162711-45-7

Basic information

• Product Name: 3-(benzyloxy)benzene-1-sulfonyl chloride
• Synonyms: 3-(benzyloxy)benzene-1-sulfonyl chloride;3-(Benzyloxy)benzenesulfonyl chloride
• CAS NO: 162711-45-7
• Molecular Formula: C₁₃H₁₁ClO₃S
• Molecular Weight: 282.74264
• Mol File: 162711-45-7.mol

Chemical Properties

• Boiling Point: 417.9±28.0 °C(Predicted)
• Appearance: /
• Density: 1.341±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 3-(benzyloxy)benzene-1-sulfonyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(benzyloxy)benzene-1-sulfonyl chloride(162711-45-7)
• EPA Substance Registry System: 3-(benzyloxy)benzene-1-sulfonyl chloride(162711-45-7)

Safety Data

• Hazardous Substances Data: 162711-45-7(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
3-(Benzyloxy)benzene-1-sulfonyl chloride is used as a reagent in organic synthesis for the preparation of sulfonamides and sulfonate esters. Its sulfonyl chloride group allows for the formation of various chemical bonds, making it a valuable intermediate in the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-(Benzyloxy)benzene-1-sulfonyl chloride is used as a key building block for the synthesis of various drugs. Its ability to introduce the sulfonyl chloride functionality into organic compounds enables the development of new pharmaceutical agents with improved therapeutic properties.
Used in Agrochemical Industry:
3-(Benzyloxy)benzene-1-sulfonyl chloride is utilized in the production of agrochemicals, such as pesticides and herbicides. Its sulfonyl chloride group can be used to create active ingredients that effectively control pests and weeds, contributing to increased crop yields and protection of agricultural resources.
Used in Dye Industry:
In the dye industry, 3-(Benzyloxy)benzene-1-sulfonyl chloride is employed as a starting material for the synthesis of various dyes. Its unique chemical structure allows for the creation of dyes with specific color properties and improved stability, making it an essential component in the development of new dye formulations.

Upstream product

• 53087-13-1 3-(benzyloxy)phenyl bromide 
• 591-20-8 3-Bromophenol 
• 100-39-0 benzyl bromide 
• 121-47-1 3-aminobenzenesulfonic acid 

Downstream Products

• 261901-57-9 SB 269970 A 
• 431878-96-5 3-(benzyloxy)benzenethiol 
• 403825-36-5 (R)-1-(3-Benzyloxyphenylsulfonyl)-3-(tert-butoxycarbonylamino)-pyrrolidine 
• 261901-57-9 (R)-3-(2-(2-(4-methyl-piperidin-1-yl)ethyl)-pyrrolidine-1-sulfonyl)-phenol hydrochloride 
• 201038-72-4 (R)-1-(2-(1-(3-benzyloxy-benzenesuylfonyl)-pyrrolidin-2-yl)-ethyl)-4-methyl piperidine 

Relevant articles and documents

A NOVEL PROCESS FOR THE PREPARATION OF 3-(BENZYLOXY)- BENZENETHIOL, A KEY INTERMEDIATE FOR THE PREPARATION OF PHARMACEUTICAL DRUGS.

Disclosed herein is an efficient and economical process for the preparation of 3-Benzyloxybenzenethiol of formula-I which is a key intermediate for the preparation of pharmaceutical drugs. R'' is hydrogen, halogen, trihalomethyl, lower alkoxy having 1-4 c

INDAZOLE ANALOGUE

[Objective] To provide a drug that selectively stimulates the β3-adrenergic receptors, particularly a drug capable of preferentially stimulating the β3-adrenergic receptors over the α1-adrenergic receptors. This drug can be used in the treatment and prevention of diabetes, obesity, hyperlipidemia, depression, cholelithiasis, diseases caused by biliary hyperkinesia, diseases caused by hyperfunction of the gastrointestinal tract, interstitial cystitis, overactive bladder or urinary incontinence, diseases associated with decreased lacrimation, and the like. [Solution] Indazole analogs represented by the general formula (I) or a salt thereof. Drugs that contains these indazole analogs or a salt thereof as the active ingredient.

Efficient Arndt-Eistert synthesis of selective 5-HT7 receptor antagonist SB-269970

This contribution describes a novel Arndt-Eistert approach for the efficient synthesis of the potent and selective 5-HT7-antagonist, (R)-3-(2-(2-(4-methylpiperidin-1-yl)-ethyl)pyrrolidine-1-sulfonyl)phenol (SB-269970), from D-proline. The synthesis was ca

Inhibitors of prenyl-protein transferase

The present invention is directed to macrocyclic compounds which inhibit prenyl-protein transferase (FTase) and the prenylation of the oncogene protein Ras. The invention is further directed to chemothera-peutic compositions containing the compounds of this invention and methods for inhibiting prenyl-protein transferase and the prenylation of the oncogene protein Ras.