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2-methoxy-4-(trifluoromethyloxy)phenol, also known as methoxytrifluoromethylphenol, is a chemical compound characterized by the molecular formula C8H7F3O2. It is a white to off-white solid that exhibits solubility in organic solvents. 2-methoxy-4-(trifluoromethyloxy)phenol is recognized for its versatile applications in various fields, including pharmaceuticals, agrochemicals, and organic chemistry, where it serves as an intermediate and a reagent. Its potential as an anti-inflammatory and analgesic agent has been a subject of study, along with its identification as a biomarker for certain medical conditions. Furthermore, it has shown promise in antimicrobial and antifungal applications. However, due to its harmful nature upon ingestion, inhalation, or skin contact, and its potential to cause eye and respiratory irritation, careful handling is advised.

166312-49-8

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166312-49-8 Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
2-methoxy-4-(trifluoromethyloxy)phenol is utilized as an intermediate in the synthesis of various pharmaceuticals and agrochemicals, contributing to the development of new drugs and pesticides. Its unique chemical structure allows for the creation of a wide range of compounds with specific therapeutic or pesticidal properties.
Used in Organic Chemistry:
As a reagent in organic chemistry, 2-methoxy-4-(trifluoromethyloxy)phenol facilitates various chemical reactions, enabling the synthesis of complex organic molecules. Its presence can influence reaction pathways and outcomes, making it a valuable tool in the field of organic synthesis.
Used in Medical Research:
2-methoxy-4-(trifluoromethyloxy)phenol is studied for its potential as an anti-inflammatory and analgesic agent, indicating its use in the development of new treatments for pain and inflammation-related conditions. Its role as a potential biomarker for certain medical conditions also highlights its importance in diagnostic applications.
Used in Antimicrobial and Antifungal Applications:
2-methoxy-4-(trifluoromethyloxy)phenol has been investigated for its antimicrobial and antifungal properties, suggesting its use in the development of new antimicrobial agents to combat resistant strains of bacteria and fungi. This could be particularly relevant in the fields of medicine and agriculture, where resistance to existing treatments is a growing concern.

Check Digit Verification of cas no

The CAS Registry Mumber 166312-49-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,6,3,1 and 2 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 166312-49:
(8*1)+(7*6)+(6*6)+(5*3)+(4*1)+(3*2)+(2*4)+(1*9)=128
128 % 10 = 8
So 166312-49-8 is a valid CAS Registry Number.

166312-49-8Downstream Products

166312-49-8Relevant academic research and scientific papers

Selective sodium channel regulator as well as preparation and application thereof

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Paragraph 0088; 0090; 0106-0108, (2021/02/10)

The invention provides a compound serving as a selective sodium channel regulator and a synthesis and use method, and particularly provides a compound shown as a formula (I), a preparation method of the compound and application of the compound serving as the selective sodium channel regulator. The compounds exhibit excellent activity as a regulator of sodium channels.

Selective sodium channel regulator, preparation and application thereof

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Paragraph 0083; 0085; 0092; 0093; 0094, (2021/07/01)

The invention provides a compound as a selective sodium channel regulator, a synthesis method and a use method thereof, and particularly provides a compound as shown in a formula (I), a preparation method of the compound and application of the compound as the selective sodium channel regulator. The compounds exhibit excellent activity as sodium channel modulators.

Selective sodium channel regulator as well as preparation and application thereof

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Paragraph 0094-0095; 0102-0104, (2021/02/10)

The invention provides a compound serving as a selective sodium channel regulator and a synthesis and use method, and particularly provides a compound shown as a formula (I), a preparation method of the compound and application of the compound serving as the selective sodium channel regulator. The compounds exhibit excellent activity as a regulator of sodium channels.

ESTERS AND CARBAMATES AS MODULATORS OF SODIUM CHANNELS

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Paragraph 00358; 00359, (2020/07/25)

Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.

CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS

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Paragraph 00948, (2020/07/25)

Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.

CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS

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Paragraph 00719; 00721; 00722, (2019/01/30)

Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.

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