150-90-3

Basic information

• Product Name: Disodium succinate
• Synonyms: di-Sodiumsuccinatehexahyrate;dlsodiumsuccinate;Jantaran sodny;jantaransodny;Soduxin;Sodium succinate dibasic anhydrous;DISODIUM SUCCINATE 98+%;Succinic Acid Disodium Salt Anhydrous
• CAS NO: 150-90-3
• Molecular Formula: C₄H₄O₄*2Na
• Molecular Weight: 162.05
• EINECS: 205-778-7
• Mol File: 150-90-3.mol
• Article Data: 14

Chemical Properties

• Melting Point: >300°C
• Boiling Point: 236.1 °C at 760 mmHg
• Flash Point: 110.9 °C
• Appearance: White/Crystalline Powder
• Density: 1.46 g/cm3
• Vapor Pressure: 0.0165mmHg at 25°C
• Storage Temp.: Store below +30°C.
• Solubility: 350g/l
• Water Solubility: 300 g/L (25 ºC)
• Merck: 13,8754
• BRN: 3917246
• CAS DataBase Reference: Disodium succinate(CAS DataBase Reference)
• NIST Chemistry Reference: Disodium succinate(150-90-3)
• EPA Substance Registry System: Disodium succinate(150-90-3)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36-24/25
• WGK Germany: 1
• RTECS: WM7751000
• F: 3
• TSCA: Yes
• Hazardous Substances Data: 150-90-3(Hazardous Substances Data)

Usage

Chemical Properties

Different sources of media describe the Chemical Properties of 150-90-3 differently. You can refer to the following data:
1. Reported found in condiments
2. white crystalline powder

Occurrence

Disodium phosphate is anhydrous or contains two molecules of water of hydration

Uses

Succinic acid disodium salt is used to prepare buffer solution for the quantitative analysis of auxins.It can be also used:???????? To study the effect of liquid phase on the basic properties of α-tricalcuim phosphate (α-TCP) based cement, BIOPEX.????????In the synthesis of cadmium sulfide (CdS) nanoparticles using thiourea as a source for sulfide.

Definition

ChEBI: A sodium salt that is the disodium salt of succinic acid. The hexahydrate form is used as an ingredient of topical preparations for the treatment of cataract.

General Description

Disodium succinate is used in the food industry as an acidity regulator and flavor enhancer.

Flammability and Explosibility

Notclassified

Purification Methods

Crystallise it twice from water (1.2mL/g) and dry it at 125o. It has been freed from other metal ions by passage of a 0.1M solution through a column of Dowex resin A-1 (Na form). It is hygroscopic. [Beilstein 2 H 606, 2 IV 1908.]

InChI:InChI=1/C4H6O4.2Na/c5-3(6)1-2-4(7)8;;/h1-2H2,(H,5,6)(H,7,8);;/q;2*+1/p-2

Synthetic route

sodium acetate (127-09-3) → sodium succinate (150-90-3) + sodium acetate radical

Conditions	Yield
In water-d2 Irradiation;

sodium maleate (3105-55-3, 5873-57-4, 7704-73-6, 17013-01-3, 18016-19-8, 30915-61-8, 44670-32-8, 54060-75-2, 72383-56-3, 371-47-1) → sodium succinate (150-90-3) + fumaric acid disodium salt (17013-01-3)

Conditions	Yield
With hydrogen; nickel at 30℃; under 735.06 Torr; for 0.5h; Product distribution;

succinic acid monomethyl ester sodium salt (50888-28-3) → sodium succinate (150-90-3)

Conditions	Yield
With sodium hydroxide In methanol; water at 20℃; Rate constant; Thermodynamic data; ΔH(excit.), ΔS(excit.); various solvents;
With sodium hydroxide at 25℃; Kinetics; Further Variations:; Temperatures; Solvents; Hydrolysis;

succinic acid monopropyl ester sodium salt (69361-29-1) → sodium succinate (150-90-3)

Conditions	Yield
With sodium hydroxide In water; acetone at 30℃; Rate constant; various solvents;

sodium glycolate (25289-18-3, 105938-46-3, 2836-32-0) + alkali + zinc → sodium succinate (150-90-3)

magnesium succinate (556-32-1, 33460-47-8) → sodium succinate (150-90-3)

