146796-45-4 Usage
Uses
Used in Organic Synthesis:
(3,5-dimethylisoxazol-4-yl)methanethiol is used as a reagent in organic synthesis for its unique reactivity and functional properties, contributing to the formation of various complex organic molecules.
Used in Pharmaceutical Research:
In pharmaceutical research, (3,5-dimethylisoxazol-4-yl)methanethiol is utilized as a building block for the development of new drugs, owing to its potential to modulate cellular signaling pathways and its biological activities.
Used in Fragrance and Flavor Production:
(3,5-dimethylisoxazol-4-yl)methanethiol is used as a key component in the production of certain fragrances and flavors due to its distinctive odor, adding unique scents and tastes to various products.
Used in Antibacterial Applications:
(3,5-dimethylisoxazol-4-yl)methanethiol has been studied for its potential antibacterial properties, making it a candidate for use in applications that require antimicrobial effects, such as in the development of new antibiotics or disinfectants.
Check Digit Verification of cas no
The CAS Registry Mumber 146796-45-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,6,7,9 and 6 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 146796-45:
(8*1)+(7*4)+(6*6)+(5*7)+(4*9)+(3*6)+(2*4)+(1*5)=174
174 % 10 = 4
So 146796-45-4 is a valid CAS Registry Number.
146796-45-4Relevant articles and documents
Small Molecule Antagonists of the Nuclear Androgen Receptor for the Treatment of Castration-Resistant Prostate Cancer
Johnson, James K.,Skoda, Erin M.,Zhou, Jianhua,Parrinello, Erica,Wang, Dan,O'Malley, Katherine,Eyer, Benjamin R.,Kazancioglu, Mustafa,Eisermann, Kurtis,Johnston, Paul A.,Nelson, Joel B.,Wang, Zhou,Wipf, Peter
, p. 785 - 790 (2016/08/24)
After a high-throughput screening campaign identified thioether 1 as an antagonist of the nuclear androgen receptor, a zone model was developed for structure-activity relationship (SAR) purposes and analogues were synthesized and evaluated in a cell-based luciferase assay. A novel thioether isostere, cyclopropane (1S,2R)-27, showed the desired increased potency and structural properties (stereospecific SAR response, absence of a readily oxidized sulfur atom, low molecular weight, reduced number of flexible bonds and polar surface area, and drug-likeness score) in the prostate-specific antigen luciferase assay in C4-2-PSA-rl cells to qualify as a new lead structure for prostate cancer drug development.
