15469-97-3

Basic information

• Product Name: 1-(Triphenylmethyl)imidazole
• Synonyms: N-TRITYLIMIDAZOLE;(TRIPHENYLMETHYL)IMIDAZOLE;1-(TRIPHENYLMETHYL)IMIDAZOLE;1-TRITYL-1H-IMIDAZOLE;1-TRITYLIMIDAZOLE;N-(Triphenylmethyl)imidazole;CDD 3501;ClotriMazole IMpurity F
• CAS NO: 15469-97-3
• Molecular Formula: C₂₂H₁₈N₂
• Molecular Weight: 310.39
• EINECS: -0
• Product Categories: blocks;Imidazoles;Building Blocks;Heterocyclic Building Blocks;Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks;Amines;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 15469-97-3.mol

Chemical Properties

• Melting Point: 220-224 °C(lit.)
• Boiling Point: 451.294 °C at 760 mmHg
• Flash Point: 226.734 °C
• Appearance: /
• Density: 1.058 g/cm³
• Vapor Pressure: 6.57E-08mmHg at 25°C
• Refractive Index: 1.606
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: DMSO (Slightly, Sonicated), Methanol (Slightly, Sonicated)
• PKA: 6.34±0.30(Predicted)
• Water Solubility: Insoluble in water.
• BRN: 238171
• CAS DataBase Reference: 1-(Triphenylmethyl)imidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(Triphenylmethyl)imidazole(15469-97-3)
• EPA Substance Registry System: 1-(Triphenylmethyl)imidazole(15469-97-3)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 15469-97-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1-(Triphenylmethyl)imidazole is used as an antifungal agent for its Clotrimazole (C587400) analog properties. It demonstrates potent antifungal activity against a range of fungal pathogens, making it a valuable compound in the development of new antifungal drugs and treatments.
Used in Chemical Synthesis:
1-(Triphenylmethyl)imidazole is used as a key intermediate in the synthesis of 1,2,5-trisubstituted imidazole derivatives. These derivatives have a wide range of applications, including pharmaceuticals, agrochemicals, and materials science. The unique structural features of 1-(Triphenylmethyl)imidazole enable the efficient synthesis of these valuable compounds, contributing to the advancement of various industries.

InChI:InChI=1/C22H18N2/c1-4-10-19(11-5-1)22(24-17-16-23-18-24,20-12-6-2-7-13-20)21-14-8-3-9-15-21/h1-18H

Upstream product

• 288-32-4 1H-imidazole 
• 87268-78-8 2-trityl-5-phenyl-2H-tetrazole 
• 76-84-6 triphenylmethyl alcohol 
• 596-43-0 bromo-triphenyl-methane 
• 1252858-34-6 4-amino-5-iodo-7-[2,3,5-tris-O-(tert-butyldimethylsilyl)-β-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidine 
• 96797-15-8 N-trityl-4⁽⁵⁾-iodoimidazole 
• 102-10-3 diphenyl phosphite 
• 119-61-9 benzophenone 
• 108-86-1 bromobenzene 
• 76-83-5 trityl chloride 
• 68-12-2 N,N-dimethyl-formamide 
• 28697-53-2 D-arabinopyranose 
• 3473-63-0 formamidine acetic acid 
• 95953-45-0 triphenylmethyl 4-cyanophenyl ether 

Downstream Products

• 67478-50-6 1-(triphenylmethyl)-1H-imidazole-2-carboxaldehyde 
• 37594-47-1 1-(4,4',4''-trichloro-trityl)-1H-imidazole 
• 873215-54-4 4-hydroxy-4-(1-trityl-1H-imidazol-2-yl)-piperidine-1-carboxylic acid ethyl ester 
• 399508-38-4 (1S,2R)-2-Benzyloxy-2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-(1-trityl-1H-imidazol-2-yl)-ethanol 
• 399508-39-5 (1R,2R)-2-Benzyloxy-2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-(1-trityl-1H-imidazol-2-yl)-ethanol 
• 399508-60-2 (1S,2S)-2-Benzyloxy-2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-(1-trityl-1H-imidazol-2-yl)-ethanol 
• 399508-59-9 (1R,2S)-2-Benzyloxy-2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-(1-trityl-1H-imidazol-2-yl)-ethanol 
• 399508-50-0 (1S,2R)-2-Benzyloxy-2-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-(1-trityl-1H-imidazol-2-yl)-ethanol 
• 399508-51-1 (1R,2R)-2-Benzyloxy-2-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-(1-trityl-1H-imidazol-2-yl)-ethanol 
• 399508-30-6 (1S,2S)-2-Benzyloxy-2-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-(1-trityl-1H-imidazol-2-yl)-ethanol 
• 399508-29-3 (1R,2S)-2-Benzyloxy-2-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-(1-trityl-1H-imidazol-2-yl)-ethanol 
• 288573-59-1 2-indolyl-N-trityl-2-imidazolyl ketone 
• 211488-48-1 1-(1-Trityl-1H-imidazol-2-yl)-2-trityloxy-ethanol 
• 189948-97-8 (S)-1-[(1-triphenylmethyl)-imidazol-2-yl]-propan-2-ol 

Relevant articles and documents

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