Conditions	Yield
With sodium hydroxide In water for 1h; pH=12.4;
With sodium hydroxide In water for 1h; pH=12.4; Product distribution / selectivity;

calcium succinate (140-99-8, 25454-25-5, 27695-01-8, 27695-02-9, 27695-03-0) → sodium succinate (150-90-3)

Conditions	Yield
With sodium carbonate In water for 1h; pH=10.5;
With sodium carbonate In water for 1h; pH=10.5; Product distribution / selectivity;

α-ketoglutaric acid disodium salt (305-72-6) → sodium succinate (150-90-3)

Conditions	Yield
With hydrogenchloride; iron(II) ammonium sulfate; pseudomonas sp.AK1 γ-butyrobetaine hydroxylase; potassium chloride; γ-butyrobetaine hydrochloride In water-d2 pH=7.5; Kinetics; Reagent/catalyst; Enzymatic reaction;

succinic acid (110-15-6) + sodium carbonate (497-19-8) → sodium succinate (150-90-3)

Conditions	Yield
In water

succinic acid anhydride (108-30-5) → sodium succinate (150-90-3)

Conditions	Yield
With water; sodium hydroxide for 0.00277778h; pH=12.8;	>= 95 %Spectr.

butanedioic acid, monoethyl ester (1070-34-4) → sodium succinate (150-90-3)

Conditions	Yield
With water; sodium hydroxide for 0.00555556h; pH=13;	>= 95 %Spectr.

sodium maleate (3105-55-3, 5873-57-4, 7704-73-6, 17013-01-3, 18016-19-8, 30915-61-8, 44670-32-8, 54060-75-2, 72383-56-3, 371-47-1) → sodium succinate (150-90-3)

Conditions	Yield
With hydrogen; sodium hydroxide In methanol; water at 29.84℃; Kinetics; Catalytic behavior; Solvent;

Tetrahydrofurfuryl alcohol (97-99-4) + sodium succinate (150-90-3) → malic acid (617-48-1) + (tetrahydrofuran-2-ylmethoxy)butanedioic acid

Conditions	Yield
With lanthanum(III) chloride at 116℃; for 19h; Product distribution; also with other alcohols; variation of reaction time, temperature and proportion of reagents;	A 3% B 95%

[2,2]bipyridinyl (366-18-7) + copper(II) perchlorate hexahydrate + sodium succinate (150-90-3) → ([Cu2(succinato)2(2,2'-bipyridine)4(H2O)2](ClO4)4(H2O))(n)

Conditions	Yield
In methanol; water a MeOH soln. of 2,2'-bipyridine added dropwise to a MeOH soln. of Cu salt with stirring for 15 min, an aq. soln. of disodium succinate added slowly, refluxed for 2 h; cooled, filtered, kept in a CaCl2-desiccator for days; elem. anal.;	90%

tributyltin chloride (1461-22-9) + sodium succinate (150-90-3) → (n-Bu)3SnO2CCH2CH2CO2Sn(Bu-n)3

Conditions	Yield
In ethanol under N2 atm. disodium dicarboxylate was added to EtOH soln. (n-Bu)3SnCland stirred for 15 h at 40°C; soln. was filtered and evapd., residue was recrystd. from EtOH; elem. anal.;	85.5%

1,10-Phenanthroline (66-71-7) + copper(II) nitrate trihydrate + sodium succinate (150-90-3) → [Cu2(μ-OH2)2(succinato)(1,10-phenanthroline)2(NO3)2](n)

Conditions	Yield
In methanol; water a MeOH soln. of 1,10-phenanthroline added dropwise to a MeOH soln. of Cusalt with stirring for 15 min, an aq. soln. of disodium succinate added slowly, refluxed for 2 h; cooled, filtered, kept in a CaCl2-desiccator for days; elem. anal.;	85%

praseodymium(III) chloride hexahydrate + sodium succinate (150-90-3) → [Pr2(succinato)3(H2O)2]*0.5H2O

