14774-77-7

Basic information

• Product Name: Lithium, (4-methoxyphenyl)-
• CAS NO: 14774-77-7
• Molecular Formula: C7H7LiO
• Molecular Weight: 114.073
• Mol File: 14774-77-7.mol

Chemical Properties

• CAS DataBase Reference: Lithium, (4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Lithium, (4-methoxyphenyl)-(14774-77-7)
• EPA Substance Registry System: Lithium, (4-methoxyphenyl)-(14774-77-7)

Safety Data

• Hazardous Substances Data: 14774-77-7(Hazardous Substances Data)

Upstream product

• 104-92-7 1-bromo-4-methoxy-benzene 
• 109-72-8 n-butyllithium 
• 459-60-9 1-fluoro-4-methoxybenzene 
• 696-62-8 para-iodoanisole 
• 594-19-4 tert.-butyl lithium 
• 591-51-5 phenyllithium 

Downstream Products

• 5957-90-4 4-(2-pyridinyl)anisole 
• 36710-91-5 1-(4-methoxy-phenyl)-isoquinoline; picrate 
• 101356-78-9 4-(4-methoxy-phenyl)-1,2,5-trimethyl-piperidin-4-ol 
• 199168-50-8 2-(4-methoxy-phenyl)-7-methyl-quinoline 
• 199168-51-9 (2-(4-methoxyphenyl)-6-methylquinoline) 
• 107027-60-1 (2-(4-methoxyphenyl)-8-methylquinoline) 
• 69035-42-3 9-(4-methoxy-phenyl)-9,10-dihydro-acridine 
• 877-68-9 4-trimethylsilylanisole 
• 101726-93-6 4,7-dichloro-2-(4-methoxy-phenyl)-quinoline 
• 80448-01-7 p-methoxyphenyl phenyl selenide 
• 6345-76-2 3-Hydroxy-3-(4-methoxyphenyl)-2-(pyridyl-2)-indanon-1 
• 14311-75-2 (4-methoxyphenyl)triethylsilane 
• 5331-23-7 3,4-bis-(4-methoxy-phenyl)-hexan-3-ol 
• 14311-02-5 (4-methoxy-phenyl)-tri-o-tolyl-silane 

Relevant articles and documents

Synthesis of Ether-Functionalized and Sterically Demanding Molybdenum Alkylidyne Complexes

The synthesis of ether-functionalized molybdenum benzylidyne complexes [ArC-Mo{OC(CF3)2Me}3] (6, Ar = para-methoxyphenyl; 7, Ar = 2,4,6-trimethoxyphenyl) and of the sterically demanding benzylidyne complex [{2,4,6-(i-Pr)3C6H2}C-Mo{OC(CF3)2Me}3] are presented, together with their spectroscopic characterization, molecular structures, and catalytic activity in alkyne metathesis. Complexes 6 and 7 feature intermolecular contacts between the para-methoxy group and the molybdenum center that give rise to 1D-polymeric structures in the solid state. The preparation of other functionalized alkylidyne complexes, [ArC-Mo{OC(CF3)2Me}3] (Ar = 2-(i-PrO)C6H4, 8-MeO-Naph, 2,6-(i-Pr)2C6H3), was also attempted, but only the acyl precursors [ArC(=O)Mo(CO)5]- could be isolated. The synthesis of the molybdenum acyl complexes was challenging, and appropriate alternative protocols were developed.

Five shades of green: Substituent influence on the (spectro-) electrochemical properties of diferrocenyl(phenyl)methylium dyes

Five new, intensely green diferrocenylphenylmethylium complexes 1+-5+ with electron donating (EDG: 4-MeO, 4-Me, 4-Br) or withdrawing (EWG: 3,5-CF3, 4-nC6F13) substituents were synthesized and fully characterized. The substituent influence on their electro

Generation of Phosphonium Sites on Sulfated Zirconium Oxide: Relationship to Br?nsted Acid Strength of Surface -OH Sites

The reaction of (tBu)2ArP (1a-h), where the para position of the Ar group contains electron-donating or electron-withdrawing groups, with sulfated zirconium oxide partially dehydroxylated at 300 °C (SZO300) forms [(tBu)2ArPH][SZO300] (2a-h). The equilibrium binding constants of 1a-h to SZO300 are related to the pKa of [(tBu)2ArPH]; R3P that form less acidic phosphoniums (high pKa values) bind stronger to SZO300 than R3P that form more acidic phosphoniums (low pKa values). These studies show that Br?nsted acid sites on the surface of SZO300 are not superacidic.

