159533-68-3

Basic information

• Product Name: 1-(5-BROMOPYRIDIN-2-YL)-ETHANOL
• Synonyms: 1-(5-BROMOPYRIDIN-2-YL)-ETHANOL;2-Pyridinemethanol,5-bromo-α-methyl-
• CAS NO: 159533-68-3
• Molecular Formula: C7H8BrNO
• Molecular Weight: 202.05
• Product Categories: pharmacetical
• Mol File: 159533-68-3.mol

Chemical Properties

• Boiling Point: 274.4°Cat760mmHg
• Flash Point: 119.8°C
• Appearance: /
• Density: 1.555g/cm³
• Vapor Pressure: 0.00263mmHg at 25°C
• Refractive Index: 1.578
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 1-(5-BROMOPYRIDIN-2-YL)-ETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(5-BROMOPYRIDIN-2-YL)-ETHANOL(159533-68-3)
• EPA Substance Registry System: 1-(5-BROMOPYRIDIN-2-YL)-ETHANOL(159533-68-3)

Safety Data

• Hazardous Substances Data: 159533-68-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1-(5-Bromopyridin-2-yl)-ethanol is used as a building block for the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 1-(5-Bromopyridin-2-yl)-ethanol is utilized as a key component in the creation of agrochemicals, contributing to the development of effective and innovative products for agricultural use.
Used in Organic Chemistry Research:
As an intermediate in the production of other organic compounds, 1-(5-Bromopyridin-2-yl)-ethanol is employed in organic chemistry research to explore new reactions and syntheses, further expanding the understanding of organic chemistry and its applications.

InChI:InChI=1/C7H8BrNO/c1-5(10)7-3-2-6(8)4-9-7/h2-5,10H,1H3

Upstream product

• 159533-68-3 2-(1-hydroxyethyl)-5-bromopyridine 
• 31181-90-5 5-bromo-pyridine-2-carbaldehyde 
• 75-16-1 methylmagnesium bromide 
• 223463-13-6 2-iodo-5-bromopyridine 
• 75-07-0 acetaldehyde 
• 214701-49-2 1-(5-bromopyridin-2-yl)ethanone 
• 845305-87-5 5-bromo-2-(N-methylaminocarbonyl)pyridine 
• 30766-11-1 5-bromoisonicotinic acid 

Downstream Products

• 159533-68-3 (1R)-1-(5-bromopyridin-2-yl)ethanol 
• 159533-68-3 (1S)-1-(5-bromopyridin-2-yl)ethanol 
• 870694-29-4 2-bromo-1-(5-bromopyridin-2-yl)ethanone hydrobromide 
• 953780-20-6 (R)-1-(5-bromopyridin-2-yl)ethanamine 

Relevant articles and documents

Asymmetric Hydroboration of Heteroaryl Ketones by Aluminum Catalysis

A series of methyl aluminum complexes bearing chiral biphenol-type ligands were found to be highly active catalysts in the asymmetric reduction of heterocyclic ketones (S/C = 100-500, ee up to 99%). The protocol is suitable for a wide range of substrates and has a high tolerance to functional groups. The formed 2-heterocyclic-alcohols are valuable building blocks in drug discovery or can be used as ligands in asymmetric catalysis. Isolation and comprehensive characterization of the reaction intermediates support a catalysis cycle proposed by DFT calculations.

Straight from the bottle! Wine and juice dicarboxylic acids as templates for supramolecular cage self-assembly

Two imine based supramolecular cages are able to self-assemble in the presence of a complex mixture like wine or fruit juices. Taking advantage of templating agents present in these mixtures the systems are able to form and to selectively encapsulate dicarboxylic systems present in the mixtures. This capability has been exploited to develop molecular systems able to report the enantiomeric excess and composition of (a)chiral dicarboxylic acids in fruit juices and wines using 1H-NMR. This journal is

CONDENSED IMIDAZOLE DERIVATIVES SUBSTITUTED BY TERTIARY HYDROXY GROUPS AS PI3K-GAMMA INHIBITORS

This application relates to compounds of Formula (I): or pharmaceutically acceptable salts thereof, which are inhibitors of PI3K-y which are useful for the treatment of disorders such as autoimmune diseases, cancer, cardiovascular diseases, and neurodegenerative diseases.

Modulators of methyl modifying enzymes, compositions and uses thereof

Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein.

ACETYLENIC MICROBIOCIDES

Compounds of formula (I), wherein the other substituents HetAr, A', R1, R2, R3, R4, R5, R6, R7, R8 and R9 are as defined in claim 1, and their use in compositions and methods for the control and/or prevention of microbial infection, particularly fungal infection, in plants and to processes for the preparation of these compounds.

CONDENSED TRICLYCLIC COMPOUNDS AS INHIBITORS OF HIV REPLICATION

Compounds of formula (I) and pharmaceutical compositions thereof: wherein A1 A2 and A3 are each independently selected from the group consisting of N and CR3, wherein R1 is an optionally substituted heterocyclyl or an optionally substituted -(C1-6)alkyl-heterocyclyl, R2 is an optionally substituted aryl or an optionally subsisted heteroaryl, R4 is an optionally substituted aryl, an optionally substituted heterocyclyl or an optionally substituted heteroaryl, useful as an inbitor of HIV replication.

NOVEL BENZOXAZINE OXAZOLIDINONE COMPOUNDS, PREPARATION METHODS AND USES THEREOF

Novel benzoxazine oxazolidinone compounds, preparation methods and uses thereof are disclosed, which belong to the field of pharmacy. More specifically, novel benzoxazine oxazolidinone compounds represented by the following formula (I), preparation method

MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF

Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein

Antibacterial Compounds

The present invention provides a compound of the following formula, salts, racemates, diastereomers, enantiomers, esters, carbamates, phosphates, sulfates, deuterated forms and prodrugs thereof. Also provided is the use of these compounds as antibacterials, compositions comprising them and processes for their manufacture.

PHENICOL ANTIBACTERIALS

The present invention provides novel phenicol derivatives, their use for the treatment of infections in mammals, pharmaceutical composition containing these novel compounds, and methods for the preparation of these compounds.