147265-76-7

Basic information

• Product Name: Ethanone, 1-(2,3-dihydro-1H-indol-6-yl)- (9CI)
• Synonyms: Ethanone, 1-(2,3-dihydro-1H-indol-6-yl)- (9CI);Ethanone, 1-(2,3-dihydro-1H-indol-6-yl)-;1-(Indolin-6-yl)ethanone;1-(2,3-Dihydro-1H-indol-6-yl)ethanone
• CAS NO: 147265-76-7
• Molecular Formula: C₁₀H₁₁NO
• Molecular Weight: 161.20044
• Product Categories: ACETYLGROUP
• Mol File: 147265-76-7.mol

Chemical Properties

• Boiling Point: 322.3±31.0 °C(Predicted)
• Appearance: /
• Density: 1.103±0.06 g/cm3(Predicted)
• PKA: 4.22±0.20(Predicted)
• CAS DataBase Reference: Ethanone, 1-(2,3-dihydro-1H-indol-6-yl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(2,3-dihydro-1H-indol-6-yl)- (9CI)(147265-76-7)
• EPA Substance Registry System: Ethanone, 1-(2,3-dihydro-1H-indol-6-yl)- (9CI)(147265-76-7)

Safety Data

• Hazardous Substances Data: 147265-76-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research:
Ethanone, 1-(2,3-dihydro-1H-indol-6-yl)(9CI) is utilized as a research compound for exploring its potential biological activities and medicinal properties. Its indole ring system, a common structural motif in many bioactive molecules, suggests that it may interact with biological targets and pathways relevant to drug discovery.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, Ethanone, 1-(2,3-dihydro-1H-indol-6-yl)(9CI) serves as a starting material or a building block for the synthesis of more complex molecules with therapeutic potential. Its structural features may be optimized to enhance its pharmacological properties, such as potency, selectivity, and bioavailability.
Note: Since the provided materials do not specify particular applications or industries for Ethanone, 1-(2,3-dihydro-1H-indol-6-yl)(9CI), the uses listed above are general and based on the compound's potential in pharmaceutical research and medicinal chemistry. Further research would be necessary to identify specific applications and industries where this compound could be utilized.

Upstream product

• 16078-30-1 1-Acetyl-2,3-dihydro-1H-indole 
• 75-36-5 acetyl chloride 
• 90732-28-8 2,2,2-trifluoro-1-(indolin-1-yl)ethan-1-one 

Relevant articles and documents

Regioselective Friedel-Crafts Acylation of 1,2,3,4-Tetrahydroquinoline and Related Nitrogen Heterocycles: Effects of NH Protective Groups and Ring Size

Regioselectivity of the Friedel-Crafts acylation of the following nitrogen heterocyles was studied: 2,3-dihydro-1H-indoles 3, 1,2,3,4-tetrahydroquinolines 4, 2,3,4,5-tetrahydro-1H-1-benzazepines 5 and 1,2,3,4,5,6-hexahydro-1-benzazocines 6.It was found that though the ratio of regioisomers depends on ring size, it can be controlled by changing the NH protective groups.A molecular orbital (MO) calculation of the Lewis acid co-ordinated substrates gave a rational explanation of the regioselectivity.