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3-AMINO-6-BROMO-2-CHLOROPYRIDINE is a chemical compound characterized by its molecular formula C5H4BrClN2 and a molecular weight of 192.46 g/mol. This pale yellow solid is recognized for its role as an intermediate in the synthesis of pharmaceuticals and agrochemicals, making it a significant building block in drug discovery and development. Its unique structure and properties contribute to the creation of innovative products for medical and agricultural applications.

169833-70-9

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169833-70-9 Usage

Uses

Used in Pharmaceutical Industry:
3-AMINO-6-BROMO-2-CHLOROPYRIDINE is used as a key intermediate for the synthesis of potential therapeutic agents, contributing to the development of new drugs with diverse applications in medicine.
Used in Agrochemical Industry:
3-AMINO-6-BROMO-2-CHLOROPYRIDINE is utilized as a building block in the creation of agrochemicals, playing a crucial role in the development of innovative products for agricultural purposes, such as pesticides and herbicides.

Check Digit Verification of cas no

The CAS Registry Mumber 169833-70-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,9,8,3 and 3 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 169833-70:
(8*1)+(7*6)+(6*9)+(5*8)+(4*3)+(3*3)+(2*7)+(1*0)=179
179 % 10 = 9
So 169833-70-9 is a valid CAS Registry Number.
InChI:InChI=1/C5H4BrClN2/c6-4-2-1-3(8)5(7)9-4/h1-2H,8H2

169833-70-9 Well-known Company Product Price

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  • Aldrich

  • (ADE000545)  6-Bromo-2-chloropyridin-3-amine  AldrichCPR

  • 169833-70-9

  • ADE000545-1G

  • 7,411.95CNY

  • Detail

169833-70-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-Bromo-2-chloropyridin-3-amine

1.2 Other means of identification

Product number -
Other names 2-Chloro-6-bromopyridin-3-amine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:169833-70-9 SDS

169833-70-9Relevant articles and documents

HETEROARYL COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE

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Page/Page column 210, (2020/01/24)

The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted benzothiazole compounds of Formula (I) or (II), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.

SMALL MOLECULE INHIBITORS OF DYRK/CLK AND USES THEREOF

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Paragraph 0766-0767, (2020/02/19)

This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a 6,5-heterocyclic structure (e.g., compounds having a imidazopyridine, imidazopyrimidine, imidazopyrazine, imidazopyridazine, imidazotriazine, benzoimidazole, benzotriazole, benzoisoxazole, purine, indazole, triazolotriazine, triazolopyridazine, triazolopyrimidine, triazolopyrazine, triazolotetrazine, triazolopyridine, pyrazolopyrazine, pyrazolopyrimidine, pyrazolopyridazine, pyrazolotriazine, pyrazolopyridine, isoxazolopyrazine, isoxazolopyrimidine, isoxazolopyrdiazine, isoxazolotriazine, or isoxalopyridine structure) which function as inhibitors of DYRK1A, DYRK1B, and Clk-1, and their use as therapeutics for the treatment of Alzheimer's disease, Down syndrome, diabetes, glioblastoma, autoimmune diseases, cancer (e.g., glioblastoma, prostate cancer), inflammatory disorders (e.g., airway inflammation), and other diseases.

PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS

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Page/Page column 87-88, (2016/06/01)

Polycyclic Compounds of formula (I) wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts, stereoisomers, enantiomers, tautomers and N-oxides of those compounds, can be used as insecticides and can be prepared in a manner known per se.

An unusual radical smiles rearrangement

Bacque, Eric,El Qacemi, Myriem,Zard, Samir Z.

, p. 3817 - 3820 (2007/10/03)

(Chemical Equation Presented) Radicals derived from N-(α-xanthyl) acetanilides or N-(α-xanthyl)acetylaminopyridines possessing a substituent next to the nitrogen undergo a hitherto undocumented Smiles rearrangement proceeding through a four-membered ring.

Novel non-nucleoside inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. 4. 2-Substituted dipyridodiazepinones as potent inhibitors of both wild-type and cysteine-181 HIV-1 reverse transcriptase enzymes

Proudfoot,Hargrave,Kapadia,Patel,Grozinger,McNeil,Cullen,Cardozo,Tong,Kelly,Rose,David,Mauldin,Fuchs,Vitous,Hoermann,Klunder,Raghavan,Skiles,et al.

, p. 4830 - 4838 (2007/10/03)

The major cause of viral resistance to the potent human immunodeficiency virus type 1 reverse transcriptase (RT) inhibitor nevirapine is the mutation substituting cysteine for tyrosine-181 in RT (Y181C RT). An evaluation, against Y181C RT, of previously described analogs of nevirapine revealed that the 2-chlorodipyridodiazepinone 16 is an effective inhibitor of this mutant enzyme. The detailed examination of the structure-activity relationship of 2- substituted dipyridodiazepinones presented below shows that combined activity against the wild-type and Y181C enzymes is achieved with aryl substituents at the 2-position of the tricyclic ring system. In addition, the substitution pattern at C-4, N-5, and N-11 of the dipyridodiazepinone ring system optimum for inhibition of both wild-type and Y181C RT is no longer the 4-methyl-11- cyclopropyl substitution preferred against the wild-type enzyme but rather the 5-methyl-11-ethyl (or 11-cyclopropyl) pattern. The more potent 2- substituted dipyridodiazepinones were evaluated against mutant RT enzymes (L100I RT, K103N RT, P236L RT, and E138K RT) that confer resistance to other non-nucleoside RT inhibitors, and compounds 42, 62, and 67, with pyrrolyl, aminophenyl, and aminopyridyl substituents, respectively, at the 2-position, were found to be effective inhibitors of these mutant enzymes also.

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