166530-78-5

Basic information

• Product Name: 5-BROMO-2-METHOXYBENZYLAMINE
• Synonyms: 5-BROMO-2-METHOXYBENZYLAMINE;(5-bromo-2-methoxyphenyl)methanamine;5-BROMO-2-METHOXYBENZYLAMIN;5-Bromo-2-methoxy-benzenemethanamine;(5-Bromo-2-methoxyphenyl)
• CAS NO: 166530-78-5
• Molecular Formula: C₈H₁₀BrNO
• Molecular Weight: 216.08
• Product Categories: Anilines, Aromatic Amines and Nitro Compounds
• Mol File: 166530-78-5.mol

Chemical Properties

• Boiling Point: 282.9 °C at 760 mmHg
• Flash Point: 124.9 °C
• Appearance: /
• Density: 1.444 g/cm³
• Vapor Pressure: 0.00326mmHg at 25°C
• Refractive Index: 1.569
• Storage Temp.: 2-8°C(protect from light)
• PKA: 8.86±0.10(Predicted)
• CAS DataBase Reference: 5-BROMO-2-METHOXYBENZYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-2-METHOXYBENZYLAMINE(166530-78-5)
• EPA Substance Registry System: 5-BROMO-2-METHOXYBENZYLAMINE(166530-78-5)

Safety Data

• Hazardous Substances Data: 166530-78-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research and Development:
5-Bromo-2-methoxybenzylamine is used as a building block for the synthesis of new pharmaceuticals due to its unique structure and properties. It aids in the development of innovative drugs and analogs, contributing to advancements in medicinal chemistry.
Used in Organic Synthesis:
As a versatile chemical compound, 5-Bromo-2-methoxybenzylamine is utilized in organic synthesis for creating a variety of derivatives, expanding the scope of chemical reactions and products.
Used in the Preparation of Biologically Active Compounds:
5-Bromo-2-methoxybenzylamine serves as a reagent in the preparation of biologically active compounds, which are essential for various applications in the life sciences and medicine.
Used in the Synthesis of Heterocyclic Compounds:
5-BROMO-2-METHOXYBENZYLAMINE is employed in the synthesis of heterocyclic compounds, which are important in various fields, including pharmaceuticals, agrochemicals, and materials science.
Used in the Production of Fine Chemicals and Agrochemicals:
5-Bromo-2-methoxybenzylamine has potential applications in the production of fine chemicals and agrochemicals, where its unique properties can be harnessed to create high-value products for diverse industries.

InChI:InChI=1/C8H10BrNO/c1-11-8-3-2-7(9)4-6(8)5-10/h2-4H,5,10H2,1H3

Upstream product

• 25016-01-7 5-bromo-2-methoxybenzaldehyde 
• 7017-52-9 4-bromo-2-(chloromethyl)-1-methoxybenzene 
• 80866-82-6 5-bromo-2-methoxy-benzyl alcohol 
• 144649-99-0 5-bromo-2-methoxybenzonitrile 

Downstream Products

• 1338254-39-9 N-(3-bromo-6-methoxy-benzyl)-2,2-diethoxy-acetamidine 
• 334015-82-6 t-Butyl N-(5-bromo-2-methoxybenzyl)carbamate 

Relevant articles and documents

COMPOUNDS USEFUL IN INHIBITING DIACYLGLYCEROL O-ACYLTRANSFERASE AND METHODS OF MAKING AND USING THE SAME

Described herein are compounds that may act as an inhibitor of diacylglycerol O- acyltransferase 2 (DGAT2) and/or that may be useful in the treatment of diseases and/or disorders associated with DGAT2. Compositions including such compounds are also described herein along with methods of preparation and use of such compounds and/or compositions.

First Contact: 7-Phenyl-2-Aminoquinolines, Potent and Selective Neuronal Nitric Oxide Synthase Inhibitors That Target an Isoform-Specific Aspartate

Inhibition of neuronal nitric oxide synthase (nNOS), an enzyme implicated in neurodegenerative disorders, is an attractive strategy for treating or preventing these diseases. We previously developed several classes of 2-aminoquinoline-based nNOS inhibitor

A Concise Enantioselective Synthesis of (+)-L-733,060 and (+)-T-2328 via Sequential Proline Catalysis

A new, sequential proline-catalyzed approach to the synthesis of (+)-L-733,060 and (+)-T-2328 in high optical purity (93% ee) is described starting from phenyl N-Boc imine. The strategy involves proline-catalyzed Mannich reaction of an arylimine with acet