158890-30-3

Basic information

• Product Name: Piperidine, 1-(chloroacetyl)-4,4-dimethyl- (9CI)
• Synonyms: Piperidine, 1-(chloroacetyl)-4,4-dimethyl- (9CI)
• CAS NO: 158890-30-3
• Molecular Formula: C₉H₁₆ClNO
• Molecular Weight: 189.68244
• Product Categories: ACETYLHALIDE
• Mol File: 158890-30-3.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Piperidine, 1-(chloroacetyl)-4,4-dimethyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Piperidine, 1-(chloroacetyl)-4,4-dimethyl- (9CI)(158890-30-3)
• EPA Substance Registry System: Piperidine, 1-(chloroacetyl)-4,4-dimethyl- (9CI)(158890-30-3)

Safety Data

• Hazardous Substances Data: 158890-30-3(Hazardous Substances Data)

Upstream product

• 38646-68-3 4,4-dimethylpiperidine hydrochloric acid salt 
• 79-04-9 chloroacetyl chloride 
• 1123-40-6 3,3-dimethyl glutarimide 

Downstream Products

• 907209-58-9 C₁₆H₂₂N₂O₅ 

Relevant articles and documents

INHIBITORS OF SERINE PALMITOYLTRANSFERASE

This invention provides compounds of the formula (I) useful in the inhibition or modulation of serine palmitoyl transferase and their use in methods of treatment or amelioration of type 2 diabetes, type 1 diabetes, insulin resistance, the effects of obesity, metabolic syndrome (sometimes referred to as Syndrome X), impaired glucose tolerance, Cushing's disease, cardiovascular disease, prothrombotic conditions, myocardial infarction, hypertension, congestive heart failure, cardiomyopathy, atherosclerosis, dyslipidemia, sepsis, liver damage, retinal degenerative disorders, cachexia, emphysema, hepatitis C infections, HIV infections and inflammatory disorders and useful in methods for raising HDL plasma levels in a mammal. The compounds of this invention can also be used to prevent damage or loss of pancreatic islet beta cells (such as in the case of pancreatic beta cell apoptosis, including those related to insulin-dependent diabetes mellitus).

BENZOTHIAZEPINE AND BENZOXAZEPINE DERIVATIVES AS CHOLECYSTOKININ RECEPTOR ANTAGONISTS

The present invention relates to novel substituted benzothiazepines and benzoxazepines of the formula STR1 wherein R 1, R 2, R. sup. 7, R 8, R 9 and X are as defined below, and to novel intermediates used in the synthesis of such compounds. Such compounds are useful in the treatment and prevention of gastrointestinal disorders, pain and anxiety disorders.