17292-62-5

Basic information

• Product Name: SODIUM HYDROGENCYANAMIDE
• Synonyms: SODIUM HYDROGENCYANAMIDE;MONOSODIUM CYANAMIDE;cyanamide,monosodiumsalt;sodiumacidcyanamide;sodium cyanamidate;Cyanamide monosodium salt, mono-Sodium cyanamide;N-Sodiocyanamide;Sodiocyanoamine
• CAS NO: 17292-62-5
• Molecular Formula: CHN₂*Na
• Molecular Weight: 64.02
• EINECS: 241-322-3
• Product Categories: Materials Science;Metal and Ceramic Science;Salts;Sodium Salts
• Mol File: 17292-62-5.mol

Chemical Properties

• Melting Point: >360 °C(lit.)
• Boiling Point: 258.5°C at 760 mmHg
• Flash Point: 1.2°C
• Appearance: White to tan/Crystalline Powder
• Vapor Pressure: 0.0137mmHg at 25°C
• Storage Temp.: 2-8°C
• BRN: 3624175
• CAS DataBase Reference: SODIUM HYDROGENCYANAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: SODIUM HYDROGENCYANAMIDE(17292-62-5)
• EPA Substance Registry System: SODIUM HYDROGENCYANAMIDE(17292-62-5)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Safety Statements: 26-36
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• RTECS: GS6481050
• F: 3-34
• Hazardous Substances Data: 17292-62-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Production:
Sodium hydrogencyanamide is used as a reducing agent in the synthesis of pharmaceuticals, facilitating various chemical reactions necessary for the production of medicinal compounds.
Used in Organic Compound Synthesis:
SODIUM HYDROGENCYANAMIDE is utilized as a reducing agent in the synthesis of organic compounds, playing a crucial role in the creation of a range of chemical products.
Used in Chemical Reactions:
Sodium hydrogencyanamide is used as a reducing agent for its ability to donate electrons in chemical reactions, which is essential for the transformation of certain substances.
Used in Polymer Stabilization:
In the polymer industry, sodium hydrogencyanamide serves as a stabilizer to enhance the properties of certain polymers, improving their performance and longevity.
Used in Organic Chemical Synthesis:
Sodium hydrogencyanamide is used in the synthesis of various organic chemicals, contributing to the development of a wide array of chemical products.
Safety Note:
Due to the hazardous nature of sodium hydrogencyanamide, including its potential to produce toxic hydrogen cyanide gas when reacting with water, it is imperative that this compound is handled and stored with the utmost care to prevent accidents and ensure safety.

InChI:InChI=1/CHN2.Na/c2-1-3;/h2H;/q-1;+1

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Relevant articles and documents

Sulfoxide-to-sulfilimine conversions: Use of modified Burgess-type reagents

Sulfoxides can directly be converted into N-cyanosulfilimines using a new Burgess-type reagent. By applying this strategy with a related reagent variant, synthetically valuable NH-sulfoximines have been prepared from sulfoxides via N-protected sulfilimines. The practical three-step reaction sequence is generally high yielding and applicable to a wide range of substrates. The sulfoxide-to-sulfilimine conversion can also be performed under solvent-reduced conditions in a ball mill. Copyright

Compounds derived from an amine nucleus and pharmaceutical compositions comprising same

Compounds having the formula (I), are effective as inhibitors of IMPDH enzyme and/or serine protease Factor VIIa, wherein B is a monocyclic or bicyclic carbocyclic or heterocyclic ring, D is a monocyclic or bicyclic carbocyclic or heterocyclic ring except when A is a heterocyclic ring, then D is a heterocyclic ring system, R is hydrogen or C1-4alkyl, and A, R1, R2and R4are as defined in the specification.

Compounds derived from an amine nucleus and pharmaceutical compositions comprising same

Compounds having the formula (I), are effective as inhibitors of IMPDH enzyme and/or serine protease Factor VIIa, wherein B is a monocyclic or bicyclic carbocyclic or heterocyclic ring, D is a monocyclic or bicyclic carbocyclic or heterocyclic ring except when A is a heterocyclic ring, then D is a heterocyclic ring system, R is hydrogen or C1-4alkyl, and A, R1, R2 and R4 are as defined in the specification.

Compounds derived from an amine nucleus that are inhibitors of IMPDH enzyme

The present invention discloses the identification of the novel inhibitors of IMPDH (inosine-5′-monophosphate dehydrogenase). The compounds and pharmaceutical compositions disclosed herein are useful in treating or preventing IMPDH mediated diseases, such as transplant rejection and autoimmune diseases.

Inhibitors of IMPDH enzyme

The present invention discloses the identification of the novel inhibitors of IMPDH (inosine-5′-monophosphate dehydrogenase). The compounds and pharmaceutical compositions disclosed herein are useful in treating or preventing IMPDH-associated disorders, such as transplant rejection and autoimmune diseases.