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(2-Bromo-4-methoxy-phenyl)methanol is an organic chemical compound characterized by the presence of a bromine atom, a methoxy group, and a hydroxyl group attached to a benzene ring. It is recognized for its role as a versatile building block in the synthesis of pharmaceuticals and agrochemicals, with the bromine atom enhancing its utility in the preparation of specialty chemicals. Its structural properties have also led to investigations into its potential as an antimicrobial agent, making it a compound of interest in organic synthesis and chemical research.

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  • 163190-79-2 Structure
  • Basic information

    1. Product Name: (2-Bromo-4-methoxy-phenyl)methanol
    2. Synonyms: (2-Bromo-4-methoxy-phenyl)methanol;2-Bromo-4-methoxybenzenemethanol
    3. CAS NO:163190-79-2
    4. Molecular Formula: C8H9BrO2
    5. Molecular Weight: 217.05986
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 163190-79-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 299.7±25.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.513±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 14.01±0.10(Predicted)
    10. CAS DataBase Reference: (2-Bromo-4-methoxy-phenyl)methanol(CAS DataBase Reference)
    11. NIST Chemistry Reference: (2-Bromo-4-methoxy-phenyl)methanol(163190-79-2)
    12. EPA Substance Registry System: (2-Bromo-4-methoxy-phenyl)methanol(163190-79-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 163190-79-2(Hazardous Substances Data)

163190-79-2 Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
(2-Bromo-4-methoxy-phenyl)methanol is used as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals, leveraging its unique structural features to contribute to the development of new and effective compounds for medical and agricultural applications.
Used in Specialty Chemicals Preparation:
As a building block, (2-Bromo-4-methoxy-phenyl)methanol is utilized in the preparation of specialty chemicals, where the bromine atom plays a crucial role in enhancing the compound's reactivity and properties for specific applications.
Used as a Reagent in Organic Chemistry Reactions:
(2-Bromo-4-methoxy-phenyl)methanol serves as a reagent in a range of organic chemistry reactions, facilitating the synthesis of complex organic molecules and contributing to the advancement of chemical research.
Used in Antimicrobial Research:
Due to its structural properties, (2-Bromo-4-methoxy-phenyl)methanol has been investigated for its potential use as an antimicrobial agent, with ongoing research aimed at understanding and harnessing its capabilities to combat microbial infections.

Check Digit Verification of cas no

The CAS Registry Mumber 163190-79-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,3,1,9 and 0 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 163190-79:
(8*1)+(7*6)+(6*3)+(5*1)+(4*9)+(3*0)+(2*7)+(1*9)=132
132 % 10 = 2
So 163190-79-2 is a valid CAS Registry Number.

163190-79-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (2-bromo-4-methoxyphenyl)methanol

1.2 Other means of identification

Product number -
Other names Benzenemethanol,2-bromo-4-methoxy

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:163190-79-2 SDS

163190-79-2Relevant articles and documents

Copper-Catalyzed Aerobic Oxidative Cyclization Cascade to Construct Bridged Skeletons: Total Synthesis of (?)-Suaveoline

Tan, Qiuyuan,Yang, Zhao,Jiang, Dan,Cheng, Yuegang,Yang, Jiao,Xi, Song,Zhang, Min

supporting information, p. 6420 - 6424 (2019/04/13)

Based on the discovery of copper-catalyzed cyclopropanol ring-opening addition to iminium ions, an unprecedented catalytic aerobic C?H oxidation/cyclopropanol cyclization cascade using CuCl2 as the multifunctional catalyst and air as the oxidant was developed to construct the azabicyclo[3.3.1]nonane skeleton, which is widespread in natural products and medicines. Using this method, concise asymmetric total synthesis of the indole alkaloid (?)-suaveoline was achieved. This study not only provides an efficient, low-cost, and environmentally benign method for constructing such bridged frameworks, but also enriches the realm of cyclopropanol chemistry and C?H functionalization.

Stereoselective Convergent Synthesis of Tetrahydro-5 H-benzo[c]fluorene via Nine-Membered Ring-Closing Metathesis and Transannular Acid-Mediated Cyclization/Nucleophilic Addition

Lekky, Anek,Ruengsatra, Tanachote,Ruchirawat, Somsak,Ploypradith, Poonsakdi

, p. 5277 - 5291 (2019/05/10)

The diene methyl ethers or acetates, constructed from the Li-Br exchange/addition reactions of 2-vinylbenzaldehydes and 2-(but-3-en-1-yl)bromoarenes followed by etherification or acetylation of the corresponding alcohols, smoothly underwent the ring-closi

Cyclic sulfamidates as versatile lactam precursors. An evaluation of synthetic strategies towards (-)-aphanorphine

Bower, John F.,Szeto, Peter,Gallagher, Timothy

, p. 143 - 150 (2008/03/28)

A full account of studies which led to the efficient asymmetric synthesis of (-)-aphanorphine 1 is reported. Two routes to the key cyclic sulfamidate intermediate 5 are described, the first was based on a chiral auxiliary approach and the second utilised

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