Conditions	Yield
In water High Pressure; a soln. of Na salt added to a soln. of Pr salt with stirring, heated at 175°C; crystd. overnight by cooling to room temp.; elem. anal.;	82%

methanol (67-56-1) + N,N'-bis[2-carboxybenzomethyl]-N,N'-bis[2-pyridylmethyl]-1,3-diaminopropan-2-ol + water (7732-18-5) + sodium succinate (150-90-3) + sodium hydroxide (1310-73-2) + zinc(II) chloride (7646-85-7) → 4C31H29N4O5(3-)*2C4H4O4(2-)*10H2O*Na(1+)*2H3O(1+)*2Li(1+)*8Zn(2+)*23H2O*6CH4O*2Cl(1-)*3Br(1-)

Conditions	Yield
Stage #1: methanol; N,N'-bis[2-carboxybenzomethyl]-N,N'-bis[2-pyridylmethyl]-1,3-diaminopropan-2-ol; sodium hydroxide; zinc(II) chloride for 1h; Reflux; Stage #2: water; sodium succinate for 1h; Reflux;	82%

sodium succinate (150-90-3) + 1-chloromethylbenzindol-2(1H)-one (CMBI) (114044-23-4) → BIM hydrogen succinate (114044-30-3) + Succinic acid bis-(2-oxo-2H-benzo[cd]indol-1-ylmethyl) ester (114044-39-2)

Conditions	Yield
In N,N-dimethyl-formamide at 100℃; for 0.333333h;	A n/a B 80%

[fac-Mn(CO)3(1,2-bis(diphenylphosphino)ethane)(OH2)]BF4 (247939-31-7) + sodium succinate (150-90-3) → [(carbonyl)3 (bis(diphenylphosphino)ethan) manganese(I) (succinate) (manganese(I) (bis(diphenylphosphino)ethan) (carbonyl)3]

Conditions	Yield
In chloroform; water (Ar); sodium succinate dissolved in water; to CHCl3 soln. of (CO)3(dppe)Mn(OH2)BF4 equimolar quantity of new ligand added dropwise; stirring continued for 10-20 min; CHCl3 soln. separated; washed with water; dried and evaporated; resulting solids washed with hexane; dried in vacuo;	80%

gadolinium(III) nitrate hexahydrate + sodium succinate (150-90-3) → [Gd2(succinato)3(H2O)2]*0.5H2O

Conditions	Yield
In water High Pressure; a soln. of Na salt added to a soln. of Gd salt with stirring for 10 min,heated for 24 h at 175°C; crystd. overnight by cooling to room temp.; elem. anal.;	80%

samarium(III) chloride hexahydrate + sodium succinate (150-90-3) → [Sm2(succinato)3(H2O)2]*0.5H2O

Conditions	Yield
In water High Pressure; a soln. of Na salt added to a soln. of Sm salt with stirring, heated at 175°C; crystd. overnight by cooling to room temp.; elem. anal.;	80%

[2,2]bipyridinyl (366-18-7) + copper(II) nitrate trihydrate + sodium succinate (150-90-3) → [Cu2(succinate)(2,2'-bipyridyl)4](nitrate)2*10.5water

Conditions	Yield
In ethanol; water addn. of ethanolic soln. of bipyridine to aq. soln. of succinate salt toaq. soln. of copper compd., heating to 90°C; filtration, keeping at room temp. for 5 d with slow evapn., isolation ofcrystals, washing with cold water and ether, drying in open air, elem. anal.;	80%

sodium succinate (150-90-3) + benzoyl chloride (98-88-4) → benzoic acid anhydride (93-97-0) + benzoic acid (65-85-0)

Conditions	Yield
With Pyridine 1-oxide hydrochloride In dichloromethane; water at 18℃; Rate constant;	A 19% B 79%

tetra(thiourea)zinc chloride + sodium succinate (150-90-3) → di(thiourea)zinc (μ-succinate)

Conditions	Yield
In water 1 equiv. of ligand in H2O added to Zn complex in H2O; crystd. for several days, filtered, elem. anal., XRD, TGA;	78%

[2,2]bipyridinyl (366-18-7) + copper(II) nitrate trihydrate + sodium succinate (150-90-3) → [Cu2(μ-OH2)2(succinato)(2,2'-bipyridine)2(NO3)2](n)

Conditions	Yield
In methanol; water a MeOH soln. of 2,2'-bipyridine added dropwise to a MeOH soln. of Cu salt with stirring for 15 min, an aq. soln. of disodium succinate added slowly, refluxed for 2 h; cooled, filtered, kept in a CaCl2-desiccator for 7 d; elem. anal.;	78%

neodymium(III) nitrate hexahydrate + sodium succinate (150-90-3) → [Nd2(succinato)3(H2O)2]*0.5H2O

