149353-71-9

Basic information

• Product Name: 2-(TERT-BUTOXYCARBONYL)ISOINDOLINE-5-CARBOXYLIC ACID
• Synonyms: 2-(TERT-BUTOXYCARBONYL)ISOINDOLINE-5-CARBOXYLIC ACID;2-Boc-1,3-dihydro-isoindole-5-carboxylic acid;2-[(tert-Butoxy)carbonyl]-2,3-dihydro-1H-isoindole-5-carboxylicacid
• CAS NO: 149353-71-9
• Molecular Formula: C₁₄H₁₇NO₄
• Molecular Weight: 263.29
• Mol File: 149353-71-9.mol

Chemical Properties

• Boiling Point: 412.1±45.0 °C(Predicted)
• Appearance: /
• Density: 1.257±0.06 g/cm3(Predicted)
• PKA: 4.39±0.20(Predicted)
• CAS DataBase Reference: 2-(TERT-BUTOXYCARBONYL)ISOINDOLINE-5-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(TERT-BUTOXYCARBONYL)ISOINDOLINE-5-CARBOXYLIC ACID(149353-71-9)
• EPA Substance Registry System: 2-(TERT-BUTOXYCARBONYL)ISOINDOLINE-5-CARBOXYLIC ACID(149353-71-9)

Safety Data

• Hazardous Substances Data: 149353-71-9(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
2-(TERT-BUTOXYCARBONYL)ISOINDOLINE-5-CARBOXYLIC ACID is used as a protecting group for amines and other reactive functional groups in organic synthesis. Its stability and mild removal conditions make it an ideal choice for protecting these groups during chemical reactions.
Used in Pharmaceutical Production:
2-(TERT-BUTOXYCARBONYL)ISOINDOLINE-5-CARBOXYLIC ACID is utilized in the production of pharmaceuticals, where its protective properties can be employed to shield reactive functional groups during the synthesis of complex drug molecules.
Used in Agrochemical Production:
2-(TERT-BUTOXYCARBONYL)ISOINDOLINE-5-CARBOXYLIC ACID is also used in the production of agrochemicals, where its protective capabilities can be applied to create more stable and effective products for agricultural use.
Used in Research and Development:
In the realm of research and development, this compound is employed for the exploration and creation of new chemical compounds, where its protective properties can be leveraged to facilitate the synthesis of novel molecules with potential applications in various industries.

Upstream product

• 6941-75-9 5-Bromoisoindoline-1,3-dione 
• 127168-94-9 methyl 2,3-dihydro-2-(phenylmethyl)-1H-isoindole-5-carboxylate 
• 691-64-5 di-tert-butyl oxalate 
• 1203600-37-6 2-tert-butyl 5-ethyl 1,3-dihydro-2H-isoindole-2,5-dicarboxylate 
• 201940-08-1 5-bromo-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 368441-44-5 2-(tert-butyl) 5-methyl isoindoline-2,5-dicarboxylate 

Downstream Products

• 1035216-60-4 tert-butyl 5-(3-(3-chloro-4-isopropoxyphenyl)-1,2,4-oxadiazol-5-yl)isoindoline-2-carboxylate 
• 685565-60-0 N-[4-(3-piperidin-1-ylpropoxy)benzoyl]-5-cyanoisoindoline 
• 263888-56-8 tert-butyl 5-cyanoisoindoline-2-carboxylate 

Relevant articles and documents

HETEROCYCLIC COMPOUND

The problem of the present invention is to provide a compound having a superior RORγt inhibitory action, and useful as a prophylactic or therapeutic agent for psoriasis, inflammatory bowel disease, ulcerative colitis, Crohn's disease, rheumatoid arthritis, multiple sclerosis, uveitis, asthma, ankylopoietic spondylarthritis, systemic lupus erythematosus, chronic obstructive pulmonary disease or the like. The present invention relates to a compound represented by the formula (I): [wherein each symbol is as described in the DESCRIPTION] or a salt thereof, which has an RORγt inhibitory action, and useful as a prophylactic or therapeutic agent for psoriasis, inflammatory bowel disease, ulcerative colitis, Crohn's disease, rheumatoid arthritis, multiple sclerosis, uveitis, asthma, ankylopoietic spondylarthritis, systemic lupus erythematosus, chronic obstructive pulmonary disease or the like.

AMIDINE DERIVATIVE

Provision of a novel amidine derivative or a pharmaceutically acceptable salt thereof having an activated blood coagulation factor X-inhibitory activity. A compound represented by the formula (I) wherein each symbol is as defined above, or a pharmaceutically acceptable salt thereof.

BICYCLIC BENZAMIDE COMPOUNDS AS HISTAMINE H3 RECEPTOR LIGAND USEFUL IN THE TREATMENT OF NEUROLOGICAL DISEASES

The present invention relates to novel bicyclic benzamide derivatives having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of neurological and psychiatric disorders.