934266-82-7

Usage

Uses

Used in Pharmaceutical Industry:
2-AMINO-5-BROMOTHIAZOLO[5,4-B]PYRIDINE is used as an intermediate in the synthesis of various pharmaceuticals for its potential biological activities. Its antiparasitic and antitumor properties make it a valuable component in the development of new drugs targeting parasitic infections and cancer treatment.
Used in Agrochemical Industry:
In the agrochemical industry, 2-AMINO-5-BROMOTHIAZOLO[5,4-B]PYRIDINE serves as an intermediate in the synthesis of agrochemicals. Its potential biological activities can be harnessed to develop new compounds for pest control and crop protection, contributing to increased agricultural productivity and food security.
Used in Research and Development:
2-AMINO-5-BROMOTHIAZOLO[5,4-B]PYRIDINE is utilized in research and development for the exploration of its potential applications in various fields. Its unique chemical structure and biological activities make it an attractive candidate for the design and synthesis of novel drugs and chemical compounds with potential therapeutic and industrial applications.

InChI:InChI=1/C6H4BrN3S/c7-4-2-1-3-5(10-4)11-6(8)9-3/h1-2H,(H2,8,9)

Upstream product

• 13534-97-9 6-bromopyridine-3-amine 
• 333-20-0 potassium thioacyanate 
• 1112982-76-9 N-(5-bromothiazolo[5,4-b]pyridin-2-yl)acetamide 
• 169833-70-9 6-bromo-2-chloropyridine-3-ylamine 
• 4487-59-6 2-bromo-5-nitropyridine 
• 5418-51-9 5-nitro-2-hydroxypyridine 

Downstream Products

• 934266-81-6 4-{4-[1-(5-bromo-thiazolo[5,4-b]pyridin-2-ylcarbamoyl)2-cyclopentyl-ethyl]benzenesulfonyl}-piperazine-1-carboxylic acid tert-butyl ester 
• 1440428-02-3 C₆H₂Br₂N₂S 
• 1616589-57-1 5-(2-acetamidothiazolo[5,4-b]pyridin-5-yl)-3-(4-fluorophenylsulfonylamino)-2-methoxybenzamide 
• 1616589-58-2 5-(2-(cyclopropanecarboxamido)thiazolo[5,4-b]pyridin-5-yl)-3-(4-fluorophenylsulfonylamino)-2-methoxybenzamide 
• 1616589-59-3 5-(2-(cyclopropylamino)thiazolo[5,4-b]pyridin-5-yl)-3-(4-fluorophenylsulfonylamino)-2-methoxybenzamide 
• 1355241-50-7 5-bromo-2-chlorothiazolo[5,4-b]pyridine 

Relevant academic research and scientific papers

FUSED AZOLE HETEROCYCLES AS AHR ANTAGONISTS

The present disclosure relates to thiazolo-pyridine, oxazolo-pyridine, pyrrolo-pyridine, pyrrolo-pyrazine and pyrrolo-pyrimidine compounds and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising the same, methods of preparing

HETEROARYL COMPOUNDS AS NECROSIS INHIBITORS, COMPOSITION AND METHOD USING THE SAME

The present disclosure provides heteroaryl compounds of Formula (I), processes for their preparation, pharmaceutical compositions containing them, and their use in the treatment of diseases and disorders, arising from or related to necrosis. Formula (I) i

TRICYCLIC PI3K INHIBITOR COMPOUNDS AND METHODS OF USE

Described herein are tricyclic compounds with phosphoinositide-3 kinase (PI3K) modulation activity or function having the Formula I structure: or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I compounds, as well as methods of using such PI3K modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon PI3K dysregulation.

NOVEL COMPOUNDS AS GPR119 AGONISTS

The present invention relates to novel compounds of formula (I) as GPR119 agonist, composition compositions containing such compounds and method of preparation thereof.

QUINUCLIDINE, 1-AZABICYCLO[2.2.1]HEPTANE, 1-AZABICYCLO [3.2.1]OCTANE, and 1-AZABICYCLO[3.2.2]NONANE COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS

The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds are ligands for the nicotinic α7 receptor and may be useful for the treatment of various disorders of the central nervous system, especially affective and neurodegenerative disorders.

UREA DERIVATIVE HAVING PI3K INHIBITORY ACTIVITY

Provided is a compound or a pharmaceutically acceptable salt thereof which inhibits the activity of PI3K to regulate many biological processes including the growth, differentiation, survival, proliferation, migration, metabolism, and the like of cells and is therefore useful for the prophylaxis/therapy of diseases including inflammatory diseases, arteriosclerosis, vascular/circulatory diseases, cancer/tumors, immune system diseases, cell proliferative diseases, infectious diseases, and the like. The above problem was solved by providing a urea derivative shown in the present specification, or a pharmaceutically acceptable salt thereof.

PI3K/M TOR INHIBITORS

The invention relates to PI3K/mTOR inhibiting compounds consisting of the formula (I): wherein the variables are as defined herein. The invention also relates to pharmaceutical compositions, kits and articles of manufacture comprising such compounds; meth

INHIBITORS OF PHOSPHATIDYLINOSITOL 3-KINASE

The present invention relates to compounds useful as inhibitors of PI3K, particularly of PI3K ggr;. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.

APOPTOSIS SIGNAL-REGULATING KINASE 1 INHIBITORS

The present invention relates to apoptosis signal-regulating kinase 1 (“ASK1”) inhibiting compounds of the formula wherein the variables are as defined herein. The invention also relates to pharmaceutical compositions, kits and articles of manufacture com