54788-18-0

Basic information

• Product Name: 2-bromo-1-(bromomethyl)-4-methoxybenzene
• Synonyms: 2-bromo-1-(bromomethyl)-4-methoxybenzene
• CAS NO: 54788-18-0
• Molecular Formula: C₈H₈Br₂O
• Molecular Weight: 279.95652
• Mol File: 54788-18-0.mol
• Article Data: 10

Chemical Properties

• Melting Point: 54-56 °C(Solv: ligroine (8032-32-4))
• Boiling Point: 292.0±25.0 °C(Predicted)
• Appearance: /
• Density: 1.759±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-bromo-1-(bromomethyl)-4-methoxybenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-1-(bromomethyl)-4-methoxybenzene(54788-18-0)
• EPA Substance Registry System: 2-bromo-1-(bromomethyl)-4-methoxybenzene(54788-18-0)

Safety Data

• Hazardous Substances Data: 54788-18-0(Hazardous Substances Data)

Upstream product

• 36942-56-0 3-bromo-4-methylanisole 
• 163190-79-2 (2-bromo-4-methoxyphenyl)methanol 
• 2398-37-0 3-methoxyphenyl bromide 
• 66916-97-0 2-bromo-4-methoxybenzyl chloride 
• 60710-39-6 3-bromo-p-cresol 
• 7745-91-7 3-bromo-4-methylaniline 
• 43192-31-0 2-bromo-4-methoxybenzaldehyde 
• 50-00-0 formaldehyd 

Downstream Products

• 848142-47-2 N-(2-bromo-4-methoxybenzyl)-N-(4-methoxyphenyl)hydrazine 
• 155855-29-1 2-(4-Methoxy-2-bromobenzyl)-3,3-dimethyl-1-methylenecyclohexane 
• 1356395-35-1 N-(tert-butyldiphenylsilyl) (2-bromo-4-methoxyphenyl)ethyl methyl sulfoximine 
• 1356395-36-2 (2-bromo-4-methoxyphenyl)ethyl methyl sulfoximine 
• 66916-98-1 2-(2-bromo-4-methoxyphenyl)acetonitrile 

Relevant articles and documents

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Synthesis of 2-naphthols via carbonylative stille coupling reaction of 2-bromobenzyl bromides with tributylallylstannane followed by the heck reaction

A method for the synthesis of 2-naphthols 4 is described. The carbonylative Stille coupling reactions of 2-bromobenzyl bromides with tributylallylstannane to produce 2-bromobenzyl β,γ-unsaturated ketones 2 in satisfactory to excellent yields has been achieved. The isomerization of 2-bromobenzyl β,γ-unsaturated ketones 2 can readily occur under basic conditions to generate 2-bromobenzyl α,β-unsaturated ketones 3. The 2-bromobenzyl α,β-unsaturated ketones 3 can be transformed into 2-naphthols 4 via intramolecular Heck reaction in satisfactory to good yields (Figure presented).