170983-98-9

Basic information

• Product Name: β-4,5-dibenzoyl-2-cyano-D-deoxyribrate
• Synonyms: beta-4,5-dibenzoyl-2-cyano-D-deoxyribrate
• CAS NO: 170983-98-9
• Molecular Formula: C₂₀H₂₁NO₃
• Molecular Weight: 351.35268
• Mol File: 170983-98-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: β-4,5-dibenzoyl-2-cyano-D-deoxyribrate(CAS DataBase Reference)
• NIST Chemistry Reference: β-4,5-dibenzoyl-2-cyano-D-deoxyribrate(170983-98-9)
• EPA Substance Registry System: β-4,5-dibenzoyl-2-cyano-D-deoxyribrate(170983-98-9)

Safety Data

• Hazardous Substances Data: 170983-98-9(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 132487-16-2 methyl 3,5-di-O-benzyl-2-deoxy-D-ribofuranoside 
• 7677-24-9 trimethylsilyl cyanide 
• 6160-49-2 1-O-acetyl-3,5-di-O-benzyl-2-deoxy-D-erythro-pentofuranose 
• 51255-17-5 1-O-methyl-2-deoxy-D-ribofuranoside 
• 100-44-7 benzyl chloride 
• 6160-50-5 3,5-di-O-benzyl-2-deoxy-D-ribofuranose 
• 452-51-7 D-2-deoxyribose 

Downstream Products

• 226232-83-3 5-(3',5'-Di-O-benzyl-2'-desoxy-β-D-ribofuranosyl)-3,6-bis(trifluoromethyl)-1,2,4-triazin 
• 226232-79-7 3,5-Di-O-benzyl-2-desoxy-β-D-ribofuranose-1-imidocarbonsaeuremethylester 

Relevant articles and documents

Base pair recognition ability of 2-(methylamino)pyrimidin-4-yl nucleobase in parallel triplex dna

A phosphoramidite bearing a 2-(methylamino)pyrimidin-4-yl nucleobase was synthesized and the modified oligonucleotide (triplex-forming oligonucleotide, TFO) was successfully obtained using the phosphoramidite on an automated DNA synthesizer. UV-melting ex

Highly stereoselective synthesis of aryl/heteroaryl-: C -nucleosides via the merger of photoredox and nickel catalysis

A photoredox/nickel dual-catalyzed decarboxylative cross-coupling reaction of anomeric ribosyl/deoxyribosyl acids with aryl/heteroaryl bromides has been developed. The reaction proceeds smoothly under visible-light irradiation and features the using of cost-effective and easily handled catalysts and starting materials, which allows the highly stereoselective synthesis of diverse aryl/heteroaryl-C-nucleosides in moderate to high yields.

Stereoselective construction of 1β-azido- And 1β-cyano-2-deoxyribose derivatives

A new method has been developed for the β-selective introduction of azido and cyano groups at the anomeric position of 2-deoxyribose derivatives. This method proceeds via the formation of a collidinium salt intermediate and allows for the stereoselective construction of 1β-azido- and 1β-cyano-2-deoxy-D-ribose derivatives. 2-Deoxy-D-ribose compounds bearing an acetoxy or tert-butoxycarbonyloxy group at their anomeric position performed well as starting materials for the formation of the corresponding 1β-azide and 1β-cyanide derivatives, respectively. 1H NMR studies of the salt intermediates revealed that the nucleophilic substitution reaction of the salt intermediates proceeded in a SN2-fashion.

Synthesis of novel C-nucleosides with potential applications in combinatorial and parallel synthesis

Novel di-substituted pyrimidinyl C-nucleosides have been synthesised using a flexible synthetic methodology. This methodology conveniently allows the synthesis of alpha and beta nucleosides, both of which are of biological interest. Reactive acetylenic ke

Synthesis of novel Pyridine-, Pyrindine- and Isoquinoline-substituted α- and β-C-nucleosides of 2-deoxy-D-ribose

The novel imido esters of 2-deoxy-α- and -β-D-ribose 8 and 9 have been synthesized and successfully transformed to the protected 1,2,4-triazine-C-nucleosides 11 and 12 using an inverse type Diels-Alder reaction with the 1,2,4,5-tetrazine 10. The electron deficient diazadiene system of both C-nucleosides 11 and 12 proved to be highly reactive in a consecutive [4 + 2] cycloaddition with inverse electron demand towards several electron rich dienophiles yielding after successful deprotection the novel pyridine-, pyrindine- and isoquinoline-C-nucleosides 15, 18 and 21 of 2-deoxy-α-D-ribose and 23, 25 and 27 of 2-deoxy-β-D-ribose.