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150187-40-9

7α-(5-methanesulfonyloxypentyl)estradiol 3-benzyl ether is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 150187-40-9 Structure

  • Basic information

    1. Product Name: 7α-(5-methanesulfonyloxypentyl)estradiol 3-benzyl ether
    2. Synonyms: 7α-(5-methanesulfonyloxypentyl)estradiol 3-benzyl ether
    3. CAS NO:150187-40-9
    4. Molecular Formula:
    5. Molecular Weight: 526.737
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 150187-40-9.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 7α-(5-methanesulfonyloxypentyl)estradiol 3-benzyl ether(CAS DataBase Reference)
    10. NIST Chemistry Reference: 7α-(5-methanesulfonyloxypentyl)estradiol 3-benzyl ether(150187-40-9)
    11. EPA Substance Registry System: 7α-(5-methanesulfonyloxypentyl)estradiol 3-benzyl ether(150187-40-9)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 150187-40-9(Hazardous Substances Data)

150187-40-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 150187-40-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,0,1,8 and 7 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 150187-40:
(8*1)+(7*5)+(6*0)+(5*1)+(4*8)+(3*7)+(2*4)+(1*0)=109
109 % 10 = 9
So 150187-40-9 is a valid CAS Registry Number.

150187-40-9Relevant articles and documents

A synthesis of 7α-substituted estradiols: synthesis and biological evaluation of a 7α-pentyl-substituted BODIPY fluorescent conjugate and fluorine 18-labeled 7α-pentylestradiol analog

French, Andrew N.,Wilson, Scott R.,Welch, Michael J.,Katzenellenbogen, John A.

, p. 157 - 169 (2007/10/02)

In an effort to assist in the preparation of ligands for the study of the estrogen receptor (ER), we have developed a new synthesis of 7α-substituted estradiols.The key step in the synthesis involves a copper-catalyzed, α-selective, 1,6-conjugate addition of 4-pentenyl magnesium bromide to a suitably protected 6-dehydrotestosterone derivative.Desaturation and then reductive aromatization of the resulting 7α-pentenyl androgen gave the 7α-pentenylestradiol in good yields.The α-stereoselectivity of this addition in the testosterone series, compared with the 19-nortestosterone series, is significantly improved by the presense of the C-19 methyl group, which shields the beta face from attack.A key intermediate was functionalized further by substitution with fluorine-18 to provide a potential imaging agent for positron emission tomography, and by conjugation with a BODIPY (Molecular Probes Inc., Eugene, OR, USA fluorophore to make a fluorescent probe for the estrogen receptor.The synthesis and biological evaluation of these analogs is presented, as well as a discussion of the improvements in the synthetic procedure.Keywords: steroids; estrogen receptor; fluorescence; breast tumor imaging; fluorine-18; 7α-substituted estrogen

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