162709-22-0

Basic information

• Product Name: tert-butyl 4-forMyl-2-Methoxypyridin-3-ylcarbaMate
• Synonyms: tert-butyl 4-forMyl-2-Methoxypyridin-3-ylcarbaMate
• CAS NO: 162709-22-0
• Molecular Formula: C12H16N2O4
• Molecular Weight: 252.26644
• Mol File: 162709-22-0.mol

Chemical Properties

• Boiling Point: 334.1±42.0 °C(Predicted)
• Appearance: /
• Density: 1.216±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 11.79±0.70(Predicted)
• CAS DataBase Reference: tert-butyl 4-forMyl-2-Methoxypyridin-3-ylcarbaMate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4-forMyl-2-Methoxypyridin-3-ylcarbaMate(162709-22-0)
• EPA Substance Registry System: tert-butyl 4-forMyl-2-Methoxypyridin-3-ylcarbaMate(162709-22-0)

Safety Data

• Hazardous Substances Data: 162709-22-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Tert-butyl 4-formyl-2-methoxypyridin-3-ylcarbamate is used as an enzyme inhibitor or substrate for its potential biological activity, making it a valuable compound in the development of pharmaceuticals.
Used in Chemical Research and Synthesis:
tert-butyl 4-forMyl-2-Methoxypyridin-3-ylcarbaMate is also utilized in chemical research and synthesis processes, where its unique structure and functional groups contribute to the creation of new chemical entities and the advancement of scientific understanding.

Upstream product

• 2591-86-8 N-Formylpiperidine 
• 161117-83-5 3-(N-tert-butoxycarbonylamino)-2-methoxypyridine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 24608-52-4 tert-butyl chloroformate 
• 4394-85-8 4-morpholinecarboxaldehyde 
• 20265-38-7 3-amino-2-methoxypyridine 
• 68-12-2 N,N-dimethyl-formamide 

Relevant articles and documents

Synthesis method of 8-chloro-1, 7-naphthyridine-3-formaldehyde

The invention discloses a synthesis method of 8-chloro-1, 7-naphthyridine-3-formaldehyde, which comprises the following synthesis steps: 1) taking a compound I 2-methoxy-3-aminopyridine as an initialraw material, protecting amino to obtain a compound II; 2) reacting the compound II with an hydroformylation reagent under an alkaline condition to obtain a compound III; 3) deprotecting the compoundIII under an acidic condition to obtain a compound IV or a salt of the compound IV; 4) performing cyclization reaction on the compound IV and an acrylate compound under the action of a Lewis acid to prepare a compound V; 5) carrying out chlorination reaction on the compound V and a chlorination reagent to prepare a compound VI; and 6) dissolving the compound VI 8-chloro-1, 7-naphthyridine-3-formate as a raw material in a solvent, and reducing under the action of a reducing reagent to directly obtain 8-chloro-1, 7-naphthyridine-3-formaldehyde, namely a compound VII. The preparation method disclosed by the invention has the characteristics of suitability for industrial production, relatively low cost and simple operation.

8-SUBSTITUTED QUINOLINES AND RELATED ANALOGS AS SIRTUIN MODULATORS

Provided herein are 8-substituted quinolines and related analogues as sirtuin-modulating compounds of Structural Formula (I) and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.