147641-96-1

Basic information

• Product Name: (R)-1-(3,4-DICHLORO-PHENYL)-3-DIMETHYLAMINO-PROPAN-1-OL
• Synonyms: Benzenemethanol, 3,4-dichloro-.alpha.-[2-(dimethylamino)ethyl]-, (.alpha.R)-
• CAS NO: 147641-96-1
• Molecular Formula: C11H15Cl2NO
• Molecular Weight: 248.15
• Mol File: 147641-96-1.mol

Chemical Properties

• Boiling Point: 348.6°Cat760mmHg
• Flash Point: 164.6°C
• Appearance: /
• Density: 1.233g/cm³
• Vapor Pressure: 1.87E-05mmHg at 25°C
• Refractive Index: 1.556
• PKA: 13.55±0.20(Predicted)
• CAS DataBase Reference: (R)-1-(3,4-DICHLORO-PHENYL)-3-DIMETHYLAMINO-PROPAN-1-OL(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-(3,4-DICHLORO-PHENYL)-3-DIMETHYLAMINO-PROPAN-1-OL(147641-96-1)
• EPA Substance Registry System: (R)-1-(3,4-DICHLORO-PHENYL)-3-DIMETHYLAMINO-PROPAN-1-OL(147641-96-1)

Safety Data

• Hazardous Substances Data: 147641-96-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research:
(R)-1-(3,4-DICHLORO-PHENYL)-3-DIMETHYLAMINO-PROPAN-1-OL is used as a research compound for studying its psychoactive effects and potential applications in the development of new medications. Its unique properties as a stimulant and euphoric agent make it valuable for understanding the mechanisms of action and potential therapeutic uses in treating certain conditions.
Used in Forensic Toxicology:
In the field of forensic toxicology, (R)-1-(3,4-DICHLORO-PHENYL)-3-DIMETHYLAMINO-PROPAN-1-OL is utilized for the identification and analysis of controlled substances in biological samples. Its presence in samples can provide crucial information for investigations related to drug abuse, addiction, and related criminal activities.
Used in Drug Regulation and Policy Development:
(R)-1-(3,4-DICHLORO-PHENYL)-3-DIMETHYLAMINO-PROPAN-1-OL is used as a reference substance in the development and implementation of drug regulation policies. Its classification as a controlled substance helps inform the legal framework and guidelines for the prevention of recreational use and abuse, ensuring public health and safety.

InChI:InChI=1/C11H15Cl2NO/c1-14(2)6-5-11(15)8-3-4-9(12)10(13)7-8/h3-4,7,11,15H,5-6H2,1-2H3/t11-/m1/s1

Upstream product

• 2642-63-9 3',4'-dichloroacetophenone 
• 50516-63-7 1-(3,4-dichlorophenyl)-3-(dimethylamino)-1-propanone 

Downstream Products

• 1198348-58-1 [3-(3,4-dichloro-phenyl)-3-tetrazol-2-yl-propyl]-methyl-amine 
• 1198348-59-2 (S)-[3-(3,4-dichloro-phenyl)-3-tetrazol-2-yl-propyl]-methyl-amine 
• 1346460-38-5 3-(3,4-dichlorophenyl)-N,N-dimethyl-3-(pyrrolidin-1-yl)propan-1-amine hydrochloride 
• 1346460-39-6 3-(3,4-dichlorophenyl)-N,N-dimethyl-3-(piperazin-1-yl)propan-1-amine hydrochloride 
• 1346460-43-2 3-(3,4-dichlorophenyl)-N,N-dimethyl-3-(piperidin-1-yl)propan-1-amine hydrochloride 
• 1346460-40-9 3-(3,4-dichlorophenyl)-N,N-dimethyl-3-morpholinopropan-1-amine hydrochloride 

Relevant articles and documents

3-[(BENZO[D][1,3]DIOXOLAN-4-YL)-OXY]-3-ARYLPROPYLAMINE TYPE COMPOUNDS AND APPLICATIONS THEREOF

The present invention relates to 3-[(benzo[d][1,3]dioxolan-4-yl)-oxy]-3-arylpropylamine compounds of formula I or pharmaceutically acceptable salts thereof and use thereof. The compound may be used to prepare an antidepressant agent.

ARALKYL DIAMINE DERIVATIVES AND USES THEREOF AS ANTIDEPRESSANT

Aralkyl diamine derivative of the following formula, pharmaceutically acceptable salts or uses thereof as antidepressants. The derivatives have triplex inhibiting activities of the reuptake of 5-HT, dopamine and noradrenalin, which can be administered to the patients in need of such treatment in the form of compositions orally or injectedly et al.

Synthesis and pharmacological evaluation of 3-aryl-3-azolylpropan-1-amines as selective triple serotonin/norepinephrine/dopamine reuptake inhibitors

A series of 3-aryl-3-azolylpropan-1-amines was prepared and screened for its capability of inhibiting monoamine reuptake. Analogs with nanomolar potency, good human in vitro microsomal stability, and low drug-drug interaction potential were described. In

3-Substituted Propanamine Compounds

Racemic or enantiomerically enriched 3-substituted propanamine compounds represented by the following structural formula (I): or a pharmaceutically acceptable salt thereof are disclosed. Pharmaceutical compositions containing the subject compounds are als

3-SUBSTITUTED PROPANAMINE COMPOUNDS

Racemic or enantiomerically enriched 3-substituted propanamine compounds represented by the following structural formula (I) or a pharmaceutically acceptable salt thereof are disclosed. Pharmaceutical compositions containing the subject compounds are also

Enantioselective Oxazaborolidine Reduction of Ketones Containing Heteroatoms

Ketones which contain heteroatoms, particularly nitrogen, can be enantioselectively and catalytically reduced with chiral oxazaborolidines in the presence of excess borane. Key Words: Enantioselective reduction; Oxazaborolidine; Chiral alcohol; Catalytic reduction; Amine-borane

Diphenyloxazaborolidine a new catalyst for enantioselective reduction of ketones

A variety of ketones can be reduced in high enantioselectivity with the oxazaborolidines derived from commercially available erythro aminodiphenylethanol.