166312-49-8

Basic information

• Product Name: 2-methoxy-4-(trifluoromethyloxy)phenol
• Synonyms: 2-methoxy-4-(trifluoromethyloxy)phenol;2-methoxy-4-(trifluoromethoxy)phenol;Phenol, 2-methoxy-4-(trifluoromethoxy)
• CAS NO: 166312-49-8
• Molecular Formula: C8H7F3O3
• Molecular Weight: 208.1345896
• Mol File: 166312-49-8.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 224.0±35.0 °C(Predicted)
• Appearance: /
• Density: 1.366±0.06 g/cm3(Predicted)
• PKA: 9.36±0.18(Predicted)
• CAS DataBase Reference: 2-methoxy-4-(trifluoromethyloxy)phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methoxy-4-(trifluoromethyloxy)phenol(166312-49-8)
• EPA Substance Registry System: 2-methoxy-4-(trifluoromethyloxy)phenol(166312-49-8)

Safety Data

• Hazardous Substances Data: 166312-49-8(Hazardous Substances Data)

Usage

General Description

2-methoxy-4-(trifluoromethyloxy)phenol, also known as methoxytrifluoromethylphenol, is a chemical compound with the molecular formula C8H7F3O2. It is a white to off-white solid that is soluble in organic solvents. 2-methoxy-4-(trifluoromethyloxy)phenol is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals, and as a reagent in organic chemistry. It has been studied for its potential use as an anti-inflammatory and analgesic agent. Additionally, it has been identified as a potential biomarker for certain medical conditions, and has also been investigated for its antimicrobial and antifungal properties. However, it is important to handle this compound with caution, as it is considered to be harmful if swallowed, inhaled, or in contact with skin, and can cause irritation to the eyes and respiratory system.

Upstream product

• 355836-10-1 2-methoxy-4-trifluoromethoxybenzeneboronic acid 
• 848360-85-0 1-bromo-2-methoxy-4-(trifluoromethoxy)benzene 
• 205371-26-2 2-bromo-5-(trifluoromethyloxy)phenol 

Relevant articles and documents

Selective sodium channel regulator as well as preparation and application thereof

The invention provides a compound serving as a selective sodium channel regulator and a synthesis and use method, and particularly provides a compound shown as a formula (I), a preparation method of the compound and application of the compound serving as the selective sodium channel regulator. The compounds exhibit excellent activity as a regulator of sodium channels.

Selective sodium channel regulator as well as preparation and application thereof

The invention provides a compound serving as a selective sodium channel regulator and a synthesis and use method, and particularly provides a compound shown as a formula (I), a preparation method of the compound and application of the compound serving as the selective sodium channel regulator. The compounds exhibit excellent activity as a regulator of sodium channels.

CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS

Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.