9 is a valid CAS Registry Number.
InChI:InChI=1/C7H5BrClFO/c1-11-7-2-4(8)6(10)3-5(7)9/h2-3H,1H3

146447-18-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-bromo-4-chloro-2-fluoro-5-methoxybenzene

1.2 Other means of identification

Product number -
Other names 5-bromo-2-chloro-4-fluoroanisole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:146447-18-9 SDS

146447-18-9Downstream Products

146447-18-9Relevant articles and documents

POLYCYCLIC PYRAZOLINONE DERIVATIVE AND HERBICIDE COMPRISING SAME AS EFFECTIVE COMPONENT THEREOF

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Paragraph 0586; 0589, (2016/02/19)

Provided are a polycyclic pyrazolinone derivative indicated by general formula (1) (in the formula, R1, X1, X2, X3, and Y indicate the definitions provided in the Specification) and a herbicide comprising same as effective component thereof.

PYRAZOLINE-3-ON DERIVATIVE AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT

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Paragraph 0165, (2016/10/08)

PROBLEM TO BE SOLVED: To provide a compound having excellent weed controlling effect and useful as an active ingredient of a herbicide. SOLUTION: There are provided a pyrazoline-3-on derivative represented by the following formula (1), where R1

PYRAZOLINONE DERIVATIVE, MANUFACTURING METHOD THEREFOR AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT

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Paragraph 0245, (2016/10/09)

PROBLEM TO BE SOLVED: To provide a compound having excellent weed controlling effect and useful as an active ingredient of a herbicide. SOLUTION: There are provided a pyrazolinone derivative represented by the formula (1), a manufacturing method therefor and herbicide containing the same. (1), where R1 is a halogen atom, R2 and R3 are integrally a trimethylene group (-(CH2)3-), a tetramethylene group (-(CH2)4-), a pentamethylene group (-(CH2)5-) or an oxydiethylene group (-(CH2)2O(CH2)2-), R4 is H or a halogen atom, R5 is a halogen atom, Ar is 3-oxo-1,4-benzoxazine-5-yl group, a 2,2-difluoro-3-oxo-1,4-benzoxazine-5-yl group or a 3,4-dihydro-2-oxo quinoxaline-5-yl group. SELECTED DRAWING: None COPYRIGHT: (C)2016,JPOandINPIT

Isoxazolo[3,4-b]quinoline-3,4(1H,9H)-diones as unique, potent and selective inhibitors for Pim-1 and Pim-2 kinases: Chemistry, biological activities, and molecular modeling

Tong, Yunsong,Stewart, Kent D.,Thomas, Sheela,Przytulinska, Magdalena,Johnson, Eric F.,Klinghofer, Vered,Leverson, Joel,McCall, Owen,Soni, Niru B.,Luo, Yan,Lin, Nan-horng,Sowin, Thomas J.,Giranda, Vincent L.,Penning, Thomas D.

scheme or table, p. 5206 - 5208 (2009/05/07)

A series of isoxazolo[3,4-b]quinoline-3,4(1H,9H)-diones were synthesized as potent inhibitors against Pim-1 and Pim-2 kinases. The structure-activity-relationship studies started from a high-throughput screening hit and was guided by molecular modeling of inhibitors in the active site of Pim-1 kinase. Installing a hydroxyl group on the benzene ring of the core has the potential to form a key hydrogen bond interaction to the hinge region of the binding pocket and thus resulted in the most potent inhibitor, 19, with Ki values at 2.5 and 43.5 nM against Pim-1 and Pim-2, respectively. Compound 19 also exhibited an activity profile with a high degree of kinase selectivity.

2-(POLY-SUBSTITUTED ARYL)-6-AMINO-5-HALO-4-PYRIMIDINECARBOXYLIC ACIDS AND THEIR USE AS HERBICIDES

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Page/Page column 26, (2008/06/13)

6-Amino-5-halo-4-pyrirnidinecarboxylic acids having poly-substituted aryl substituents in the 2-position, and their amine and acid derivatives, are potent herbicides demonstrating a broad spectrum of weed control.

6-(Poly-substituted aryl)-4-aminopicolinates and their use as herbicides

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Page/Page column 8, (2008/06/13)

4-Aminopicolinic acids having tri- and tetra-substituted aryl substituents in the 6-position, and their amine and acid derivatives, are potent herbicides demonstrating a broad spectrum of weed control.

Substituted piperazines

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, (2008/06/13)

Compounds are provided that act as potent antagonists of the CCR1 receptor, and which have been further confirmed in animal testing for inflammation, one of the hallmark disease states for CCR1. The compounds are generally aryl piperazine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists.

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