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2'-O-(t-butyldimethylsilyl)-7β-O-trifluoromethanesulfonyl-paclitaxel is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

165065-01-0

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165065-01-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 165065-01-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,5,0,6 and 5 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 165065-01:
(8*1)+(7*6)+(6*5)+(5*0)+(4*6)+(3*5)+(2*0)+(1*1)=120
120 % 10 = 0
So 165065-01-0 is a valid CAS Registry Number.

165065-01-0Relevant articles and documents

Paclitaxel analogs modified in ring C: Synthesis and biological evaluation

Liang, Xian,Kingston, David G.I.,Long, Byron H.,Fairchild, Craig A.,Johnston, Kathy A.

, p. 3441 - 3456 (1997)

Lead tetracetate oxidation of 6α-hydroxy-7-epi-paclitaxel lends to C-nor-paclitaxel and C-seco-paclitaxel derivatives. Tetrpropylammonium perruthnate (TPAP) oxidation of a 6α-hydroxy-7-epi-paclitaxel derivative leads to a 6-formyl-C-nor-paclitaxel derivative. Reaction of a 6α-O-trifluoromethanesulfonyl-7-epi-paclitaxel derivative with DMAP yields a 20-O-acetyl-4-deacetyl-5,6-dehydro-6-formyl-C-nor-paclitaxel derivative. C-nor-paclitaxel analogs are less active than paclitaxel.

Synthesis and Biological Evaluation of Paclitaxel Analogs Modified in Ring C

Liang, Xian,Kingston, David G. I.,Lin, Chii M.,Hamel, Ernest

, p. 2901 - 2904 (2007/10/02)

Both 7-deoxy-7α-azidopaclitaxel (6) and 7-deoxy-Δ6,7-paclitaxel (4) can be prepared from paclitaxel-7-O-triflate (2b).Oxidation of 7-deoxy-Δ6,7-paclitaxel with dioxirane yields the epoxide 7, while oxidation with osmium tetroxide yie

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