Conditions	Yield
In water High Pressure; a soln. of Na salt added to a soln. of Nd salt with stirring, heated at 175°C; crystd. overnight by cooling to room temp.; elem. anal.;	78%

2,2'-biimidazole (492-98-8) + copper(II) nitrate trihydrate + sodium succinate (150-90-3) → [[Cu(2,2'-biimidazole)(H2O)(succinate)](H2O)]n

Conditions	Yield
In methanol; water 1 equiv. of Cu-salt in H2O was dropwise added to MeOH soln. of biimidazole-compd., 1 equiv. of aq. soln. of the Na-salt was added, reflux for 12h; cooling to room temp., soln. was filtered, filtrate was kept in a desiccator over CaCl2, crystn. for a few weeks, elem. anal.;	78%

cadmium(II) nitrate tetrhydrate + water (7732-18-5) + sodium succinate (150-90-3) + 2,5-bis-(4-pyridyl)-3,4-diaza-2,4-hexadiene → {[Cd(2,5-bis-(4-pyridyl)-3,4-diaza-2,4-hexadiene)(succinate)]·(H2O)3}n

Conditions	Yield
In methanol	78%

methanol (67-56-1) + copper(II) choride dihydrate + N,N'-bis[2-carboxybenzomethyl]-N,N'-bis[2-pyridylmethyl]-1,3-diaminopropan-2-ol + sodium succinate (150-90-3) + sodium hydroxide (1310-73-2) → 2Li(1+)*2Na(1+)*4Cu(2+)*2C31H29N4O5(3-)*2C4H4O4(2-)*2CH4O*10H2O*2Cl(1-)

Conditions	Yield
Stage #1: methanol; copper(II) choride dihydrate; N,N'-bis[2-carboxybenzomethyl]-N,N'-bis[2-pyridylmethyl]-1,3-diaminopropan-2-ol; sodium hydroxide at 20℃; for 1h; Stage #2: sodium succinate for 1h;	78%

zinc(II) nitrate hexahydrate + water (7732-18-5) + sodium succinate (150-90-3) + trans-1,2-bis(4-pyridyl)ethylene (1135-32-6) → {[Zn(succinate)(1,2-bis(4-pyridyl)ethylene)]2·(H2O)3}n

Conditions	Yield
In methanol	76%

1,10-Phenanthroline (66-71-7) + copper(II) tetrafluoroborate hydrate + sodium succinate (150-90-3) → [Cu8(succinato)4(1,10-phenanthroline)12](BF4)8*8H2O

Conditions	Yield
In methanol; water a MeOH soln. of 1,10-phenanthroline added dropwise to an aq. soln. of Cusalt with stirring for 15 min, an aq. soln. of disodium succinate added slowly, refluxed for 20 min; cooled, filtered, kept in a CaCl2-desiccator for 4 d; elem. anal.;	75%

europium(III) chloride hexahydrate + sodium succinate (150-90-3) → [Eu2(succinato)3(H2O)2]*0.5H2O

Conditions	Yield
In water High Pressure; a soln. of Na salt added to a soln. of Eu salt with stirring, heated at 175°C; crystd. overnight by cooling to room temp.; elem. anal.;	75%

Glauber's salt + samarium(III) chloride hexahydrate + sodium succinate (150-90-3) → [Sm2(succinate)2(SO4)(H2O)2]

Conditions	Yield
In water at 175℃; for 24.5h;	75%

cadmium(II) nitrate tetrhydrate + water (7732-18-5) + sodium succinate (150-90-3) + N,N’-bis(1-pyridine-3-yl-ethylidene)hydrazine → {[Cd(2,5-bis-(3-pyridyl)-3,4-diaza-2,4-hexadiene)(succinate)]·(H2O)4}n

Conditions	Yield
In methanol	74%

1,2-bis(4'-pyridyl)ethane (4916-57-8) + cadmium(II) nitrate tetrhydrate + water (7732-18-5) + sodium succinate (150-90-3) → {[Cd3(1, 2-bis(4-pyridyl) ethane)3(succinate)2(H2O)2]·(NO3)2(H2O)4}n

