19788-37-5

Basic information

• Product Name: 4-(CHLOROMETHYL)-3,5-DIMETHYLISOXAZOLE
• Synonyms: 4-(CHLOROMETHYL)-3,5-DIMETHYLISOXAZOLE;AKOS BC-3064;TIMTEC-BB SBB004107;4-(chloromethyl)-3,5-dimethyl-isoxazol;3,5-Dimethyl-4-chloromethyl isoxazole;4-(Chloromethyl)-3,5-dimethylisoxazole,98%;4-(Chloromethyl)-3,5-dimethylisoxazole,96%;4-(chloromethyl)-3,5-dimethylisoxazole(SALTDATA: FREE)
• CAS NO: 19788-37-5
• Molecular Formula: C₆H₈ClNO
• Molecular Weight: 145.59
• EINECS: 243-312-4
• Product Categories: Oxazole&Isoxazole;Halogenated Heterocycles;Heterocyclic Building Blocks;Isoxazoles;IsoxazolesBuilding Blocks
• Mol File: 19788-37-5.mol
• Article Data: 6

Chemical Properties

• Melting Point: 88-90°C
• Boiling Point: 87-88 °C8 mm Hg(lit.)
• Flash Point: 204 °F
• Appearance: Colorless to yellow liquid
• Density: 1.173 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.167mmHg at 25°C
• Refractive Index: n20/D 1.486(lit.)
• Storage Temp.: 0-6°C
• PKA: -1.73±0.28(Predicted)
• BRN: 110780
• CAS DataBase Reference: 4-(CHLOROMETHYL)-3,5-DIMETHYLISOXAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(CHLOROMETHYL)-3,5-DIMETHYLISOXAZOLE(19788-37-5)
• EPA Substance Registry System: 4-(CHLOROMETHYL)-3,5-DIMETHYLISOXAZOLE(19788-37-5)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 20/21/22-36/37/38-37/38-36
• Safety Statements: 26-36
• RIDADR: UN 3334
• WGK Germany: 3
• TSCA: Yes
• HazardClass: IRRITANT
• Hazardous Substances Data: 19788-37-5(Hazardous Substances Data)

Usage

Chemical Properties

Colorless to yellow liquid

Uses

4-Chloromethyl-3,5-dimethylisoxazole has been used in the preparation of:4(3-oxoalkyl)isoxazole(E)-3,5-dimethyl-4-(2-(thiophene-3-yl)vinyl)isoxazole

General Description

4-Chloromethyl-3,5-dimethylisoxazole participates in asymmetric isoxazole annulation reaction.

InChI:InChI=1/C6H8ClNO/c1-4-6(3-7)5(2)9-8-4/h3H2,1-2H3

Upstream product

• 300-87-8 3,5-dimethyl-1,2-oxazole 
• 50-00-0 formaldehyd 
• 19788-36-4 4-hydroxymethyl-3,5-dimethylisoxazole 

Downstream Products

• 103041-81-2 N-(3,5-dimethyl-isoxazol-4-ylmethyl)-N',N'-dimethyl-N-phenyl-ethylenediamine 
• 19788-36-4 4-hydroxymethyl-3,5-dimethylisoxazole 
• 2510-36-3 3,5-dimethyl-4-isoxazolecarboxylic acid 
• 36873-71-9 2-(3,5-dimethyl-isoxazol-4-ylmethyl)-3-methyl-cyclohexanone 
• 39962-28-2 N-<(3,5-Dimethyl-4-isoxazolyl)-methyl>-phthalimid 
• 16858-04-1 3,5-Dimethyl-4-(2-oxocyclopentyl)isoxazol 
• 19788-40-0 4-<2-Oxo-cyclohexylmethyl>-3,5-dimethyl-isoxazol 
• 28241-32-9 (3,5-dimethyl-isoxazol-4-ylmethyl)-triphenyl-phosphonium; chloride 
• 16858-07-4 3-(3,5-Dimethyl-4-isoxazolylmethyl)pentan-2,4-dion 
• 93548-18-6 ((3,5-dimethylisoxazole-4-yl)methoxy)ethane 
• 119750-79-7 (R)-3-(3,5-Dimethyl-isoxazol-4-yl)-2-methyl-2-phenyl-propionaldehyde 
• 119750-79-7 (S)-3-(3,5-Dimethyl-isoxazol-4-yl)-2-methyl-2-phenyl-propionaldehyde 
• 85679-14-7 1-(3,5-Dimethyl-isoxazol-4-ylmethyl)-cyclohex-3-enecarbaldehyde 
• 10557-82-1 3,4,5-trimethylisoxazole 

Relevant articles and documents

NOVEL PYRIMIDINE DERIVATIVES AND THEIR USE AS PPAR-ALPHA MODULATORS

The invention relates to novel pyrimidine derivatives of general formula (I), methods for the production thereof, their use for treating and/or preventing diseases, and to their use for producing medicaments for treating and/or preventing diseases, preferably for treating and/or preventing cardiovascular diseases, particularly dyslipidemia, arteriosclerosis, insufficiency of the heart, thrombosis and metabolic syndrome.

New triazole antifungal agents derived from mercaptomethylisoxazoles

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