14952-05-7 Usage
Uses
Used in Pharmaceutical Synthesis:
(2E)-non-2-enamide is used as a key intermediate in the synthesis of pharmaceuticals for its versatile chemical properties, contributing to the development of new drugs with potential therapeutic benefits.
Used as a Flavoring Agent in the Food Industry:
(2E)-non-2-enamide is utilized as a flavoring agent to enhance the taste and aroma of food products, leveraging its unique chemical composition to create desirable sensory experiences for consumers.
Used in Agricultural Products:
(2E)-non-2-enamide is used as an insect repellent in agricultural applications, providing a natural alternative to chemical pesticides for protecting crops from pests and improving overall yield.
Used in Cosmetic Products:
In the cosmetic industry, (2E)-non-2-enamide is employed for its insect repellent properties, offering consumers protection against insect bites and reducing the risk of insect-borne diseases.
Used in Medicinal Chemistry Research:
(2E)-non-2-enamide is being investigated for its potential as a bioactive compound with anti-inflammatory and anti-tumor properties, making it a promising candidate for further research and development in the field of medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 14952-05-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,9,5 and 2 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 14952-05:
(7*1)+(6*4)+(5*9)+(4*5)+(3*2)+(2*0)+(1*5)=107
107 % 10 = 7
So 14952-05-7 is a valid CAS Registry Number.
14952-05-7Relevant articles and documents
Solid phase synthesis of alkenes using the Horner-Wadsworth-Emmons reaction and monitoring by gel phase 31P NMR
Johnson,Zhang
, p. 9253 - 9256 (1995)
Phosphonoacetamide esters bound to solid supported peptides or peptide synthesis supports are active as Horner-Wadsworth-Emmons (HWE) reagents with a variety of aldehydes. HWE reagents can be attached to the solid support via the amide or phosphono ester. Mild basic conditions, triethylamine and Li salts, with excess aldehyde give high conversions to alkenes.
Direct substitution of primary allylic amines with sulfinate salts
Wu, Xue-Song,Chen, Yan,Li, Man-Bo,Zhou, Meng-Guang,Tian, Shi-Kai
supporting information, p. 14694 - 14697 (2012/11/07)
The NH2 group in primary allylic amines was substituted directly by sulfinate salts with excellent regio- and stereoselectivities. In the presence of 0.1 mol % [Pd(allyl)Cl]2, 0.4 mol % 1,4- bis(diphenylphosphino)butane (dppb), and excess boric acid, a range of α-unbranched primary allylic amines were smoothly substituted with sodium sulfinates in an α-selective fashion to give structurally diverse allylic sulfones in good to excellent yields with exclusive E selectivity. Replacing dppb with 1,1′-bi-2-naphthol (BINOL) allowed unsymmetric α-chiral primary allylic amines to be transformed into the corresponding allylic sulfones in good to excellent yields with excellent retention of ee. Importantly, the reaction complements known asymmetric methods in substrate scope via its unique ability to provide α-chiral allylic sulfones with high optical purity starting from unsymmetric allylic electrophiles.
