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162739-94-8

4-Oxazolemethanamine,N-methyl-2-(1-methylethyl)-(9CI) is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 162739-94-8 Structure

  • Basic information

    1. Product Name: 4-Oxazolemethanamine,N-methyl-2-(1-methylethyl)-(9CI)
    2. Synonyms: 4-Oxazolemethanamine,N-methyl-2-(1-methylethyl)-(9CI)
    3. CAS NO:162739-94-8
    4. Molecular Formula: C8H14N2O
    5. Molecular Weight: 154.20956
    6. EINECS: N/A
    7. Product Categories: ISOPROPYL
    8. Mol File: 162739-94-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-Oxazolemethanamine,N-methyl-2-(1-methylethyl)-(9CI)(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-Oxazolemethanamine,N-methyl-2-(1-methylethyl)-(9CI)(162739-94-8)
    11. EPA Substance Registry System: 4-Oxazolemethanamine,N-methyl-2-(1-methylethyl)-(9CI)(162739-94-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 162739-94-8(Hazardous Substances Data)

162739-94-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 162739-94-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,2,7,3 and 9 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 162739-94:
(8*1)+(7*6)+(6*2)+(5*7)+(4*3)+(3*9)+(2*9)+(1*4)=158
158 % 10 = 8
So 162739-94-8 is a valid CAS Registry Number.

162739-94-8Downstream Products

162739-94-8Relevant articles and documents

Discovery of ritonavir, a potent inhibitor of HIV protease with high oral bioavailability and clinical efficacy

Kempf, Dale J.,Sham, Hing L.,Marsh, Kennan C.,Flentge, Charles A.,Betebenner, David,Green, Brian E.,McDonald, Edith,Vasavanonda, Sudthida,Saldivar, Ayda,Wideburg, Norman E.,Kati, Warren M.,Ruiz, Lisa,Zhao, Chen,Fino, Lynnmarie,Patterson, Jean,Molla, Akhteruzzaman,Plattner, Jacob J.,Norbeck, Daniel W.

, p. 602 - 617 (2007/10/03)

The structure-activity studies leading to the potent and clinically efficacious HIV protease inhibitor ritonavir are described. Beginning with the moderately potent and orally bioavailable inhibitor A-80987, systematic investigation of peripheral (P3 and P2') heterocyclic groups designed to decrease the rate of hepatic metabolism provided analogues with improved pharmacokinetic properties after oral dosing in rats. Replacement of pyridyl groups with thiazoles provided increased chemical stability toward oxidation while maintaining sufficient aqueous solubility for oral absorption. Optimization of hydrophobic interactions with the HIV protease active site produced ritonavir, with excellent in vitro potency (EC50 = 0.02 μM) and high and sustained plasma concentrations after oral administration in four species. Details of the discovery and preclinical development of ritonavir are described.

RETROVIRAL PROTEASE INHIBITING COMPOUNDS

-

, (2008/06/13)

A retroviral protease inhibiting compound of the formula: STR1 is disclosed wherein R 1, R 2, R 5, R 6, Y m and Y' n are herein defined.

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