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2-(4-aminophenyl)-6-aminobenzoxazole, a heterocyclic aromatic compound with the molecular formula C13H11N3O, features both an aminophenyl and an aminobenzoxazole group. This chemical compound holds potential in various fields due to its antimicrobial and anticancer properties, and its utility as a building block in the synthesis of organic compounds.

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  • 16363-53-4 Structure
  • Basic information

    1. Product Name: 2-(4-AMINOPHENYL)-6-AMINOBENZOXAZOLE
    2. Synonyms: 2-(4-AMINOPHENYL)-6-AMINOBENZOXAZOLE;6-Amino-2-(4-aminophenyl)benzoxazole;6-Amino-2-(p-aminophenyl)benzoxazole;2-(4-AMinophenyl)benzo[d]oxazol-6-aMine
    3. CAS NO:16363-53-4
    4. Molecular Formula: C13H11N3O
    5. Molecular Weight: 225.24594
    6. EINECS: N/A
    7. Product Categories: electronic;Chemical Amines;Amines;Aromatics;Heterocycles
    8. Mol File: 16363-53-4.mol
  • Chemical Properties

    1. Melting Point: 194-195 °C
    2. Boiling Point: 435.2 °C at 760 mmHg
    3. Flash Point: 217 °C
    4. Appearance: /
    5. Density: 1.329 g/cm3
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: DMSO (Slightly), Methanol (Slightly)
    9. PKA: 3.25±0.10(Predicted)
    10. CAS DataBase Reference: 2-(4-AMINOPHENYL)-6-AMINOBENZOXAZOLE(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-(4-AMINOPHENYL)-6-AMINOBENZOXAZOLE(16363-53-4)
    12. EPA Substance Registry System: 2-(4-AMINOPHENYL)-6-AMINOBENZOXAZOLE(16363-53-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 16363-53-4(Hazardous Substances Data)

16363-53-4 Usage

Uses

Used in Pharmaceutical Industry:
2-(4-aminophenyl)-6-aminobenzoxazole is used as an antimicrobial agent for its ability to combat various microorganisms, which can be crucial in the development of new antibiotics to address the growing issue of antibiotic resistance.
2-(4-aminophenyl)-6-aminobenzoxazole is also used as an anticancer agent due to its potential to inhibit the growth of cancer cells, making it a candidate for further research and development in oncology.
Used in Chemical Synthesis:
In the field of organic chemistry, 2-(4-aminophenyl)-6-aminobenzoxazole serves as a valuable building block for the synthesis of a variety of organic compounds, contributing to the creation of new molecules with diverse applications.
Used in Industrial Applications:
2-(4-aminophenyl)-6-aminobenzoxazole may have potential in the development of new materials and chemical processes within the industry, although further research is necessary to fully explore and understand its capabilities and applications in this area.

Check Digit Verification of cas no

The CAS Registry Mumber 16363-53-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,3,6 and 3 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 16363-53:
(7*1)+(6*6)+(5*3)+(4*6)+(3*3)+(2*5)+(1*3)=104
104 % 10 = 4
So 16363-53-4 is a valid CAS Registry Number.

16363-53-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-Amino-2-(4-aminophenyl)benzoxazole

1.2 Other means of identification

Product number -
Other names 2-(4-aminophenyl)-1,3-benzoxazol-6-amine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:16363-53-4 SDS

16363-53-4Downstream Products

16363-53-4Relevant articles and documents

METHOD FOR MANUFACTURING BENZOXAZOLE COMPOUNDS

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Paragraph 0028; 0033-0034, (2017/04/28)

A method for manufacturing benzoxazole compounds is provided and has steps of: processing a reaction between o-aminophenol or a derivative thereof and an acyl chloride compound, so as to obtain a first product; and adding the first product into a solution of polyphosphoric acid to carry out a cyclization, so as to form a benzoxazole compound.

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