16850-00-3

Basic information

• Product Name: 3-Mercaptopropionic acid benzyl ester
• Synonyms: 3-Mercaptopropionic acid benzyl ester
• CAS NO: 16850-00-3
• Molecular Formula: C₁₀H₁₂O₂S
• Molecular Weight: 196.27
• Mol File: 16850-00-3.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Mercaptopropionic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Mercaptopropionic acid benzyl ester(16850-00-3)
• EPA Substance Registry System: 3-Mercaptopropionic acid benzyl ester(16850-00-3)

Safety Data

• Hazardous Substances Data: 16850-00-3(Hazardous Substances Data)

Usage

Derivation

Derived from benzoic acid and 3-mercaptopropionic acid

Common Uses

Chemical intermediate in organic synthesis
Crosslinking agent in polymer and adhesive production
Production of pharmaceuticals, agricultural chemicals, and fragrances

Odor

Strong odor

Classification

Hazardous material

Importance

Crucial role in various industrial processes and applications

Upstream product

• 952423-86-8 3-(2-benzyloxycarbonyl-ethyldisulfanyl)-propionic acid benzyl ester 
• 107-96-0 3-mercaptopropionic acid 
• 100-51-6 benzyl alcohol 
• 100-39-0 benzyl bromide 

Downstream Products

• 952423-87-9 3-(tetrahydro-furan-2-ylmethylsulfanyl)-propionic acid benzyl ester 
• 122-63-4 benzyl proprionate 

Relevant articles and documents

Poly-6-cationic amphiphilic cyclodextrins designed for gene delivery

A new series of amphiphilic cyclodextrins containing cationic groups at the 6-positions and alkyl or biolabile ester groups at the 2-positions has been synthesised. Selective 2-O-allylation followed by photochemical addition of lipophilic thiols made it possible to control lipophilicity in these mesomolecules and allow solubility and self-assembly in water. The cationic groups are cysteamine-derived, while the alkyl and ester groups are C 1-C16 and benzyl ester groups. This is a new general synthetic route to a potentially wide range of polycationic cyclodextrins capable of acting as gene delivery vectors by condensing DNA and forming liquid crystalline complexes with oligonucleotides.

Mixing End Groups in Thiol-Ene/Yne Reactions as a Simple Approach toward Multienzyme-Responsive Polymeric Amphiphiles

Taking advantage of the high fidelity of thiol-ene and thiol-yne chemistries, we used mixtures of thiols to prepare degradable PEG-dendron amphiphiles functionalized with two different types of enzymatically cleavable end groups. By tuning the feed ratios of the two thiols, we achieved mixtures of hybrids with statistically different ratios of end groups. Studies of the disassembly of statistically mixed hybrids showed that these amphiphiles have higher degrees of response when incubated with each of the activating enzymes, whereas a greater degree of selectivity was observed for a control mixture of two distinct amphiphiles, which required the presence of both types of enzyme to undergo complete disassembly. The potential to introduce different end groups by using a mixture of thiols in an efficient single thiol-ene or thiol-yne step opens the way for simple modification of various ene- or yne-containing polymers and tailoring of their structural and functional properties.

OXIME SULFONATE DERIVATIVES

Oxime sulfonate compounds of the formula (I), wherein R 1 is O(CO)R 4, COOR 5 or CONR 6R 7; n is 1 or 2; R 2 for example is C 1-C 8alkyl, C 3-C 6

Macrocyclic derivative and assemblies formed therefrom

The present invention is directed to a macrocyclic derivative which is formed by modification of a macrocycle. The invention further relates to assemblies formed by the self-assembly of such macrocyclic derivatives in aqueous solvent, and includes bilayer vesicles, micelles, monolayers, nanoparticles, colloidal assemblies and surface-coated assemblies.

ORGANIC COMPOUNDS

The present invention relates to compounds of the formula; and their use in therapy.