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2-Amino-5-isopropyl-thiophene-3-carboxylic acid methyl ester, with the molecular formula C10H15NO2S, is a methyl ester derivative of 2-amino-5-isopropyl-thiophene-3-carboxylic acid. This chemical compound is widely utilized in organic synthesis and pharmaceutical research due to its versatile chemical properties and potential applications in the development of new drugs and medications.

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  • 3-Thiophenecarboxylic acid, 2-amino-5-(1-methylethyl)-, methyl ester

    Cas No: 149587-85-9

  • USD $ 1.9-2.9 / Gram

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  • 149587-85-9 Structure
  • Basic information

    1. Product Name: 2-AMINO-5-ISOPROPYL-THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER
    2. Synonyms: 2-AMINO-5-ISOPROPYL-THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER;AKOS B000751;METHYL 2-AMINO-5-ISOPROPYL-3-THIOPHENECARBOXYLATE;ART-CHEM-BB B000751;TIMTEC-BB SBB009957;Methyl 2-amino-5-isopropylthiophene-3-carboxylate
    3. CAS NO:149587-85-9
    4. Molecular Formula: C9H13NO2S
    5. Molecular Weight: 199.27
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 149587-85-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 307.0±42.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.178±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 0.38±0.10(Predicted)
    10. CAS DataBase Reference: 2-AMINO-5-ISOPROPYL-THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-AMINO-5-ISOPROPYL-THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER(149587-85-9)
    12. EPA Substance Registry System: 2-AMINO-5-ISOPROPYL-THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER(149587-85-9)
  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 149587-85-9(Hazardous Substances Data)

149587-85-9 Usage

Uses

Used in Pharmaceutical Research:
2-Amino-5-isopropyl-thiophene-3-carboxylic acid methyl ester is used as a key intermediate in the synthesis of various heterocyclic compounds with potential biological activities. Its unique structure allows for the development of new drugs and medications, particularly for the treatment of certain neurological and psychiatric disorders.
Used in Organic Synthesis:
In the field of organic synthesis, 2-Amino-5-isopropyl-thiophene-3-carboxylic acid methyl ester serves as a building block for the creation of complex organic molecules. Its reactivity and functional groups make it a valuable component in the synthesis of a wide range of compounds.
Used in Antimicrobial Applications:
2-Amino-5-isopropyl-thiophene-3-carboxylic acid methyl ester has been studied for its potential antimicrobial properties. It can be used as an antimicrobial agent in various applications, such as in the development of new antibiotics or as a preservative in different industries.
Used in Anticancer Research:
2-AMINO-5-ISOPROPYL-THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER has also been investigated for its potential anticancer properties. It can be used as a starting material in the development of novel anticancer drugs, targeting specific cancer cells and exhibiting therapeutic effects.
Used in Medicinal Chemistry:
2-Amino-5-isopropyl-thiophene-3-carboxylic acid methyl ester is a versatile and valuable chemical in the field of medicinal chemistry. Its diverse applications, from drug development to antimicrobial and anticancer research, make it an essential component in the advancement of medical treatments and therapies.

Check Digit Verification of cas no

The CAS Registry Mumber 149587-85-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,9,5,8 and 7 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 149587-85:
(8*1)+(7*4)+(6*9)+(5*5)+(4*8)+(3*7)+(2*8)+(1*5)=189
189 % 10 = 9
So 149587-85-9 is a valid CAS Registry Number.

149587-85-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-amino-5-isopropylthiophene-3-carboxylic acid methyl ester

1.2 Other means of identification

Product number -
Other names methyl 2-amino-5-isopropylthiophene-3-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:149587-85-9 SDS

149587-85-9Relevant articles and documents

Microwave-assisted synthesis of 2-aminothiophene derivatives via improved gewald reactions

Ruan, Bankang,Zhang, Zhiyan,Huang, Lei,Xu, Chao,Li, Luolan

, p. 2007 - 2018 (2021/09/29)

In this paper, a new and efficient method was developed to prepare 2-aminothiophene derivatives through improved Gewald reaction. Thirty-one final products were synthesized under microwave radiation for 30 min with 57%-95% isolated yields. All the product

Discovery of novel thieno[2,3-d]pyrimidin-4-yl hydrazone-based inhibitors of Cyclin D1-CDK4: Synthesis, biological evaluation, and structure-activity relationships

Horiuchi, Takao,Chiba, Jun,Uoto, Kouichi,Soga, Tsunehiko

scheme or table, p. 305 - 308 (2011/02/28)

The synthesis and evaluation of new analogues of thieno[2,3-d]pyrimidin-4-yl hydrazones are described. 2-Pyrdinecarboxaldehyde [6-(tert-butyl)thieno[2,3-d]pyrimidine-4-yl]hydrazone derivatives have been identified as cyclin-dependent kinase 4 (CDK4) inhibitors. The potency, selectivity profile, and structure-activity relationship of this series of compounds are discussed.

THIENO [2,3-D] PYRIMIDINE COMPOUNDS AS INHIBITORS OF ADP-MEDIATED PLATELETS AGGREGATION

-

Page/Page column 95, (2008/06/13)

Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula (I): wherein A1, A2, A3, A4, A5, A6, A7, A8, X4, X6, R2, R4, R5, and R6 are as defined in the detailed description of the invention. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

Thieno pyrazine diones, their preparation and use

-

, (2008/06/13)

Novel thieno[2,3-b]pyrazine-2,3(1H,3H)-diones or tautomeric forms thereof of the formula (I) STR1 The compounds are useful in the treatment of neurological and psychiatric diseases.

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