- Selective sodium channel regulator as well as preparation and application thereof
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The invention provides a compound serving as a selective sodium channel regulator and a synthesis and use method, and particularly provides a compound shown as a formula (I), a preparation method of the compound and application of the compound serving as the selective sodium channel regulator. The compounds exhibit excellent activity as a regulator of sodium channels.
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Paragraph 0088; 0090; 0106-0108
(2021/02/10)
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- Selective sodium channel regulator, preparation and application thereof
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The invention provides a compound as a selective sodium channel regulator, a synthesis method and a use method thereof, and particularly provides a compound as shown in a formula (I), a preparation method of the compound and application of the compound as the selective sodium channel regulator. The compounds exhibit excellent activity as sodium channel modulators.
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Paragraph 0083; 0085; 0092; 0093; 0094
(2021/07/01)
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- Selective sodium channel regulator as well as preparation and application thereof
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The invention provides a compound serving as a selective sodium channel regulator and a synthesis and use method, and particularly provides a compound shown as a formula (I), a preparation method of the compound and application of the compound serving as the selective sodium channel regulator. The compounds exhibit excellent activity as a regulator of sodium channels.
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Paragraph 0094-0095; 0102-0104
(2021/02/10)
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- ESTERS AND CARBAMATES AS MODULATORS OF SODIUM CHANNELS
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Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.
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Paragraph 00358; 00359
(2020/07/25)
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- CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS
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Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.
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Paragraph 00948
(2020/07/25)
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- CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS
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Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.
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Paragraph 00719; 00721; 00722
(2019/01/30)
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