Conditions	Yield
In methanol	74%

zinc(II) nitrate hexahydrate + water (7732-18-5) + sodium succinate (150-90-3) + 1,4-bis(3-pyridyl)-2,3-diaza-1,3-butadiene (13362-77-1) → {[Zn(succinate)(1,4-bis(3-pyridyl)-2,3-diaza-1,3-butadiene)]·(H2O)2}n

Conditions	Yield
In methanol	71%

dysprosium(III) nitrate pentahydrate + sodium succinate (150-90-3) → [Dy2(succinato)3(H2O)2]*0.5H2O

Conditions	Yield
In water High Pressure; a soln. of Na salt added to a soln. of Dy salt with stirring, heated at 175°C; crystd. overnight by cooling to room temp.; elem. anal.;	70%

cobalt(II) chloride hexahydrate + sodium succinate (150-90-3) + p,p'-diaminobiphenyl (92-87-5) → [Co(benzidine)2(μ-succinate)(OH2)2]*(H2O)

Conditions	Yield
In methanol; water at 20℃;	70%

sodium succinate (150-90-3) + sodium D-gluconate (527-07-1) → trisodium 2-[(D-gluconate)-2-O-yl]butanedioate

Conditions	Yield
With lanthanum(III) chloride In water for 10.25h; Heating;	69.6%

zinc(II) nitrate hexahydrate + water (7732-18-5) + sodium succinate (150-90-3) + 4-pyridinealdazine (6957-22-8) → {[Zn4(1,4-bis(4-pyridyl)-2,3-diaza-1,3-butadiene)2(succinate)3(OH)2]·5H2O}n

Conditions	Yield
In methanol	69%

Upstream product

• 127-09-3 sodium acetate 
• 3105-55-3 sodium maleate 
• 50888-28-3 succinic acid monomethyl ester sodium salt 
• 69361-29-1 succinic acid monopropyl ester sodium salt 
• 25289-18-3 sodium glycolate 
• 556-32-1 magnesium succinate 
• 140-99-8 calcium succinate 
• 305-72-6 α-ketoglutaric acid disodium salt 
• 110-15-6 succinic acid 
• 497-19-8 sodium carbonate 
• 108-30-5 succinic acid anhydride 
• 1070-34-4 butanedioic acid, monoethyl ester 

Downstream Products

• 480-97-7 4-hydroxybenzofuran 
• 2243-53-0 styrylacetic acid 
• 13389-88-3 5-oxo-2-phenyl-tetrahydro-furan-3-carboxylic acid 
• 13389-99-6 methyl trans-5-oxo-2-phenyltetrahydrofuran-3-carboxylate 
• 13389-88-3 (+/-)-5-oxo-2r-phenyl-tetrahydro-furan-3t-carboxylic acid 
• 766-39-2 2,3-Dimethylmaleic anhydride 
• 18434-42-9 bis-(3-phenyl-allylidene)-succinic acid anhydride 
• 75587-64-3 1,8-diphenylcyclooctatetraene 
• 534-60-1 5-carboxymethyl-2-methyl-furan-3-carboxylic acid 
• 5438-29-9 2-(3-nitro-phenyl)-5-oxo-tetrahydro-furan-3-carboxylic acid 
• 86841-95-4 2-(4-nitro-phenyl)-5-oxo-tetrahydro-furan-3-carboxylic acid 
• 188290-36-0 thiophene 
• 288-05-1 selenophene 
• 108-30-5 succinic acid anhydride 

Related news

The study of phase behavior of aqueous 1-propanol/2-propanol/2-butanol/2-methyl-2-propanol systems in the presence of disodium tartrate or Disodium succinate (cas 150-90-3) at T=298.15K09/28/2019

Liquid–liquid equilibria (LLE) of the 1-propanol/2-propanol/2-butanol/2-methyl-2-propanol+disodium tartrate or disodium succinate+water systems have been measured at T=298.15K. The Merchuk et al. equation was used to correlate the obtained binodal data. The effect of some factors such as length...detailed

Relevant articles and documents

Hydrogenation and Isomerization of Disodium Maleate in the Solid Phase over Fine Nickel Powder

Disodium maleate was converted to a mixture of disodium maleate, fumarate, and succinate in the solid phase when particles of the starting material were kept in contact with fine nickel powder pretreated with hydrogen gas at 200 deg C.

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