149739-65-1

Basic information

• Product Name: 5-(3-BROMO-PHENYL)-1H-PYRAZOLE
• Synonyms: 5-(3-BROMO-PHENYL)-1H-PYRAZOLE;3-(3-bromophenyl)-1H-pyrazol;1-Bromo-3-(1H-pyrazol-3-yl)benzene
• CAS NO: 149739-65-1
• Molecular Formula: C₉H₇BrN₂
• Molecular Weight: 223.07
• Product Categories: Phenyls & Phenyl-Het;Halides;Phenyls & Phenyl-Het;Building Blocks;C9;Chemical Synthesis;Halogenated Heterocycles;Heterocyclic Building Blocks;Pyrazoles
• Mol File: 149739-65-1.mol

Chemical Properties

• Melting Point: 71-75℃
• Boiling Point: 375.6 °C at 760 mmHg
• Flash Point: 181 °C
• Appearance: /
• Density: 1.565g/cm³
• Vapor Pressure: 1.66E-05mmHg at 25°C
• Refractive Index: 1.635
• Storage Temp.: 2-8°C
• PKA: 13.28±0.10(Predicted)
• CAS DataBase Reference: 5-(3-BROMO-PHENYL)-1H-PYRAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(3-BROMO-PHENYL)-1H-PYRAZOLE(149739-65-1)
• EPA Substance Registry System: 5-(3-BROMO-PHENYL)-1H-PYRAZOLE(149739-65-1)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• RIDADR: UN 2811
• WGK Germany: 3
• Hazardous Substances Data: 149739-65-1(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
5-(3-BROMO-PHENYL)-1H-PYRAZOLE is used as a key intermediate in the synthesis of various organic compounds. Its unique structure allows it to participate in a range of reactions, making it a valuable component in the creation of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 5-(3-BROMO-PHENYL)-1H-PYRAZOLE is used as a potential drug candidate for the development of new medications. Its pharmaceutical properties have been studied, and it is being explored for its potential therapeutic applications, including the treatment of various diseases and conditions.
Used in Research and Development:
5-(3-BROMO-PHENYL)-1H-PYRAZOLE is also utilized in research and development settings to investigate its chemical properties, reactivity, and potential applications in various fields. This includes studying its interactions with other compounds and understanding its role in chemical reactions, which can contribute to the advancement of scientific knowledge and the development of innovative products.

InChI:InChI=1/C9H7BrN2/c10-8-3-1-2-7(6-8)9-4-5-11-12-9/h1-6H,(H,11,12)

Upstream product

• 1428581-88-7 (Z)-1-(3-bromophenyl)-3-(dimethylamino)prop-2-en-1-one 
• 2142-63-4 1-(3-Bromophenyl)ethanone 

Downstream Products

• 1428581-98-9 tert-butyl (1-(2-(3-(1H-pyrazol-3-yl)phenyl)-5-fluoropyrimidin-4-yl)piperidin-4-yl)methylcarbamate 
• 1217340-87-8 3-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1H-pyrazole 
• 1373254-11-5 3-(3-(3-bromophenyl)-1H-pyrazol-1-yl)-1,3-diphenylpropan-1-one 
• 1268613-68-8 C₁₈H₁₅BrN₂O 
• 1217340-87-8 5-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1H-pyrazole 
• 1632071-01-2 C₁₆H₁₄N₂ 
• 1612156-05-4 tert-butyl 4-(3-(1H-pyrazol-5-yl)phenyl)piperidine-1-carboxylate 
• 1386231-70-4 potassium 3-(1H-pyrazol-5-yl)phenyltrifluoroborate 
• 1174304-73-4 (4-(1H-pyrazol-5-yl)phenyl)boronic acid 
• 1311285-12-7 C₂₂H₂₈N₄ 
• 1311286-89-1 C₂₁H₂₇N₅ 
• 1311285-11-6 1-methyl-3-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-1H-pyrazole 
• 425379-68-6 3-(3-bromo-phenyl)-1-methyl-1H-pyrazole 

Relevant articles and documents

PYRIMIDINE PYRAZOLYL DERIVATIVES AND THEIR USE AS IRAK INHIBITORS

The present invention provides compounds of Formula (II) for the treatment of cancer, rheumatoid arthritis and other diseases.

PYRIMIDINE PYRAZOLYL DERIVATIVES AND THEIR USE AS IRAK INHIBITORS

The present invention provides compounds of Formula (II) for the treatment of cancer, rheumatoid arthritis and other diseases.

N-PIPERIDIN-4-YL DERIVATIVES

The invention relates to a N-piperidin-4-yl derivative having the general Formula I or a pharmaceutically acceptable salt thereof, to pharmaceutical compositions comprising the same and to the use of said N-piperidin-4-yl derivatives for the treatment and prevention of endometriosis, for the treatment and prevention of pre-menopausal and peri-menopausal hormone-dependent breast cancer, for contraception, or for the treatment of uterine fibroids or other menstrual-related disorders.