Synthesis of Benzosiloles by Intramolecular anti-Hydroarylation via ortho-C-H Activation of Aryloxyethynyl Silanes

Straightforward synthesis of benzosiloles was achieved by the invention of Pd/acid-catalyzed intramolecular anti-hydroarylation of aryloxyethynyl(aryl)silanes via ortho-C-H bond activation. The aryloxy group bound to the ethynyl carbon is the key factor for this transformation.

Nickel-Catalyzed Cross-Coupling of Organolithium Reagents with (Hetero)Aryl Electrophiles

Nickel-catalyzed selective cross-coupling of aromatic electrophiles (bromides, chlorides, fluorides and methyl ethers) with organolithium reagents is presented. The use of a commercially available nickel N-heterocyclic carbene (NHC) complex allows the reaction with a variety of (hetero)aryllithium compounds, including those prepared via metal-halogen exchange or direct metallation, whereas a commercially available electron-rich nickel-bisphosphine complex smoothly converts alkyllithium species into the corresponding coupled product. These reactions proceed rapidly (1 h) under mild conditions (room temperature) while avoiding the undesired formation of reduced or homocoupled products. Nickel-catalyzed cross-coupling of aromatic electrophiles with organolithium reagents is presented. The use of a commercially available nickel N-heterocyclic carbene complex allows reaction with a variety of (hetero)aryllithium compounds, whereas a commercially available electron-rich nickel bisphosphine complex smoothly converts alkyllithium species into the corresponding coupled product.

Copper-catalysed cross-coupling of arylzirconium reagents with aryl and heteroaryl iodides

An unprecedented CuI-catalysed cross-coupling of arylzirconium reagents with aryl and heteroaryl iodides is reported. Mechanistic studies with a Cp2ZrAr2 complex revealed that Cp2Zr(Ar)(Cl) is the reactive species that undergoes transmetalation with (PN-1)CuI. In addition, experiments with radical probes indicated that the reaction proceeds via a non-radical pathway. This journal is

Recyclable polystyrene-supported siloxane-transfer agent for palladium-catalyzed cross-coupling reactions

The rational design, synthesis, and validation of a significantly improved insoluble polymer-supported siloxane-transfer agent has been achieved that permits efficient palladium-catalyzed cross-coupling reactions. The cross-linked polystyrene support facilitates product purification with excellent siloxane recycling. Drawbacks of a previous polymer-supported siloxane-transfer agent, relating to reaction efficiency and polymer stability after repeated cycles, have been addressed.

An efficient titanium amidinate catalyzed version of Ziegler's "aufbaureaktion"

Diethylamidotitanium trichloride reacts with a variety of bulky amidines ArN(H)C(Ar′)NAr [Ar = 2,6-diisopropylphenyl; Ar′ = Ph, p-Me 2NC6H4, p-MeOC6H4, p-(2,5-dimethylpyrrole)C6H4/sub

FUSED PYRROLE DERIVATES AS ESTROGEN RECEPTOR LIGANDS

The invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein Z, A, B, D,E, G, M1, M2, M3, M4, M5, M6, p, q, r, R3, R4, R5 and R6 are as defined in the specification. The invention also provides the use of such co

Synthesis of tetramethylammonium phenyltrialkylborate salts by the addition of alkyllithium reagents to a triorganylborane or organoboranylhalides

Several new tetraorganylborate salts have been synthesized by the addition of alkyl or phenyllithium reagents to a triorganylborane or organoboranylhalides. The chemical structure of the borates was confirmed by 1H, 13C NMR and IR spectroscopic measurements and elemental analysis. Solubility, spectroscopic and electrochemical properties of these salts have been investigated as well. The structures of the phenyltrialkylborates were varied systematically to control their oxidation potential. These compounds are the trimethyl-, triethyl-, n-tributyl- and sec-tributylborate derivatives and form a series of substituted phenyltrialkylborates containing either electron-withdrawing or electron-donating substituents in the para position of phenyl ring. The oxidation potential of these borates has been found to be a function of Hammett constant.