170020-91-4

Basic information

• Product Name: 1H-Pyrazole-4-carboxylicacid,1-methyl-,hydrazide(9CI)
• Synonyms: 1H-Pyrazole-4-carboxylicacid,1-methyl-,hydrazide(9CI);1H-Pyrazole-4-carboxylic acid, 1-Methyl-, hydrazide;1-methyl-4-pyrazolecarbohydrazide;1-methylpyrazole-4-carbohydrazide;STK312391;ZINC02537691
• CAS NO: 170020-91-4
• Molecular Formula: C5H8N4O
• Molecular Weight: 140.15
• Product Categories: AMIDE
• Mol File: 170020-91-4.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Pyrazole-4-carboxylicacid,1-methyl-,hydrazide(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazole-4-carboxylicacid,1-methyl-,hydrazide(9CI)(170020-91-4)
• EPA Substance Registry System: 1H-Pyrazole-4-carboxylicacid,1-methyl-,hydrazide(9CI)(170020-91-4)

Safety Data

• Hazardous Substances Data: 170020-91-4(Hazardous Substances Data)

Usage

Derivative of pyrazole

yes

Pharmaceutical applications

potential antifungal agent, building block for drug synthesis

Agricultural applications

controlling diseases in crops

Used as intermediate

in the synthesis of pharmaceutical substances

Fields of interest

medicine, agriculture

Upstream product

• 5952-92-1 1-methyl-1H-pyrazole-4-carboxylic acid 
• 85290-80-8 ethyl 1-methylpyrazole-4-carboxylate 
• 5952-93-2 methyl ester of 1-methylpyrazole-4-carboxylic acid 

Downstream Products

• 1412407-44-3 C₁₉H₂₄N₆OS 
• 1610361-24-4 C₂₀H₂₄N₆OS 

Relevant articles and documents

Synthesis and characterization of novel pyridine associated 1,2,4-triazolo-1,3,4-thiadiazines

A series of novel 3-(1-methyl-1H-pyrazol-4-yl)-6-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadaizine and its derivatives (8a-f) were synthesized by using 1-methyl-1H-pyrazole-4-carboxylic acid (3) as starting material and by involving 1-methyl-1H-pyrazole-

HETEROARYL-SUBSTITUTED TRIAZOLES AS APJ RECEPTOR AGONISTS

Compounds of Formula (I) and Formula (II), pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and may have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures: where the definitions of the variables are provided herein.

Narrow SAR in odorant sensing Orco receptor agonists

The systematic exploration of a series of triazole-based agonists of the cation channel insect odorant receptor is reported. The structure-activity relationships of independent sections of the molecules are examined. Very small changes to the compound structure were found to exert a large impact on compound activity. Optimal substitutions were combined using a 'mix-and-match' strategy to produce best-in-class compounds that are capable of potently agonizing odorant receptor activity and may form the basis for the identification of a new mode of insect behavior modification.