169458-93-9

Basic information

• Product Name: Piperazine, 1-[3,5-bis(trifluoromethyl)benzoyl]-2-(1H-indol-3-ylmethyl)-, (2R)-
• CAS NO: 169458-93-9
• Molecular Formula: C22H19F6N3O
• Molecular Weight: 455.403
• Mol File: 169458-93-9.mol

Chemical Properties

• CAS DataBase Reference: Piperazine, 1-[3,5-bis(trifluoromethyl)benzoyl]-2-(1H-indol-3-ylmethyl)-, (2R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperazine, 1-[3,5-bis(trifluoromethyl)benzoyl]-2-(1H-indol-3-ylmethyl)-, (2R)-(169458-93-9)
• EPA Substance Registry System: Piperazine, 1-[3,5-bis(trifluoromethyl)benzoyl]-2-(1H-indol-3-ylmethyl)-, (2R)-(169458-93-9)

Safety Data

• Hazardous Substances Data: 169458-93-9(Hazardous Substances Data)

Upstream product

• 169458-43-9 (2R)-4-benzyl-1-[3,5-bis(trifluoromethyl)benzoyl]-2-(1H-indol-3-yl-methyl)piperazine 
• 7440-44-0 pyrographite 

Downstream Products

• 489437-59-4 (3,5-bis-trifluoromethyl-phenyl)-{2-(1H-indol-3-ylmethyl)-4-[3-(2-methyl-[1,3]dioxolan-2-yl)-propyl]-piperazin-1-yl}-methanone 
• 489437-63-0 4-[4-(3,5-bis-trifluoromethyl-benzoyl)-3-(1H-indol-3-ylmethyl)-piperazin-1-yl]-butan-2-one 
• 489437-47-0 1-[4-(3,5-bis-trifluoromethyl-benzoyl)-3-(1H-indol-3-ylmethyl)-piperazin-1-yl]-propan-2-one 
• 489437-62-9 3-[4-(3,5-bis-trifluoromethyl-benzoyl)-3-(1H-indol-3-ylmethyl)-piperazin-1-yl]-propionaldehyde 
• 489437-61-8 5-[4-(3,5-bis-trifluoromethyl-benzoyl)-3-(1H-indol-3-ylmethyl)-piperazin-1-yl]-pentan-2-one 
• 489437-46-9 2-[4-(3,5-bis-trifluoromethyl-benzoyl)-3-(1H-indol-3-ylmethyl)-piperazin-1-yl]-1-phenyl-ethanone 

Relevant articles and documents

Piperazine derivatives

A piperazine compound of the formula: STR1 wherein: X is carbonyl or sulfonyl; Y is a direct bond or lower alkylene; and R1, R2, R3, R4 are as defined herein. The compounds are advantageously used as Tachykinin antagonists in the treatment of respiratory diseases, ophthalmic diseases and inflammatory diseases, for example.