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1-(2,4-difluorophenyl)-6-fluoro-5-methyl-7-[(3S)-3-methylpiperazin-1-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid is a complex chemical compound that belongs to the fluoroquinolone class of antibiotics. It is a derivative of the quinolone family and features a piperazine ring, which enhances its antimicrobial properties. 1-(2,4-difluorophenyl)-6-fluoro-5-methyl-7-[(3S)-3-methylpiperazin-1-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid has the ability to selectively inhibit bacterial DNA gyrase and topoisomerase IV, which are essential for bacterial DNA replication, ultimately leading to bacterial cell death.

146981-12-6

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146981-12-6 Usage

Uses

Used in Pharmaceutical Industry:
1-(2,4-difluorophenyl)-6-fluoro-5-methyl-7-[(3S)-3-methylpiperazin-1-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid is used as an antibiotic for the treatment of various bacterial infections. Its unique chemical structure and ability to inhibit essential bacterial enzymes make it a promising candidate for pharmaceutical research and development, potentially leading to the creation of new and effective treatments for a wide range of bacterial infections.
Used in Research and Development:
In the field of research and development, 1-(2,4-difluorophenyl)-6-fluoro-5-methyl-7-[(3S)-3-methylpiperazin-1-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid serves as an important compound for studying the mechanisms of action and resistance development in bacterial infections. Its complex molecular structure and potent antimicrobial activity provide valuable insights into the design and development of new antibiotics to combat drug-resistant bacteria.

Check Digit Verification of cas no

The CAS Registry Mumber 146981-12-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,6,9,8 and 1 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 146981-12:
(8*1)+(7*4)+(6*6)+(5*9)+(4*8)+(3*1)+(2*1)+(1*2)=156
156 % 10 = 6
So 146981-12-6 is a valid CAS Registry Number.

146981-12-6Downstream Products

146981-12-6Relevant academic research and scientific papers

Synthesis and Biological Activity of 5-Alkyl-1,7,8-trisubstituted-6-fluoroquinoline-3-carboxylic Acids

Hagen, Susan E.,Domagala, Johan M.,Heifetz, Carl L.,Johnson, Judith

, p. 1155 - 1161 (2007/10/02)

A series of 5-alkyl-1,7,8-trisubstituted-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids was prepared and evaluated for in vitro and in vivo antibacterial activity.When compared to the 5-hydrogen analogues, the presence of the 5-methyl group enhanc

Antibacterial agents

-

, (2008/06/13)

Novel naphthyridine-, and quinolinecarboxylic acids as antibacterial agents are described as well as methods for their manufacture, formulation, and use in treating bacterial infections including the description of certain novel intermediates used in the

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