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Tetrahydro-pyridazine-1-carboxylic acid tert-butyl ester is a versatile organic chemical compound belonging to the class of pyridazine carboxylic acids and derivatives. It is a derivative of pyridazine carboxylic acid, characterized by its tetrahydro structure and tert-butyl ester group, which enhances its stability and suitability for use in various organic reactions. Tetrahydro-pyridazine-1-carboxylic acid tert-butyl ester serves as a valuable intermediate in the synthesis of pharmaceutical and agrochemical compounds and as a building block for the creation of diverse heterocyclic compounds.

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  • 154972-37-9 Structure
  • Basic information

    1. Product Name: Tetrahydro-pyridazine-1-carboxylic acid tert-butyl ester
    2. Synonyms: Tetrahydro-pyridazine-1-carboxylic acid tert-butyl ester;Tert-Butyl Tetrahydro-1(2H)-Pyridazinecarboxylate(WX604650)
    3. CAS NO:154972-37-9
    4. Molecular Formula: C9H18N2O2
    5. Molecular Weight: 186
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 154972-37-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Tetrahydro-pyridazine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
    10. NIST Chemistry Reference: Tetrahydro-pyridazine-1-carboxylic acid tert-butyl ester(154972-37-9)
    11. EPA Substance Registry System: Tetrahydro-pyridazine-1-carboxylic acid tert-butyl ester(154972-37-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 154972-37-9(Hazardous Substances Data)

154972-37-9 Usage

Uses

Used in Pharmaceutical Industry:
Tetrahydro-pyridazine-1-carboxylic acid tert-butyl ester is used as a key intermediate in the synthesis of various pharmaceutical compounds for its ability to contribute to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, Tetrahydro-pyridazine-1-carboxylic acid tert-butyl ester is utilized as an intermediate in the production of agrochemicals, contributing to the development of effective pesticides and other agricultural chemicals to protect crops and enhance yield.
Used in Organic Synthesis:
Tetrahydro-pyridazine-1-carboxylic acid tert-butyl ester is used as a building block in organic synthesis for its ability to form diverse heterocyclic compounds, which are important in various chemical and pharmaceutical applications due to their unique properties and reactivity.
Used in Research and Development:
Tetrahydro-pyridazine-1-carboxylic acid tert-butyl ester is also used in research and development settings as a versatile chemical entity for exploring new reaction pathways, understanding structure-activity relationships, and discovering novel applications in various fields, including materials science and medicinal chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 154972-37-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,4,9,7 and 2 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 154972-37:
(8*1)+(7*5)+(6*4)+(5*9)+(4*7)+(3*2)+(2*3)+(1*7)=159
159 % 10 = 9
So 154972-37-9 is a valid CAS Registry Number.

154972-37-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl diazinane-1-carboxylate

1.2 Other means of identification

Product number -
Other names N-Boc-hexahydropyridazine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:154972-37-9 SDS

154972-37-9Relevant articles and documents

Peptidomimetic inhibitors of bacterial peptide deformylase

East, Stephen P.,Ayscough, Andrew,Toogood-Johnson, Ian,Taylor, Steven,Thomas, Wayne

, p. 4032 - 4035 (2011/08/06)

A series of N-formyl hydroxylamine peptide deformylase inhibitors containing a cyclic azaamino acid moiety between the P1′ and P3′ substituents are presented. Selected compounds display antibacterial activity against pathogens associated with respiratory

PYRAZOLE DERIVATIVES

-

Page/Page column 36, (2010/11/26)

A compound represented by formula (I): (wherein Ar1 represents a phenyl group which may have 1 to 3 substituents, or a non-substituted 5- or 6-membered aromatic heterocyclic group; Ar2 represents (i) a non-substituted phenyl group, (ii) a phenyl group which has been substituted by a lower alkyl group having 1 to 3 groups or atoms selected from among a carbamoyl group, an amino group, a hydroxyl group, a lower alkoxy group, and a halogen atom, or (iii) a 5- or 6-membered nitrogen-containing aromatic heterocyclic group which has been substituted by 1 to 3 groups or atoms selected from among a lower alkyl group, a lower alkynyl group, a lower alkanoyl group, a carbamoyl group, a cyano group, an amino group, a hydroxyl group, a lower alkoxy group, and a halogen atom; and X represents a group represented by formula (II): (wherein the ring structure represents a 4- to 7-membered heterocyclic group which may have, in addition to the nitrogen atom shown in formula (II), one heteroatom selected from among nitrogen, oxygen, and sulfur, and which may be substituted by 1 to 4 groups or atoms selected from among a lower alkyl group, a carbamoyl group, an amino group, a hydroxyl group, a lower alkoxy group, an oxo group, a lower alkanoyl group, a lower alkylsulfonyl group, and a halogen atom)), a salt thereof, a solvate of the compound or the salt, and a drug.

PYRAZOLE DERIVATIVE

-

Page/Page column 42, (2010/11/27)

A compound represented by Formula (I): wherein Ar1 represents Formula (II): Ar2 represents a 5- or 6-membered aromatic heterocyclic group which may be substituted; and X represents Formula (III): a salt thereof, or a solvate of the compound or the salt. A potent platelet aggregation suppressant which does not inhibit COX-1 and COX-2 is provided.

Novel compounds and therapeutic uses thereof

-

Page 25, (2010/02/03)

The invention discloses a novel series of compound represented by general formula (I), its derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, pharmaceutically acceptable salts, solvates wherein X, n, k, z, R1, R2, R3, R4, R5 and R6 are as defined in the specification that are useful in (i) normalizing elevated blood glucose levels in diabetes, (ii) treating disorders related to glucose intolerance and (iii) for scavenging free radicals of mammals. The invention also discloses pharmaceutically acceptable composition comprising these compounds, method for preparation of the compounds as defined above and method of treating mammals including human beings by administering an effective amount of said compounds to a subject in need thereof. The invention further discloses use of these compounds in the manufacture of a medicament useful for treatment of different disease conditions as stated above.

Cyclic dibenzoylhydrazines reproducing the conformation of ecdysone agonists, RH-5849

Toya, Tetsuya,Yamaguchi, Kentaro,Endo, Yasuyuki

, p. 953 - 961 (2007/10/03)

We have investigated the biologically active conformation of the non-steroidal ecdysone agonist, 1-tert-butyl-1,2-dibenzoylhydrazine (RH-5849) by means of design, synthesis and conformational analysis of cyclic derivatives of RH-5849. Among the synthesize

Azapeptide acids as cell adhesion inhibitors

-

, (2008/06/13)

Azapeptide acids of Formula I are antagonists of VLA-4 and/or alpha 4 beta 7, and as such are useful in the inhibition or prevention of cell adhesion and cell-adhesion mediated pathologies. These compounds may be formulated into pharmaceutical composition

Quinaldoyl-amine derivatives of oxo-and hydroxy-substituted hydrocarbons

-

, (2008/06/13)

The present invention discloses the compounds of general formula (1) STR1 wherein R1, R2, R3 are optionally substituted carbonyl and amide derivatives which are useful as inhibitors of retroviral proteases, and are effecti

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