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(+)-3,4,4A,5,6,10B-HEXAHYDRO-9-METHOXY-2H-NAPHTHO[1,2-B][1,4]OXAZIN-3-ONE is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • (+)-3,4,4a,5,6,10b-Hexahydro-9-methoxy-2H-naphtho[1,2-b][1,4]oxazin-3-one

    Cas No: 153153-60-7

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  • (+)-3,4,4A,5,6,10B-HEXAHYDRO-9-METHOXY-2H-NAPHTHO[1,2-B][1,4]OXAZIN-3-ONE

    Cas No: 153153-60-7

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  • 153153-60-7 Structure
  • Basic information

    1. Product Name: (+)-3,4,4A,5,6,10B-HEXAHYDRO-9-METHOXY-2H-NAPHTHO[1,2-B][1,4]OXAZIN-3-ONE
    2. Synonyms: (-)-3,4,4A,5,6,10B-HEXAHYDRO-9-METHOXY-2H-NAPHTHO[1,2-B][1,4]OXAZIN-3-ONE;(+)-3,4,4A,5,6,10B-HEXAHYDRO-9-METHOXY-2H-NAPHTHO[1,2-B][1,4]OXAZIN-3-ONE;(4aR-trans)-4a,5,6,10b-Tetrahydro-9-Methoxy-2H-naphth[1,2-b]-1,4-oxazin-3(4H)-one
    3. CAS NO:153153-60-7
    4. Molecular Formula: C13H17NO2
    5. Molecular Weight: 219.28
    6. EINECS: N/A
    7. Product Categories: Chiral Reagents;Neurochemicals
    8. Mol File: 153153-60-7.mol
  • Chemical Properties

    1. Melting Point: 216-218°C
    2. Boiling Point: 468.7±45.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.191±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: -20°C Freezer
    8. Solubility: Dichloromethane, Ethyl Acetate, Methanol
    9. PKA: 13.95±0.20(Predicted)
    10. CAS DataBase Reference: (+)-3,4,4A,5,6,10B-HEXAHYDRO-9-METHOXY-2H-NAPHTHO[1,2-B][1,4]OXAZIN-3-ONE(CAS DataBase Reference)
    11. NIST Chemistry Reference: (+)-3,4,4A,5,6,10B-HEXAHYDRO-9-METHOXY-2H-NAPHTHO[1,2-B][1,4]OXAZIN-3-ONE(153153-60-7)
    12. EPA Substance Registry System: (+)-3,4,4A,5,6,10B-HEXAHYDRO-9-METHOXY-2H-NAPHTHO[1,2-B][1,4]OXAZIN-3-ONE(153153-60-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 153153-60-7(Hazardous Substances Data)

153153-60-7 Usage

Chemical Properties

Beige Powder

Uses

A dopamine antagonist. A dopaminergic ligand

Check Digit Verification of cas no

The CAS Registry Mumber 153153-60-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,3,1,5 and 3 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 153153-60:
(8*1)+(7*5)+(6*3)+(5*1)+(4*5)+(3*3)+(2*6)+(1*0)=107
107 % 10 = 7
So 153153-60-7 is a valid CAS Registry Number.

153153-60-7Downstream Products

153153-60-7Relevant articles and documents

Synthesis and pharmacological activity of the hexahydro-4H-naphth[1,2b][1,4]-oxazines: A new series of potent dopamine receptor agonists

Dykstra,Hazelhoff,Mulder,et al.

, p. 247 - 250 (2007/10/02)

The synthesis in 8 steps of a new series of potent dopamine (DA) agonists, the trans-hexahydro-4H-naphth[1,2b][1,4]oxazines, is described. The yields of all steps are good to excellent. The dopaminergic activity of these new compounds was evaluated in rats in three test systems, i.e. for the ability to displace the specific in vitro binding of [3H]-DPAT to rat brain striatal homogenates for the effects on DA metabolism in the corpus striatum and for their ability to induce stereotypy. The activity of trans-N-n-propyl-9-hydroxy-2,3,4a,5,6,10b-hexahydro-4H-naphth[1,2b][1,4] oxazine (N-0500) was found to be comparable to that of the known potent DA agonist RU 29717.

Synthesis of 4-substituted 2H-naphth[1,2-b]-1,4-oxazines, a new class of dopamine agonists

Jones,Anderson,Baldwin,Clineschmidt,McClure,Lundell,Randall,Martin,Williams,Hirshfield

, p. 1607 - 1613 (2007/10/02)

A series of tricyclic oxazines, namely, the 4-substituted 2H-naphth[1,2-b]-1,4-oxazines, have been synthesized and assayed for dopamine agonist activity. One of the members of this series was found to be a remarkably potent agonist in vivo when tested in

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