152536-39-5

Basic information

• Product Name: 1,4,5-triMethyl-2-phenyl-1H-iMidazole
• Synonyms: 1,4,5-triMethyl-2-phenyl-1H-iMidazole
• CAS NO: 152536-39-5
• Molecular Formula: C₁₂H₁₄N₂
• Molecular Weight: 186.25296
• EINECS: -0
• Mol File: 152536-39-5.mol

Chemical Properties

• Boiling Point: 343.4±45.0 °C(Predicted)
• Appearance: /
• Density: 1.02±0.1 g/cm3(Predicted)
• PKA: 7.44±0.60(Predicted)
• CAS DataBase Reference: 1,4,5-triMethyl-2-phenyl-1H-iMidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4,5-triMethyl-2-phenyl-1H-iMidazole(152536-39-5)
• EPA Substance Registry System: 1,4,5-triMethyl-2-phenyl-1H-iMidazole(152536-39-5)

Safety Data

• Hazardous Substances Data: 152536-39-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research:
1,4,5-triMethyl-2-phenyl-1H-iMidazole is used as a research compound for its potential anti-inflammatory and analgesic properties. Its unique structure and chemical properties allow it to be studied for the development of new drugs targeting inflammation and pain relief.
Used in Drug Development:
1,4,5-triMethyl-2-phenyl-1H-iMidazole is used as a lead compound in drug development for the treatment of inflammatory conditions and pain management. Its biological activity and structural features make it a valuable starting point for the design and synthesis of novel therapeutic agents.
Used in Medicinal Chemistry:
1,4,5-triMethyl-2-phenyl-1H-iMidazole is used as a building block in medicinal chemistry for the synthesis of new compounds with improved pharmacological properties. Its versatile structure can be modified to create derivatives with enhanced potency, selectivity, and bioavailability.
Used in Chemical Synthesis:
1,4,5-triMethyl-2-phenyl-1H-iMidazole is used as a synthetic intermediate in the preparation of other organic compounds, particularly those with potential applications in the pharmaceutical and chemical industries. Its reactivity and functional groups make it a valuable component in the synthesis of complex molecules.

Upstream product

• 20185-22-2 1,4,5-Trimethylimidazole 
• 873-55-2 sodium benzenesulfonate 
• 100-52-7 benzaldehyde 

Relevant articles and documents

Cyclometalated iridium(III) complexes based on phenyl-imidazole ligand

Phenyl-imidazole-based ligands with various substitution patterns have been used as the main ligand for heteroleptic bis-cyclometalated iridium complexes. Two series of complexes have been prepared and their photophysical and electrochemical properties we

Palladium-catalyzed desulfitative C-H arylation of heteroarenes with sodium sulfinates

Desulfitative C-H arylation: Palladium-catalyzed desulfitative C-H arylation of heteroarenes with sodium sulfinates has been disclosed to construct aryl-heteroaryl bonds without the need for any extra ligands (see scheme). Copyright

Synthesis and single-crystal X-ray diffraction studies of new cyclometallated phenylimidazole palladium(II) compounds

Cyclometallation of 1,4,5-trimethyl-2-phenylimidazole, L, with Pd(OAc)2 gave exclusively the dinuclear anti isomer with bridging acetate ligands, 1. Subsequent treatment of 1 with sodium chloride gave the corresponding dinuclear compound with b

Synthesis of imidazoles via hetero-cope rearrangements

A novel synthetic approach to heterocycles containing the imidazole moiety based on the multihetero-Cope rearrangement is described. Oximes are reacted with benzenecarboximidoyl chlorides 4 affording adducts that readily undergo the hetero-Cope rearrangement at slightly elevated temperatures. Acid treatment of the resulting amidines 8 provides imidazoles in very high yields.