16801-63-1

Basic information

• Product Name: 4-N-Cbz-cyclohexanone
• Synonyms: (4-OXOCYCLOHEXYL)CARBAMIC ACID BENZYL ESTER;4-N-CBZ-AMINO-CYCLOHEXANONE;4-N-CBZ-CYCLOHEXANONE;4-CARBOBENZOXY-AMINO-CYCLOHEXANONE;N-CBZ-4-AMINO-CYCLOHEXANONE ;(4-OXOCYCLOHEXYL)CARBAMIC ACID BENZYL ESTER, 95+%;4-(Benzyloxycarbonylamino)cyclohexanone, 97%;(4-Oxocyclohexyl)carbamic acid benzyl ester, 4-(Benzyloxycarbonylamino)cyclohexanone, Benzyl 4-oxocyclohexylcarbamate
• CAS NO: 16801-63-1
• Molecular Formula: C₁₄H₁₇NO₃
• Molecular Weight: 247.29
• Product Categories: pharmacetical;API intermediates
• Mol File: 16801-63-1.mol

Chemical Properties

• Melting Point: 86-87°C
• Boiling Point: 427.3 °C at 760 mmHg
• Flash Point: 212.2 °C
• Appearance: /
• Density: 1.17 g/cm³
• Vapor Pressure: 1.66E-07mmHg at 25°C
• Refractive Index: 1.55
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 11.98±0.20(Predicted)
• CAS DataBase Reference: 4-N-Cbz-cyclohexanone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-N-Cbz-cyclohexanone(16801-63-1)
• EPA Substance Registry System: 4-N-Cbz-cyclohexanone(16801-63-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 16801-63-1(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
4-N-Cbz-cyclohexanone is used as a reagent for the synthesis of amine compounds, where it provides protection to the amine functional group, enabling selective reactions to occur.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 4-N-Cbz-cyclohexanone is utilized in the synthesis of specific drugs. Its stability and ease of use in synthetic processes make it a valuable tool for chemists and researchers involved in drug development.

InChI:InChI=1/C14H17NO3/c16-13-8-6-12(7-9-13)15-14(17)18-10-11-4-2-1-3-5-11/h1-5,12H,6-10H2,(H,15,17)

Upstream product

• 27489-63-0 (trans)-(4-hydroxy-cyclohexyl)-carbamic acid benzyl ester 
• 6850-65-3 p-hydroxycyclohexylamine 
• 501-53-1 benzyl chloroformate 
• 27489-63-0 trans-4-<(benzyloxycarbonyl)amino>cyclohexanol 
• 7107-58-6 benzyl N-cyclohexylcarbamate 

Downstream Products

• 121936-54-7 phenylmethyl <4-hydroxyimino)cyclohexyl>carbamate 
• 918792-90-2 benzyl (6-(trifluoromethoxy)-2,3,4,9-tetrahydro-1H-carbazol-3-yl)carbamate 
• 918793-02-9 (±)-benzyl 6-cyano-2,3,4,9-tetrahydro-1H-carbazol-3-ylcarbamate 
• 1353971-24-0 (4-methylamino-cyclohexyl)carbamic acid benzylester 
• 880271-23-8 methyl (4-benzyloxycarbonylaminocyclohexylidene)acetate 
• 1192764-38-7 γ-(carbamic acid benzyl ester)-ε-caprolactone 
• 1378308-05-4 (S)-benzyl (4-(3-methoxypyrrolidin-1-yl)cyclohexyl)carbamate 
• 1378308-06-5 (S)-4-(3-methoxypyrrolidin-1-yl)cyclohexanamine 
• 1226893-02-2 benzyl (2,3-di((8Z,11Z)-heptadeca-8,11-dien-1-yl)-1,4-dioxaspiro[4.5]decan-8-yl)carbamate 
• 1236405-14-3 benzyl ((1r,4r)-4-hydroxy-4-methylcyclohexyl)carbamate 
• 1236405-13-2 benzyl (trans-4-hydroxy-4-methylcyclohexyl)carbamate 
• 7107-59-7 4-(N-Benzyloxycarbonylamino)phenol 
• 1431883-48-5 benzyl (2-oxo-2H-chromen-6-yl)carbamate 

Relevant articles and documents

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