1487-09-8

Basic information

• Product Name: 3-broMo-2,5-diphenylfuran
• Synonyms: 3-broMo-2,5-diphenylfuran
• CAS NO: 1487-09-8
• Molecular Formula: C₁₆H₁₁BrO
• Molecular Weight: 299.16194
• Mol File: 1487-09-8.mol
• Article Data: 2

Chemical Properties

• Melting Point: 77 °C(Solv: methanol (67-56-1))
• Boiling Point: 358.8±37.0 °C(Predicted)
• Appearance: /
• Density: 1.366±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 3-broMo-2,5-diphenylfuran(CAS DataBase Reference)
• NIST Chemistry Reference: 3-broMo-2,5-diphenylfuran(1487-09-8)
• EPA Substance Registry System: 3-broMo-2,5-diphenylfuran(1487-09-8)

Safety Data

• Hazardous Substances Data: 1487-09-8(Hazardous Substances Data)

Usage

Uses

Used in Medicinal Chemistry:
3-Bromo-2,5-diphenylfuran is used as a building block in the synthesis of new pharmaceuticals due to its unique structure and reactivity. Its derivatives have been explored as potential drug candidates, making it a valuable component in the development of novel therapeutic agents.
Used in Materials Science:
In the field of materials science, 3-Bromo-2,5-diphenylfuran is utilized as a key component in the creation of new materials with specific properties. Its unique structure and reactivity contribute to the development of advanced materials with potential applications in various industries.
Used in Organic Synthesis:
3-Bromo-2,5-diphenylfuran serves as a versatile building block in organic synthesis, allowing chemists to create a wide range of compounds with diverse properties. Its reactivity and structural features make it an essential component in the synthesis of various organic compounds.
Used in Research and Development:
BDPF is used as a subject of research in various scientific fields, including medicinal chemistry and materials science. Its potential biological activities and the exploration of its derivatives as drug candidates make it a valuable compound for further investigation and development.

Upstream product

• 92874-20-9 4-bromo-4-nitro-1,4-diphenyl-butan-1-one 
• 79881-29-1 2-bromo-1,4-diphenyl-2-butene-1,4-dione 
• 63104-99-4 2-bromo-1,4-diphenyl-1,4-butanedione 
• 7664-93-9 sulfuric acid 
• 108-24-7 acetic anhydride 
• 768-03-6 Phenyl vinyl ketone 
• 55490-02-3 2-bromo-4-nitro-1,3-diphenyl-butan-1-one 
• 6277-65-2 (2-nitro-3-phenyl-cyclopropyl)-phenyl ketone 
• 92963-42-3 4-nitro-1,4-diphenyl-butan-1-one 
• 936-59-4 3-chloropropiophenone 
• 955-83-9 2,5-diphenylfuran 
• 64-19-7 acetic acid 
• 855624-42-9 4-bromo-3-nitro-1,4-diphenyl-butan-1-one 

Downstream Products

• 101576-05-0 3-bromo-4-bromomethyl-2,5-diphenyl-furan 
• 29113-75-5 2,5-diphenyl-furan-3-carboxylic acid 
• 79881-29-1 2-bromo-1,4-diphenyl-but-2c-ene-1,4-dione 
• 18830-03-0 1,1'-diphenyl-1H,1'H-4,4'-bipyrazole 
• 2132-80-1 4,4'-Dimethoxybiphenyl 
• 52107-61-6 2,2',5,5'-tetraphenyl-3,3'-bifuran 
• 36846-09-0 3-(4-methoxyphenyl)-2,5-diphenylfuran 
• 855613-92-2 2-diazo-1-(2,5-diphenyl-[3]furyl)-ethanone 
• 854704-35-1 2,5-diphenyl-furan-3-carbonyl chloride 

Relevant articles and documents

In-Depth Assessment of the Palladium-Catalyzed Fluorination of Five-Membered Heteroaryl Bromides

A thorough investigation of the challenging Pd-catalyzed fluorination of five-membered heteroaryl bromides is presented. Crystallographic studies and density functional theory (DFT) calculations suggest that the challenging step of this transformation is

Reaction of furans with trithiazyl trichloride: A new synthesis of isothiazoles

Trithiazyl trichloride 1 converts 2,5-diphenylfuran into 5-benzoyl-3-phenylisothiazole 2 regiospecifically and in high yield. This is a new ring opening of furans and a new synthesis of isothiazoles. 2,5-Bis(4-methylphenyl)furan, 3-bromo-2,5-diphenylfuran, 2,3,5-triphenylfuran, 2,5-di-tert-butylfuran and its 3-chloro and 3-bromo derivatives react in an entirely analogous manner to give the corresponding isothiazoles (55-85%) in synthetically useful, one-pot, conversions. 2,5-Diphenylthiophene reacts more slowly with the trimer 1 to give the same product, 2, as the corresponding furan, probably by oxidation of the analogous thiobenzoyl compound by the reagent, which is shown to oxidise thiobenzophenone to benzophenone very rapidly. Tetraphenylcyclopentadienone 8 reacts rapidly with the trimer to give 3,4,5,6-tetraphenyl-2(1H)-pyridone 10 (56%). Possible mechanisms in which the monomer, Cl-S≡N, is the reacting species are proposed for all of these reactions.