147976-18-9

Basic information

• Product Name: (4S,5S)-4-benzyl-2-oxo-1,3-oxazolidine-5-carboxylic acid
• Synonyms: (4S,5S)-4-Benzyl-2-oxo-1,3-oxazolidine-5-carboxylic acid
• CAS NO: 147976-18-9
• Molecular Formula: C₁₁H₁₁NO₄
• Molecular Weight: 221.2093
• Mol File: 147976-18-9.mol

Chemical Properties

• Boiling Point: 536.7°C at 760 mmHg
• Flash Point: 278.4°C
• Density: 1.358g/cm³
• Vapor Pressure: 2.37E-12mmHg at 25°C
• Refractive Index: 1.579
• CAS DataBase Reference: (4S,5S)-4-benzyl-2-oxo-1,3-oxazolidine-5-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (4S,5S)-4-benzyl-2-oxo-1,3-oxazolidine-5-carboxylic acid(147976-18-9)
• EPA Substance Registry System: (4S,5S)-4-benzyl-2-oxo-1,3-oxazolidine-5-carboxylic acid(147976-18-9)

Safety Data

• Hazardous Substances Data: 147976-18-9(Hazardous Substances Data)

Upstream product

• 147976-16-7 (4S,5S)-5-hydroxymethyl-4-phenylmethyloxazolidinone 
• 79-22-1 methyl chloroformate 
• 161525-75-3 (2S,3S)-2-hydroxy-3-phthalimido-4-phenylbutyronitrile 
• 147915-02-4 (2S,3S)-3-amino-4-phenylbutane-1,2-diol 
• 147915-01-3 (2S,3S)-3-azido-1,2-O-methylethylidene-4-phenylbutane-1,2-diol 
• 140867-27-2 (2R,3R)-1,2-O-methylethylidene-4-phenylbutane-1,2,3-triol 
• 116949-67-8 (2S,3S)-2-azido-1-phenyl-butane-3,4-diol 
• 591-51-5 phenyllithium 
• 63-91-2 L-phenylalanine 
• 499783-30-1 ((S)-1-Benzyl-2-hydroxy-3-nitro-3-p-tolylsulfanyl-propyl)-carbamic acid tert-butyl ester 
• 499783-31-2 (Z)-(3S)-4-phenyl-3-(tert-butoxycarbanylamino)-1-(4'-tolylthio)-1-nitrobut-1-ene 
• 72155-45-4 Boc-L-phenylalaninal 
• 32150-91-7 phthaloyl-L-phenylalanyl chloride 
• 5123-55-7 Nα-phthaloyl-L-phenylalanine 

Downstream Products

• 162221-36-5 (4S,5S)-4-benzyl-2-oxo-oxazolidine-5-carboxylic acid methyl ether 
• 147976-16-7 (4S,5S)-5-hydroxymethyl-4-phenylmethyloxazolidinone 
• 162221-28-5 4-Nitro-benzenesulfonic acid (4S,5S)-4-benzyl-2-oxo-oxazolidin-5-ylmethyl ester 
• 136522-18-4 2-<3(S)-<amino>-2(R)-hydroxy-4-phenylbutyl>-N-tert-butyldecahydro-(4aS,8aS)-isoquinoline-3(S)-carboxamide 
• 137431-06-2 2-[3(S)-[(L-asparaginyl)-amino]-2(R)-hydroxy-4-phenylbutyl]-N-tert-butyl-decahydro(4aS,8aS)-isoquinoline-3(S)-carboxamide 
• 136522-17-3 cis-N-butyldecahydro-2-<2(R)-hydroxy-4-phenyl-3(S)-aminobutyl>-(4aS,8aS)-isoquinoline-3(S)-carboxamide 
• 127779-20-8 Saquinavir 

Relevant articles and documents

Facile synthetic route to (2S,3S)-3-amino-2-hydroxy-4-phenylbutyric acid and its derivatives, the key intermediates for HIV protease inhibitors

A facile and efficient route to (2S,3S)-3-amino-2-hydroxy-4-phenylbutyric acid and its derivative (4S,5S)-4-benzyl-5-hydroxymethyl oxazolidin-2-one is presented. N-phthaloyl protected L-phenylalanine 1 was treated with thionyl chloride followed by hydroge

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Process for the production of a β-amino alcohol

A process for producing 2-?3(S)-amino-2-(R)-hydroxyl-4-phenyl butyl!-N-tert,butyl decahydro-(4aS,8aS)-isoquinoline-e(S)-carboxamide of the formula (I) via 3(S)-?lower alkoxy carbonyl amino, phenoxy carbonyl amino or benzyl oxycarbonyl amino!-2-hydroxy-4-phenyl butyric acid and process for producing said acid.

Synthesis of the HIV-proteinase inhibitor Saquinavir: A challenge for process research

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Enantiomerically pure 3-amino-2-hydroxy and 5-amino-4-hydroxy acids from D-isoascorbic acid

The chirospecific synthesis of 3-amino-2-hydroxy aldehyde or acid units is an important issue in the context of synthetic strategies directed towards the construction of biologically relevant target molecules such as amino sugars, antibiotics, enzyme inhi