165671-05-6

Basic information

• Product Name: 4,5-Difluoro-2-nitrobenzonitrile
• Synonyms: 3,4-Difluoro-6-nitrobenzonitrile;4,5-Difluoro-2-nitrobenzonitrile
• CAS NO: 165671-05-6
• Molecular Formula: C₇H₂F₂N₂O₂
• Molecular Weight: 184.1
• Mol File: 165671-05-6.mol

Chemical Properties

• Boiling Point: 312.9°C at 760 mmHg
• Flash Point: 143°C
• Appearance: /
• Density: 1.51g/cm³
• Vapor Pressure: 0.000514mmHg at 25°C
• Refractive Index: 1.529
• CAS DataBase Reference: 4,5-Difluoro-2-nitrobenzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-Difluoro-2-nitrobenzonitrile(165671-05-6)
• EPA Substance Registry System: 4,5-Difluoro-2-nitrobenzonitrile(165671-05-6)

Safety Data

• Hazardous Substances Data: 165671-05-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
4,5-Difluoro-2-nitrobenzonitrile is utilized as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. Its reactivity allows for the preparation of a wide range of organic compounds, making it a crucial component in these industries.
Used in Dye and Pigment Production:
4,5-Difluoro-2-nitrobenzonitrile is also used as a reagent in the production of various dyes and pigments. Its unique properties contribute to the development of colorants with specific characteristics for different applications.
Used in Polymer and Specialty Chemical Manufacturing:
4,5-Difluoro-2-nitrobenzonitrile finds application in the manufacturing of polymers and other specialty chemicals. Its role in these processes is significant, as it helps in creating materials with tailored properties for specific uses.

InChI:InChI=1/C7H2F2N2O2/c8-5-1-4(3-10)7(11(12)13)2-6(5)9/h1-2H

Upstream product

• 64248-62-0 3,4-Difluorobenzonitrile 
• 20372-63-8 4,5-difluoro-2-nitrobenzoic acid 

Downstream Products

• 1217301-65-9 ethyl 2-cyano-4,5-difluorophenylcarbamate 
• 219823-49-1 2-amino-4,5-difluorobenzonitrile 

Relevant articles and documents

HETEROCYCLIC INHIBITORS OF HISTAMINE RECEPTORS FOR THE TREATMENT OF DISEASE

The present invention relates to compounds and methods which may be useful as inhibitors of H1R and/or H4R for the treatment or prevention of inflammatory, autoimmune, allergic, and ocular diseases.

Method for the production of N-(5-amino-2-cyano-4-fluoro-phenyl)-sulphonamides and new intermediate products

The invention relates to a process for preparing N-(5-amino-2-cyano-4-fluoro-phenyl)-sulphonamides in which, in a first step, 2-amino-4,5-difluoro-benzonitrile is reacted with sulphonyl halides in the presence of an acid acceptor and in the presence of a