1644629-23-1 Usage
Molecular structure
1-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine has a complex molecular structure consisting of a pyrrolopyridine core and a boron-containing dioxaborolane group.
Pyrrolopyridine core
The molecule features a pyrrolopyridine core, which is a five-membered ring containing two nitrogen atoms, contributing to its unique chemical properties.
Dioxaborolane group
A boron-containing dioxaborolane group is attached to the pyrrolopyridine core, which consists of a five-membered ring with two oxygen atoms and a boron atom.
Boron atom reactivity
The boron atom in the dioxaborolane group can be used as a site for further chemical reactions, making the compound a versatile building block for synthetic chemistry.
Methyl group contributions
Methyl groups are attached to both the boron and the pyrrolopyridine ring, contributing to the molecule's stability and hydrophobicity.
Potential applications
Due to its unique structure and reactivity, 1-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine may have potential applications in various fields, such as medicinal chemistry, materials science, and organic synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 1644629-23-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,4,4,6,2 and 9 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1644629-23:
(9*1)+(8*6)+(7*4)+(6*4)+(5*6)+(4*2)+(3*9)+(2*2)+(1*3)=181
181 % 10 = 1
So 1644629-23-1 is a valid CAS Registry Number.
1644629-23-1Relevant articles and documents
HPK1 ANTAGONISTS AND USES THEREOF
-
, (2021/03/19)
The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of HPK1, and the treatment of HPK1-mediated disorders.
Rh-catalyzed decarbonylative coupling with alkynes via C-C activation of isatins
Zeng, Rong,Dong, Guangbin
supporting information, p. 1408 - 1411 (2015/02/19)
Herein we report a [5 + 2 - 1] transformation though catalytic decarbonylative coupling between isatins and alkynes, which provides a unique way to synthesize 2-quinolinone derivatives. A broad range of alkynes can be coupled efficiently with high regioselectivity. This reaction is proposed to go through C-C activation of isatins, followed by decarbonylation and alkyne insertion. Directing group (DG) plays a critical role in this transformation. Assisted by the DG, the C-C cleavage of isatins occurs at room temperature.
