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165065-02-1

2'-O-(tert-Butyldimethylsilyl)-6,7-dehydropaclitaxel is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 165065-02-1 Structure

  • Basic information

    1. Product Name: 2'-O-(tert-Butyldimethylsilyl)-6,7-dehydropaclitaxel
    2. Synonyms: 2'-O-(tert-Butyldimethylsilyl)-6,7-dehydropaclitaxel
    3. CAS NO:165065-02-1
    4. Molecular Formula: C53H63NO13Si
    5. Molecular Weight: 950.161
    6. EINECS: N/A
    7. Product Categories: Chiral Reageats;Intermediates & Fine Chemicals;Pharmaceuticals;Chiral Reageats, Pharmaceuticals, Intermediates & Fine Chemicals
    8. Mol File: 165065-02-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: Chloroform, Dichloromethane, Ethyl Acetate, Methanol
    9. CAS DataBase Reference: 2'-O-(tert-Butyldimethylsilyl)-6,7-dehydropaclitaxel(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2'-O-(tert-Butyldimethylsilyl)-6,7-dehydropaclitaxel(165065-02-1)
    11. EPA Substance Registry System: 2'-O-(tert-Butyldimethylsilyl)-6,7-dehydropaclitaxel(165065-02-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 165065-02-1(Hazardous Substances Data)

165065-02-1 Usage

Chemical Properties

White Solid

Check Digit Verification of cas no

The CAS Registry Mumber 165065-02-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,5,0,6 and 5 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 165065-02:
(8*1)+(7*6)+(6*5)+(5*0)+(4*6)+(3*5)+(2*0)+(1*2)=121
121 % 10 = 1
So 165065-02-1 is a valid CAS Registry Number.

165065-02-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2'-O-(tert-butyldimethylsilyl)-6,7-dehydropaclitaxel

1.2 Other means of identification

Product number -
Other names 2'-NITROCINNAMALDEHYDE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:165065-02-1 SDS

165065-02-1Relevant articles and documents

Paclitaxel analogs modified in ring C: Synthesis and biological evaluation

Liang, Xian,Kingston, David G.I.,Long, Byron H.,Fairchild, Craig A.,Johnston, Kathy A.

, p. 3441 - 3456 (2007/10/03)

Lead tetracetate oxidation of 6α-hydroxy-7-epi-paclitaxel lends to C-nor-paclitaxel and C-seco-paclitaxel derivatives. Tetrpropylammonium perruthnate (TPAP) oxidation of a 6α-hydroxy-7-epi-paclitaxel derivative leads to a 6-formyl-C-nor-paclitaxel derivative. Reaction of a 6α-O-trifluoromethanesulfonyl-7-epi-paclitaxel derivative with DMAP yields a 20-O-acetyl-4-deacetyl-5,6-dehydro-6-formyl-C-nor-paclitaxel derivative. C-nor-paclitaxel analogs are less active than paclitaxel.

Synthesis of novel taxol analogs and evaluation of their biological activities

Wender, Paul A.,Lee, Daesung,Lal, Tapan K.,Horwitz, Susan B.,Rao, Srinivasa

, p. 1941 - 1944 (2007/10/03)

Two new taxol analogs 6 and 10 have been prepared from baccatin III (1) and taxol (7a), respectively. Like taxol, both compounds were found to promote microtubule formation and stabilization, although they were less active than taxol. Both 6 and 10 exhibi

Synthesis and Biological Evaluation of Paclitaxel Analogs Modified in Ring C

Liang, Xian,Kingston, David G. I.,Lin, Chii M.,Hamel, Ernest

, p. 2901 - 2904 (2007/10/02)

Both 7-deoxy-7α-azidopaclitaxel (6) and 7-deoxy-Δ6,7-paclitaxel (4) can be prepared from paclitaxel-7-O-triflate (2b).Oxidation of 7-deoxy-Δ6,7-paclitaxel with dioxirane yields the epoxide 7, while oxidation with osmium tetroxide yie

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